HCV eradication does not impact gut dysbiosis or systemic inflammation in cirrhotic patients
Bajaj, J. S., Sterling, R. K., Betrapally, N. S., Nixon, D. E., Fuchs, M., Daita, K., Heuman, D. M., Sikaroodi, M., Hylemon, P. B., White, M. B., Ganapathy, D., Gillevet, P. M.
Published in Alimentary pharmacology & therapeutics (01.09.2016)
Published in Alimentary pharmacology & therapeutics (01.09.2016)
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Journal Article
HCV Eradication does not Impact Gut Dysbiosis or Systemic Inflammation in Cirrhotic Patients
Bajaj, J.S.S, Sterling, R, Hylemon, P, Nixon, D, Fuchs, M, Heuman, D, Sikaroodi, M, Gillevet, P
Published in Journal of hepatology (2016)
Published in Journal of hepatology (2016)
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Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis
Qiao, L, Studer, E, Leach, K, McKinstry, R, Gupta, S, Decker, R, Kukreja, R, Valerie, K, Nagarkatti, P, El Deiry, W, Molkentin, J, Schmidt-Ullrich, R, Fisher, P B, Grant, S, Hylemon, P B, Dent, P
Published in Molecular biology of the cell (01.09.2001)
Published in Molecular biology of the cell (01.09.2001)
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The Beneficial Impact of Rifaximin on Systemic and Intestinal Inflammation and Ammonia Occurs even without Microbiota: More than an Antibiotic
Kang, D.J, Balfour Sartor, R, Betrapally, N, Nittono, H, Herzog, J, Hylemon, P, SIkaroodi, M, Gillevet, P, Carroll, I, Kakiyama, G, Zhou, H, Yang, J, Jiao, C, Fan, S, Fiehn, O, Takei, H, Pandak, W, Bajaj, J.S.S
Published in Journal of hepatology (2016)
Published in Journal of hepatology (2016)
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P499 ALTERED GUT MICROBIOME IS ASSOCIATED WITH NEURO-INFLAMMATION ON BRAIN MRI IN CIRRHOSIS: IMPLICATIONS FOR THE GUT–LIVER–BRAIN AXIS
Bajaj, J.S, Ahluwalia, V.S, Sikaroodi, M, Wade, J, White, M, Heuman, D, Gilles, H, Unser, A, Hylemon, P, Gillevet, P.M
Published in Journal of hepatology (01.04.2014)
Published in Journal of hepatology (01.04.2014)
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Journal Article
Bile acid metabolism by fresh human colonic contents: a comparison of caecal versus faecal samples
Thomas, L A, Veysey, M J, French, G, Hylemon, P B, Murphy, G M, Dowling, R H
Published in Gut (01.12.2001)
Published in Gut (01.12.2001)
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P335 DYSFUNCTIONAL GUT MICROBIOTA IN ILEO-COLONIC MUCOSA AND STOOL IN ALCOHOLIC CIRRHOSIS IS ASSOCIATED WITH ENDOTOXEMIA: IMPLICATIONS FOR BACTERIAL TRANSLOCATION
Bajaj, J.S, Heuman, D, Hylemon, P, Sikaroodi, M, Ridlon, J, Pandak, W.M, Schubert, M, Fuchs, M, White, M, Daita, K, Gillevet, P
Published in Journal of hepatology (01.04.2014)
Published in Journal of hepatology (01.04.2014)
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Journal Article
Detection of the steroidogenic acute regulatory protein, StAR, in human liver cells
Hall, E.A., Ren, S., Hylemon, P.B., Rodriguez-Agudo, D., Redford, K., Marques, D., Kang, D., Gil, G., Pandak, W.M.
Published in Biochimica et biophysica acta (15.04.2005)
Published in Biochimica et biophysica acta (15.04.2005)
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Down-regulation of Cholesterol 7α-Hydroxylase (CYP7A1) Gene Expression by Bile Acids in Primary Rat Hepatocytes Is Mediated by the c-Jun N-terminal Kinase Pathway
Gupta, Seema, Stravitz, R. Todd, Dent, Paul, Hylemon, Phillip B.
Published in The Journal of biological chemistry (11.05.2001)
Published in The Journal of biological chemistry (11.05.2001)
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192 RIFAXIMIN IMPROVES COGNITION AND ENDOTOXEMIA IN MINIMAL HEPATIC ENCEPHALOPATHY BY SHIFTING GUT MICROBIAL FUNCTIONALITY WITHOUT ALTERING THEIR ABUNDANCE
Bajaj, J.S, Heuman, D, Sanyal, A, Hylemon, P, Sterling, R.K, Stravitz, R.T, Fuchs, M, Ridlon, J.M, Daita, K, Monteith, P, White, M, Noble, N.A, Fisher, A, Sikaroodi, M, Rangwala, H, Gillevet, P.M
Published in Journal of hepatology (01.04.2013)
Published in Journal of hepatology (01.04.2013)
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Journal Article
Effects of CYP7A1 overexpression on cholesterol and bile acid homeostasis
Pandak, W M, Schwarz, C, Hylemon, P B, Mallonee, D, Valerie, K, Heuman, D M, Fisher, R A, Redford, K, Vlahcevic, Z R
Published in American journal of physiology: Gastrointestinal and liver physiology (01.10.2001)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.10.2001)
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A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes
Park, J S, Qiao, L, Gilfor, D, Yang, M Y, Hylemon, P B, Benz, C, Darlington, G, Firestone, G, Fisher, P B, Dent, P
Published in Molecular biology of the cell (01.09.2000)
Published in Molecular biology of the cell (01.09.2000)
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Journal Article
LXRα is the dominant regulator of CYP7A1 transcription
Gupta, Seema, Pandak, William M, Hylemon, Phillip B
Published in Biochemical and biophysical research communications (26.04.2002)
Published in Biochemical and biophysical research communications (26.04.2002)
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151 URINARY MAGNETIC RESONANCE SPECTROSCOPY IN PATIENTS WITH HEPATIC ENCEPHALOPATHY: CITRATE CORRELATES WITH ASYMMETRIC DIMETHYLARGININE AND GUT MICROBIAL SPECIES AND CAN PREDICT RECURRENCE AFTER LACTULOSE DISCONTINUATION
Bajaj, J, McPhail, M.J, Heuman, D.M, Bell, D, Gillevet, P, Sikaroodi, M, Sanyal, A.J, Sharif, M.I, Ridlon, J, Hylemon, P, Taylor-Robinson, S
Published in Journal of hepatology (2010)
Published in Journal of hepatology (2010)
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P456 SYSTEMS BIOLOGY ANALYSIS OF PROBIOTIC LACTOBACILLUS GG IN CIRRHOTIC PATIENTS WITH MINIMAL HEPATIC ENCEPHALOPATHY: A RANDOMIZED DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
Bajaj, J.S, Heuman, D, Hylemon, P, Sanyal, A, Sterling, R, Stravitz, R, Puri, P, Sikaroodi, M, Thacker, L.R, Wade, J, Gillevet, P.M
Published in Journal of hepatology (01.04.2014)
Published in Journal of hepatology (01.04.2014)
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