Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins
Hynes, Alexander P., Rousseau, Geneviève M., Agudelo, Daniel, Goulet, Adeline, Amigues, Beatrice, Loehr, Jeremy, Romero, Dennis A., Fremaux, Christophe, Horvath, Philippe, Doyon, Yannick, Cambillau, Christian, Moineau, Sylvain
Published in Nature communications (25.07.2018)
Published in Nature communications (25.07.2018)
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Journal Article
Common Oral Medications Lead to Prophage Induction in Bacterial Isolates from the Human Gut
Sutcliffe, Steven G, Shamash, Michael, Hynes, Alexander P, Maurice, Corinne F
Published in Viruses (11.03.2021)
Published in Viruses (11.03.2021)
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Journal Article
Temperate phage-antibiotic synergy across antibiotic classes reveals new mechanism for preventing lysogeny
Al-Anany, Amany M, Fatima, Rabia, Nair, Gayatri, Mayol, Jordan T, Hynes, Alexander P
Published in mBio (12.06.2024)
Published in mBio (12.06.2024)
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Journal Article
DNA packaging bias and differential expression of gene transfer agent genes within a population during production and release of the Rhodobacter capsulatus gene transfer agent, RcGTA
Hynes, Alexander P., Mercer, Ryan G., Watton, David E., Buckley, Colleen B., Lang, Andrew S.
Published in Molecular microbiology (01.07.2012)
Published in Molecular microbiology (01.07.2012)
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Journal Article
Efficacy of Salmonella Bacteriophage S1 Delivered and Released by Alginate Beads in a Chicken Model of Infection
Gomez-Garcia, Janeth, Chavez-Carbajal, Alejandra, Segundo-Arizmendi, Nallelyt, Baron-Pichardo, Miriam G, Mendoza-Elvira, Susana E, Hernandez-Baltazar, Efren, Hynes, Alexander P, Torres-Angeles, Oscar
Published in Viruses (25.09.2021)
Published in Viruses (25.09.2021)
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Journal Article
Metabolomic Investigation of the Bacterial Response to a Metal Challenge
Tremaroli, Valentina, Workentine, Matthew L, Weljie, Aalim M, Vogel, Hans J, Ceri, Howard, Viti, Carlo, Tatti, Enrico, Zhang, Ping, Hynes, Alexander P, Turner, Raymond J, Zannoni, Davide
Published in Applied and Environmental Microbiology (01.02.2009)
Published in Applied and Environmental Microbiology (01.02.2009)
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Journal Article
Adaptation in bacterial CRISPR-Cas immunity can be driven by defective phages
Hynes, Alexander P., Villion, Manuela, Moineau, Sylvain
Published in Nature communications (24.07.2014)
Published in Nature communications (24.07.2014)
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Journal Article
Temperate phage-antibiotic synergy eradicates bacteria through depletion of lysogens
Al-Anany, Amany M., Fatima, Rabia, Hynes, Alexander P.
Published in Cell reports (Cambridge) (25.05.2021)
Published in Cell reports (Cambridge) (25.05.2021)
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Journal Article
An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9
Hynes, Alexander P., Rousseau, Geneviève M., Lemay, Marie-Laurence, Horvath, Philippe, Romero, Dennis A., Fremaux, Christophe, Moineau, Sylvain
Published in Nature microbiology (01.10.2017)
Published in Nature microbiology (01.10.2017)
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Journal Article
Detecting natural adaptation of the Streptococcus thermophilus CRISPR-Cas systems in research and classroom settings
Hynes, Alexander P, Lemay, Marie-Laurence, Trudel, Luc, Deveau, Hélène, Frenette, Michel, Tremblay, Denise M, Moineau, Sylvain
Published in Nature protocols (01.03.2017)
Published in Nature protocols (01.03.2017)
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Journal Article
Applications of CRISPR-Cas in its natural habitat
Hynes, Alexander P, Lemay, Marie-Laurence, Moineau, Sylvain
Published in Current opinion in chemical biology (01.10.2016)
Published in Current opinion in chemical biology (01.10.2016)
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Journal Article
Functional and Evolutionary Characterization of a Gene Transfer Agent's Multilocus "Genome"
Hynes, Alexander P, Shakya, Migun, Mercer, Ryan G, Grüll, Marc P, Bown, Luke, Davidson, Fraser, Steffen, Ekaterina, Matchem, Heidi, Peach, Mandy E, Berger, Tim, Grebe, Katherine, Zhaxybayeva, Olga, Lang, Andrew S
Published in Molecular biology and evolution (01.10.2016)
Published in Molecular biology and evolution (01.10.2016)
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Journal Article