Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies
Gao, Feng, Bonsignori, Mattia, Liao, Hua-Xin, Kumar, Amit, Xia, Shi-Mao, Lu, Xiaozhi, Cai, Fangping, Hwang, Kwan-Ki, Song, Hongshuo, Zhou, Tongqing, Lynch, Rebecca M., Alam, S. Munir, Moody, M. Anthony, Ferrari, Guido, Berrong, Mark, Kelsoe, Garnett, Shaw, George M., Hahn, Beatrice H., Montefiori, David C., Kamanga, Gift, Cohen, Myron S., Hraber, Peter, Kwong, Peter D., Korber, Bette T., Mascola, John R., Kepler, Thomas B., Haynes, Barton F.
Published in Cell (31.07.2014)
Published in Cell (31.07.2014)
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Aberrant B cell repertoire selection associated with HIV neutralizing antibody breadth
Roskin, Krishna M, Jackson, Katherine J L, Lee, Ji-Yeun, Hoh, Ramona A, Joshi, Shilpa A, Hwang, Kwan-Ki, Bonsignori, Mattia, Pedroza-Pacheco, Isabela, Liao, Hua-Xin, Moody, M Anthony, Fire, Andrew Z, Borrow, Persephone, Haynes, Barton F, Boyd, Scott D
Published in Nature immunology (01.02.2020)
Published in Nature immunology (01.02.2020)
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Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family
BONSIGNORI, Mattia, POLLARA, Justin, MARSHALL, Dawn J, WHITESIDES, John F, TSAO, Chun-Yen, KAEWKUNGWAL, Jaranit, NITAYAPHAN, Sorachai, PITISUTTITHUM, Punnee, RERKS-NGARM, Supachai, KIM, Jerome H, MICHAEL, Nelson L, TOMARAS, Georgia D, MOODY, M. Anthony, MONTEFIORI, David C, LEWIS, George K, DEVICO, Anthony, EVANS, David T, FERRARI, Guido, LIAO, Hua-Xin, HAYNES, Barton F, ALPERT, Michael D, XI CHEN, HWANG, Kwan-Ki, GILBERT, Peter B, YING HUANG, GURLEY, Thaddeus C, KOZINK, Daniel M
Published in Journal of Virology (01.11.2012)
Published in Journal of Virology (01.11.2012)
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HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities
Pollara, Justin, Bonsignori, Mattia, Moody, M Anthony, Liu, Pinghuang, Alam, S Munir, Hwang, Kwan-Ki, Gurley, Thaddeus C, Kozink, Daniel M, Armand, Lawrence C, Marshall, Dawn J, Whitesides, John F, Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Robb, Merlin L, O'Connell, Robert J, Kim, Jerome H, Michael, Nelson L, Montefiori, David C, Tomaras, Georgia D, Liao, Hua-Xin, Haynes, Barton F, Ferrari, Guido
Published in Journal of virology (01.07.2014)
Published in Journal of virology (01.07.2014)
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Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors
BONSIGNORI, Mattia, HWANG, Kwan-Ki, SINANGIL, Faruk, PANCERA, Marie, YONGPING, Yang, ZHANG, Baoshan, JIANG ZHU, KWONG, Peter D, O'DELL, Sijy, MASCOLA, John R, LAN WU, NABEL, Gary J, XI CHEN, PHOGAT, Sanjay, SEAMAN, Michael S, WHITESIDES, John F, ANTHONY MOODY, M, KELSOE, Garnett, XINZHEN YANG, SODROSKI, Joseph, SHAW, George M, MONTEFIORI, David C, KEPLER, Thomas B, TSAO, Chun-Yen, TOMARAS, Georgia D, MUNIR ALAM, S, LIAO, Hua-Xin, HAYNES, Barton F, MORRIS, Lynn, GRAY, Elin, MARSHALL, Dawn J, CRUMP, John A, KAPIGA, Saidi H, SAM, Noel E
Published in Journal of Virology (01.10.2011)
Published in Journal of Virology (01.10.2011)
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Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier
Bonsignori, Mattia, Scott, Eric, Wiehe, Kevin, Easterhoff, David, Alam, S. Munir, Hwang, Kwan-Ki, Cooper, Melissa, Xia, Shi-Mao, Zhang, Ruijun, Montefiori, David C., Henderson, Rory, Nie, Xiaoyan, Kelsoe, Garnett, Moody, M. Anthony, Chen, Xuejun, Joyce, M. Gordon, Kwong, Peter D., Connors, Mark, Mascola, John R., McGuire, Andrew T., Stamatatos, Leonidas, Medina-Ramírez, Max, Sanders, Rogier W., Saunders, Kevin O., Kepler, Thomas B., Haynes, Barton F.
Published in Immunity (Cambridge, Mass.) (18.12.2018)
Published in Immunity (Cambridge, Mass.) (18.12.2018)
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Two Distinct Broadly Neutralizing Antibody Specificities of Different Clonal Lineages in a Single HIV-1-Infected Donor: Implications for Vaccine Design
BONSIGNORI, Mattia, MONTEFIORI, David C, KAPIGA, Saidi H, SAM, Noel E, KWONG, Peter D, KEPLER, Thomas B, LIAO, Hua-Xin, MASCOLA, John R, HAYNES, Barton F, XUELING WU, XI CHEN, HWANG, Kwan-Ki, TSAO, Chun-Yen, KOZINK, Daniel M, PARKS, Robert J, TOMARAS, Georgia D, CRUMP, John A
Published in Journal of Virology (01.04.2012)
Published in Journal of Virology (01.04.2012)
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An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1
Bonsignori, Mattia, Wiehe, Kevin, Grimm, Sebastian K, Lynch, Rebecca, Yang, Guang, Kozink, Daniel M, Perrin, Florence, Cooper, Abby J, Hwang, Kwan-Ki, Chen, Xi, Liu, Mengfei, McKee, Krisha, Parks, Robert J, Eudailey, Joshua, Wang, Minyue, Clowse, Megan, Criscione-Schreiber, Lisa G, Moody, M Anthony, Ackerman, Margaret E, Boyd, Scott D, Gao, Feng, Kelsoe, Garnett, Verkoczy, Laurent, Tomaras, Georgia D, Liao, Hua-Xin, Kepler, Thomas B, Montefiori, David C, Mascola, John R, Haynes, Barton F
Published in The Journal of clinical investigation (01.04.2014)
Published in The Journal of clinical investigation (01.04.2014)
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Antigenicity and Immunogenicity of RV144 Vaccine AIDSVAX Clade E Envelope Immunogen Is Enhanced by a gp120 N-Terminal Deletion
Alam, S Munir, Liao, Hua-Xin, Tomaras, Georgia D, Bonsignori, Mattia, Tsao, Chun-Yen, Hwang, Kwan-Ki, Chen, Haiyan, Lloyd, Krissey E, Bowman, Cindy, Sutherland, Laura, Jeffries, Jr, Thomas L, Kozink, Daniel M, Stewart, Shelley, Anasti, Kara, Jaeger, Frederick H, Parks, Robert, Yates, Nicole L, Overman, R Glenn, Sinangil, Faruk, Berman, Phillip W, Pitisuttithum, Punnee, Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Karasavva, Nicos, Rerks-Ngarm, Supachai, Kim, Jerome H, Michael, Nelson L, Zolla-Pazner, Susan, Santra, Sampa, Letvin, Norman L, Harrison, Stephen C, Haynes, Barton F
Published in Journal of Virology (01.02.2013)
Published in Journal of Virology (01.02.2013)
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High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies
Liao, Hua-Xin, Levesque, Marc C., Nagel, Ashleigh, Dixon, Ashlyn, Zhang, Ruijun, Walter, Emmanuel, Parks, Robert, Whitesides, John, Marshall, Dawn J., Hwang, Kwan-Ki, Yang, Yi, Chen, Xi, Gao, Feng, Munshaw, Supriya, Kepler, Thomas B., Denny, Thomas, Moody, M. Anthony, Haynes, Barton F.
Published in Journal of virological methods (01.06.2009)
Published in Journal of virological methods (01.06.2009)
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IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria
Hwang, Kwan-Ki, Trama, Ashley M, Kozink, Daniel M, Chen, Xi, Wiehe, Kevin, Cooper, Abby J, Xia, Shi-Mao, Wang, Minyue, Marshall, Dawn J, Whitesides, John, Alam, Munir, Tomaras, Georgia D, Allen, Steven L, Rai, Kanti R, McKeating, Jane, Catera, Rosa, Yan, Xiao-Jie, Chu, Charles C, Kelsoe, Garnett, Liao, Hua-Xin, Chiorazzi, Nicholas, Haynes, Barton F
Published in PloS one (10.03.2014)
Published in PloS one (10.03.2014)
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A human monoclonal antiprothrombin antibody is thrombogenic in vivo and upregulates expression of tissue factor and E‐selectin on endothelial cells
Vega‐Ostertag, Mariano, Liu, Xiaowei, Kwan‐Ki, Hwang, Chen, Pojen, Pierangeli, Silvia
Published in British journal of haematology (01.10.2006)
Published in British journal of haematology (01.10.2006)
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Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
Bonsignori, Mattia, Zhou, Tongqing, Sheng, Zizhang, Chen, Lei, Gao, Feng, Joyce, M. Gordon, Ozorowski, Gabriel, Chuang, Gwo-Yu, Schramm, Chaim A., Wiehe, Kevin, Alam, S. Munir, Bradley, Todd, Gladden, Morgan A., Hwang, Kwan-Ki, Iyengar, Sheelah, Kumar, Amit, Lu, Xiaozhi, Luo, Kan, Mangiapani, Michael C., Parks, Robert J., Song, Hongshuo, Acharya, Priyamvada, Bailer, Robert T., Cao, Allen, Druz, Aliaksandr, Georgiev, Ivelin S., Kwon, Young D., Louder, Mark K., Zhang, Baoshan, Zheng, Anqi, Hill, Brenna J., Kong, Rui, Soto, Cinque, Mullikin, James C., Douek, Daniel C., Montefiori, David C., Moody, Michael A., Shaw, George M., Hahn, Beatrice H., Kelsoe, Garnett, Hraber, Peter T., Korber, Bette T., Boyd, Scott D., Fire, Andrew Z., Kepler, Thomas B., Shapiro, Lawrence, Ward, Andrew B., Mascola, John R., Liao, Hua-Xin, Kwong, Peter D., Haynes, Barton F.
Published in Cell (07.04.2016)
Published in Cell (07.04.2016)
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Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee
Nicely, Nathan I., Wiehe, Kevin, Kepler, Thomas B., Jaeger, Frederick H., Dennison, S. Moses, Rerks-Ngarm, Supachai, Nitayaphan, Sorachai, Pitisuttithum, Punnee, Kaewkungwal, Jaranit, Robb, Merlin L., O'Connell, Robert J., Michael, Nelson L., Kim, Jerome H., Liao, Hua-Xin, Munir Alam, S., Hwang, Kwan-Ki, Bonsignori, Mattia, Haynes, Barton F.
Published in EBioMedicine (01.07.2015)
Published in EBioMedicine (01.07.2015)
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Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2
Liao, Hua-Xin, Bonsignori, Mattia, Alam, S. Munir, McLellan, Jason S., Tomaras, Georgia D., Moody, M. Anthony, Kozink, Daniel M., Hwang, Kwan-Ki, Chen, Xi, Tsao, Chun-Yen, Liu, Pinghuang, Lu, Xiaozhi, Parks, Robert J., Montefiori, David C., Ferrari, Guido, Pollara, Justin, Rao, Mangala, Peachman, Kristina K., Santra, Sampa, Letvin, Norman L., Karasavvas, Nicos, Yang, Zhi-Yong, Dai, Kaifan, Pancera, Marie, Gorman, Jason, Wiehe, Kevin, Nicely, Nathan I., Rerks-Ngarm, Supachai, Nitayaphan, Sorachai, Kaewkungwal, Jaranit, Pitisuttithum, Punnee, Tartaglia, James, Sinangil, Faruk, Kim, Jerome H., Michael, Nelson L., Kepler, Thomas B., Kwong, Peter D., Mascola, John R., Nabel, Gary J., Pinter, Abraham, Zolla-Pazner, Susan, Haynes, Barton F.
Published in Immunity (Cambridge, Mass.) (24.01.2013)
Published in Immunity (Cambridge, Mass.) (24.01.2013)
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Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies
Bonsignori, Mattia, Kreider, Edward F, Fera, Daniela, Meyerhoff, R Ryan, Bradley, Todd, Wiehe, Kevin, Alam, S Munir, Aussedat, Baptiste, Walkowicz, William E, Hwang, Kwan-Ki, Saunders, Kevin O, Zhang, Ruijun, Gladden, Morgan A, Monroe, Anthony, Kumar, Amit, Xia, Shi-Mao, Cooper, Melissa, Louder, Mark K, McKee, Krisha, Bailer, Robert T, Pier, Brendan W, Jette, Claudia A, Kelsoe, Garnett, Williams, Wilton B, Morris, Lynn, Kappes, John, Wagh, Kshitij, Kamanga, Gift, Cohen, Myron S, Hraber, Peter T, Montefiori, David C, Trama, Ashley, Liao, Hua-Xin, Kepler, Thomas B, Moody, M Anthony, Gao, Feng, Danishefsky, Samuel J, Mascola, John R, Shaw, George M, Hahn, Beatrice H, Harrison, Stephen C, Korber, Bette T, Haynes, Barton F
Published in Science translational medicine (15.03.2017)
Published in Science translational medicine (15.03.2017)
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Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10
Chen, Yao, Zhang, Jinsong, Hwang, Kwan-Ki, Bouton-Verville, Hilary, Xia, Shi-Mao, Newman, Amanda, Ouyang, Ying-Bin, Haynes, Barton F, Verkoczy, Laurent
Published in The Journal of immunology (1950) (01.08.2013)
Published in The Journal of immunology (1950) (01.08.2013)
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Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth
Roark, Ryan S, Li, Hui, Williams, Wilton B, Chug, Hema, Mason, Rosemarie D, Gorman, Jason, Wang, Shuyi, Lee, Fang-Hua, Rando, Juliette, Bonsignori, Mattia, Hwang, Kwan-Ki, Saunders, Kevin O, Wiehe, Kevin, Moody, M Anthony, Hraber, Peter T, Wagh, Kshitij, Giorgi, Elena E, Russell, Ronnie M, Bibollet-Ruche, Frederic, Liu, Weimin, Connell, Jesse, Smith, Andrew G, DeVoto, Julia, Murphy, Alexander I, Smith, Jessica, Ding, Wenge, Zhao, Chengyan, Chohan, Neha, Okumura, Maho, Rosario, Christina, Ding, Yu, Lindemuth, Emily, Bauer, Anya M, Bar, Katharine J, Ambrozak, David, Chao, Cara W, Chuang, Gwo-Yu, Geng, Hui, Lin, Bob C, Louder, Mark K, Nguyen, Richard, Zhang, Baoshan, Lewis, Mark G, Raymond, Donald D, Doria-Rose, Nicole A, Schramm, Chaim A, Douek, Daniel C, Roederer, Mario, Kepler, Thomas B, Kelsoe, Garnett, Mascola, John R, Kwong, Peter D, Korber, Bette T, Harrison, Stephen C, Haynes, Barton F, Hahn, Beatrice H, Shaw, George M
Published in Science (American Association for the Advancement of Science) (08.01.2021)
Published in Science (American Association for the Advancement of Science) (08.01.2021)
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A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization
Singh, Tulika, Hwang, Kwan-Ki, Miller, Andrew S., Jones, Rebecca L., Lopez, Cesar A., Dulson, Sarah J., Giuberti, Camila, Gladden, Morgan A., Miller, Itzayana, Webster, Helen S., Eudailey, Joshua A., Luo, Kan, Von Holle, Tarra, Edwards, Robert J., Valencia, Sarah, Burgomaster, Katherine E., Zhang, Summer, Mangold, Jesse F., Tu, Joshua J., Dennis, Maria, Alam, S. Munir, Premkumar, Lakshmanane, Dietze, Reynaldo, Pierson, Theodore C., Ooi, Eng Eong, Lazear, Helen M., Kuhn, Richard J., Permar, Sallie R., Bonsignori, Mattia
Published in Cell (08.12.2022)
Published in Cell (08.12.2022)
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Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated
Liao, Hua-Xin, Chen, Xi, Munshaw, Supriya, Zhang, Ruijun, Marshall, Dawn J, Vandergrift, Nathan, Whitesides, John F, Lu, Xiaozhi, Yu, Jae-Sung, Hwang, Kwan-Ki, Gao, Feng, Markowitz, Martin, Heath, Sonya L, Bar, Katharine J, Goepfert, Paul A, Montefiori, David C, Shaw, George C, Alam, S Munir, Margolis, David M, Denny, Thomas N, Boyd, Scott D, Marshal, Eleanor, Egholm, Michael, Simen, Birgitte B, Hanczaruk, Bozena, Fire, Andrew Z, Voss, Gerald, Kelsoe, Garnett, Tomaras, Georgia D, Moody, M Anthony, Kepler, Thomas B, Haynes, Barton F
Published in The Journal of experimental medicine (24.10.2011)
Published in The Journal of experimental medicine (24.10.2011)
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