Beyond the neuron–cellular interactions early in Alzheimer disease pathogenesis
Henstridge, Christopher M., Hyman, Bradley T., Spires-Jones, Tara L.
Published in Nature reviews. Neuroscience (01.02.2019)
Published in Nature reviews. Neuroscience (01.02.2019)
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Journal Article
Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
de Calignon, Alix, Polydoro, Manuela, Suárez-Calvet, Marc, William, Christopher, Adamowicz, David H., Kopeikina, Kathy J., Pitstick, Rose, Sahara, Naruhiko, Ashe, Karen H., Carlson, George A., Spires-Jones, Tara L., Hyman, Bradley T.
Published in Neuron (Cambridge, Mass.) (23.02.2012)
Published in Neuron (Cambridge, Mass.) (23.02.2012)
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Journal Article
Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer’s disease
Bennett, Rachel E., Robbins, Ashley B., Hu, Miwei, Cao, Xinrui, Betensky, Rebecca A., Clark, Tim, Das, Sudeshna, Hyman, Bradley T.
Published in Proceedings of the National Academy of Sciences - PNAS (06.02.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (06.02.2018)
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Journal Article
APOE4 derived from astrocytes leads to blood-brain barrier impairment
Jackson, Rosemary J, Meltzer, Jonah C, Nguyen, Huong, Commins, Caitlin, Bennett, Rachel E, Hudry, Eloise, Hyman, Bradley T
Published in Brain (London, England : 1878) (21.10.2022)
Published in Brain (London, England : 1878) (21.10.2022)
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Journal Article
Characterization of the 18 kDa translocator protein (TSPO) expression in post‐mortem normal and Alzheimer's disease brains
Gui, Yaxing, Marks, Jordan D., Das, Sudeshna, Hyman, Bradley T., Serrano‐Pozo, Alberto
Published in Brain pathology (Zurich, Switzerland) (01.01.2020)
Published in Brain pathology (Zurich, Switzerland) (01.01.2020)
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Journal Article
Machine learning identifies candidates for drug repurposing in Alzheimer’s disease
Rodriguez, Steve, Hug, Clemens, Todorov, Petar, Moret, Nienke, Boswell, Sarah A., Evans, Kyle, Zhou, George, Johnson, Nathan T., Hyman, Bradley T., Sorger, Peter K., Albers, Mark W., Sokolov, Artem
Published in Nature communications (15.02.2021)
Published in Nature communications (15.02.2021)
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Journal Article
Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration
Noori, Ayush, Mezlini, Aziz M., Hyman, Bradley T., Serrano-Pozo, Alberto, Das, Sudeshna
Published in Neurobiology of disease (01.02.2021)
Published in Neurobiology of disease (01.02.2021)
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Journal Article
Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration
Das, Sudeshna, Li, Zhaozhi, Noori, Ayush, Hyman, Bradley T, Serrano-Pozo, Alberto
Published in Journal of neuroinflammation (31.07.2020)
Published in Journal of neuroinflammation (31.07.2020)
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Journal Article
Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase
Hernández-Vega, Amayra, Braun, Marcus, Scharrel, Lara, Jahnel, Marcus, Wegmann, Susanne, Hyman, Bradley T., Alberti, Simon, Diez, Stefan, Hyman, Anthony A.
Published in Cell reports (Cambridge) (05.09.2017)
Published in Cell reports (Cambridge) (05.09.2017)
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Journal Article
Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes
Chung, Won-Suk, Verghese, Philip B., Chakraborty, Chandrani, Joung, Julia, Hyman, Bradley T., Ulrich, Jason D., Holtzman, David M., Barres, Ben A.
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2016)
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Journal Article
Poor Performance on a Preoperative Cognitive Screening Test Predicts Postoperative Complications in Older Orthopedic Surgical Patients
Culley, Deborah J, Flaherty, Devon, Fahey, Margaret C, Rudolph, James L, Javedan, Houman, Huang, Chuan-Chin, Wright, John, Bader, Angela M, Hyman, Bradley T, Blacker, Deborah, Crosby, Gregory
Published in Anesthesiology (Philadelphia) (01.11.2017)
Published in Anesthesiology (Philadelphia) (01.11.2017)
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Journal Article
Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism
Cooper, Joanna M., Lathuiliere, Aurelien, Migliorini, Mary, Arai, Allison L., Wani, Mashhood M., Dujardin, Simon, Muratoglu, Selen C., Hyman, Bradley T., Strickland, Dudley K.
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue
Marquié, Marta, Normandin, Marc D., Vanderburg, Charles R., Costantino, Isabel M., Bien, Elizabeth A., Rycyna, Lisa G., Klunk, William E., Mathis, Chester A., Ikonomovic, Milos D., Debnath, Manik L., Vasdev, Neil, Dickerson, Bradford C., Gomperts, Stephen N., Growdon, John H., Johnson, Keith A., Frosch, Matthew P., Hyman, Bradley T., Gómez-Isla, Teresa
Published in Annals of neurology (01.11.2015)
Published in Annals of neurology (01.11.2015)
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Journal Article
Oxidative stress and lipid peroxidation are upstream of amyloid pathology
Arimon, Muriel, Takeda, Shuko, Post, Kathryn L, Svirsky, Sarah, Hyman, Bradley T, Berezovska, Oksana
Published in Neurobiology of disease (01.12.2015)
Published in Neurobiology of disease (01.12.2015)
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Journal Article
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice
Caballero, Benjamin, Bourdenx, Mathieu, Luengo, Enrique, Diaz, Antonio, Sohn, Peter Dongmin, Chen, Xu, Wang, Chao, Juste, Yves R., Wegmann, Susanne, Patel, Bindi, Young, Zapporah T., Kuo, Szu Yu, Rodriguez-Navarro, Jose Antonio, Shao, Hao, Lopez, Manuela G., Karch, Celeste M., Goate, Alison M., Gestwicki, Jason E., Hyman, Bradley T., Gan, Li, Cuervo, Ana Maria
Published in Nature communications (14.04.2021)
Published in Nature communications (14.04.2021)
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