Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling
Weir, Heather J., Yao, Pallas, Huynh, Frank K., Escoubas, Caroline C., Goncalves, Renata L., Burkewitz, Kristopher, Laboy, Raymond, Hirschey, Matthew D., Mair, William B.
Published in Cell metabolism (05.12.2017)
Published in Cell metabolism (05.12.2017)
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Journal Article
Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal
Burkewitz, Kristopher, Morantte, Ianessa, Weir, Heather J.M., Yeo, Robin, Zhang, Yue, Huynh, Frank K., Ilkayeva, Olga R., Hirschey, Matthew D., Grant, Ana R., Mair, William B.
Published in Cell (26.02.2015)
Published in Cell (26.02.2015)
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Journal Article
SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα
Naiman, Shoshana, Huynh, Frank K., Gil, Reuven, Glick, Yair, Shahar, Yael, Touitou, Noga, Nahum, Liat, Avivi, Matan Y., Roichman, Asael, Kanfi, Yariv, Gertler, Asaf A., Doniger, Tirza, Ilkayeva, Olga R., Abramovich, Ifat, Yaron, Orly, Lerrer, Batia, Gottlieb, Eyal, Harris, Robert A., Gerber, Doron, Hirschey, Matthew D., Cohen, Haim Y.
Published in Cell reports (Cambridge) (17.12.2019)
Published in Cell reports (Cambridge) (17.12.2019)
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Journal Article
Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH
Madsen, Andreas S., Andersen, Christian, Daoud, Mohammad, Anderson, Kristin A., Laursen, Jonas S., Chakladar, Saswati, Huynh, Frank K., Colaço, Ana R., Backos, Donald S., Fristrup, Peter, Hirschey, Matthew D., Olsen, Christian A.
Published in The Journal of biological chemistry (25.03.2016)
Published in The Journal of biological chemistry (25.03.2016)
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Journal Article
The role of leptin in glucose homeostasis
Denroche, Heather C, Huynh, Frank K, Kieffer, Timothy J
Published in Journal of diabetes investigation (01.04.2012)
Published in Journal of diabetes investigation (01.04.2012)
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Journal Article
A role for hepatic leptin signaling in lipid metabolism via altered very low density lipoprotein composition and liver lipase activity in mice
Huynh, Frank K., Neumann, Ursula H., Wang, Ying, Rodrigues, Brian, Kieffer, Timothy J., Covey, Scott D.
Published in Hepatology (Baltimore, Md.) (01.02.2013)
Published in Hepatology (Baltimore, Md.) (01.02.2013)
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Journal Article
AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells
Tudurí, Eva, Glavas, Maria M., Asadi, Ali, Baker, Robert K., Ellis, Cara E., Soukhatcheva, Galina, Philit, Marjolaine, Huynh, Frank K., Johnson, James D., Bruce Verchere, C., Kieffer, Timothy J.
Published in Scientific reports (25.07.2019)
Published in Scientific reports (25.07.2019)
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Journal Article
Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance
HUYNH, Frank K, LEVI, Jasna, DENROCHE, Heather C, GRAY, Sarah L, VOSHOL, Peter J, NEUMANN, Ursula H, SPECK, Madeleine, CHUA, Streamson C, COVEY, Scott D, KIEFFER, Timothy J
Published in Diabetes (New York, N.Y.) (01.12.2010)
Published in Diabetes (New York, N.Y.) (01.12.2010)
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Journal Article
Acute Disruption of Leptin Signaling in Vivo Leads to Increased Insulin Levels and Insulin Resistance
Levi, Jasna, Gray, Sarah L, Speck, Madeleine, Huynh, Frank K, Babich, Sandra L, Gibson, William T, Kieffer, Timothy J
Published in Endocrinology (Philadelphia) (01.09.2011)
Published in Endocrinology (Philadelphia) (01.09.2011)
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Journal Article
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion
Anderson, Kristin A, Huynh, Frank K, Fisher-Wellman, Kelsey, Stuart, J Darren, Peterson, Brett S, Douros, Jonathan D, Wagner, Gregory R, Thompson, J Will, Madsen, Andreas S, Green, Michelle F, Sivley, R Michael, Ilkayeva, Olga R, Stevens, Robert D, Backos, Donald S, Capra, John A, Olsen, Christian A, Campbell, Jonathan E, Muoio, Deborah M, Grimsrud, Paul A, Hirschey, Matthew D
Published in Cell metabolism (04.04.2017)
Published in Cell metabolism (04.04.2017)
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Journal Article
SnapShot: Mammalian Sirtuins
Anderson, Kristin A, Green, Michelle F, Huynh, Frank K, Wagner, Gregory R, Hirschey, Matthew D
Published in Cell (06.11.2014)
Published in Cell (06.11.2014)
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Journal Article
Leptin Therapy Reverses Hyperglycemia in Mice With Streptozotocin-Induced Diabetes, Independent of Hepatic Leptin Signaling
DENROCHE, Heather C, LEVI, Jasna, WIDEMAN, Rhonda D, SEQUEIRA, Roveena M, HUYNH, Frank K, COVEY, Scott D, KIEFFER, Timothy J
Published in Diabetes (New York, N.Y.) (01.05.2011)
Published in Diabetes (New York, N.Y.) (01.05.2011)
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Journal Article
Loss of sirtuin 4 leads to elevated glucose- and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds
Huynh, Frank K., Hu, Xiaoke, Lin, Zhihong, Johnson, James D., Hirschey, Matthew D.
Published in Journal of inherited metabolic disease (01.01.2018)
Published in Journal of inherited metabolic disease (01.01.2018)
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Journal Article
SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control
Huynh, Frank K, Muoio, Deborah M, Hirschey, Matthew D
Published in Diabetes (New York, N.Y.) (01.09.2015)
Published in Diabetes (New York, N.Y.) (01.09.2015)
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Journal Article
Quantifying Competition among Mitochondrial Protein Acylation Events Induced by Ethanol Metabolism
Ali, Hadi R, Assiri, Mohammed A, Harris, Peter S, Michel, Cole R, Yun, Youngho, Marentette, John O, Huynh, Frank K, Orlicky, David J, Shearn, Colin T, Saba, Laura M, Reisdorph, Richard, Reisdorph, Nichole, Hirschey, Matthew D, Fritz, Kristofer S
Published in Journal of proteome research (05.04.2019)
Published in Journal of proteome research (05.04.2019)
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Journal Article
β-Cell-specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice
Huynh, Frank K, Peterson, Brett S, Anderson, Kristin A, Lin, Zhihong, Coakley, Aeowynn J, Llaguno, Fiara M S, Nguyen, Thi-Tina N, Campbell, Jonathan E, Stephens, Samuel B, Newgard, Christopher B, Hirschey, Matthew D
Published in American journal of physiology: endocrinology and metabolism (01.10.2020)
Published in American journal of physiology: endocrinology and metabolism (01.10.2020)
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Journal Article
Cellular energetics and mitochondrial uncoupling in canine aging
Nicholatos, Justin W., Robinette, Timothy M., Tata, Saurabh V.P., Yordy, Jennifer D., Francisco, Adam B., Platov, Michael, Yeh, Tiffany K., Ilkayeva, Olga R., Huynh, Frank K., Dokukin, Maxim, Volkov, Dmytro, Weinstein, Michael A., Boyko, Adam R., Miller, Richard A., Sokolov, Igor, Hirschey, Matthew D., Libert, Sergiy
Published in GeroScience (01.04.2019)
Published in GeroScience (01.04.2019)
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Journal Article
Adeno-associated Virus (AAV) for In Vivo a– and b– Cell Gene Delivery
Tuduri, Eva, Glavas, Maria M, Baker, Robert K, Huynh, Frank K, Riedel, Michael J, Kieffer, Timothy J
Published in Canadian journal of diabetes (01.10.2012)
Published in Canadian journal of diabetes (01.10.2012)
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Journal Article