SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
Olagnier, David, Farahani, Ensieh, Thyrsted, Jacob, Blay-Cadanet, Julia, Herengt, Angela, Idorn, Manja, Hait, Alon, Hernaez, Bruno, Knudsen, Alice, Iversen, Marie Beck, Schilling, Mirjam, Jørgensen, Sofie E., Thomsen, Michelle, Reinert, Line S., Lappe, Michael, Hoang, Huy-Dung, Gilchrist, Victoria H., Hansen, Anne Louise, Ottosen, Rasmus, Nielsen, Camilla G., Møller, Charlotte, van der Horst, Demi, Peri, Suraj, Balachandran, Siddharth, Huang, Jinrong, Jakobsen, Martin, Svenningsen, Esben B., Poulsen, Thomas B., Bartsch, Lydia, Thielke, Anne L., Luo, Yonglun, Alain, Tommy, Rehwinkel, Jan, Alcamí, Antonio, Hiscott, John, Mogensen, Trine H., Paludan, Søren R., Holm, Christian K.
Published in Nature communications (02.10.2020)
Published in Nature communications (02.10.2020)
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Journal Article
Emerging translation strategies during virus-host interaction
Hoang, Huy-Dung, Neault, Serge, Pelin, Adrian, Alain, Tommy
Published in Wiley Interdisciplinary Reviews: RNA (01.01.2021)
Published in Wiley Interdisciplinary Reviews: RNA (01.01.2021)
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La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)
Fonseca, Bruno D., Zakaria, Chadi, Jia, Jian-Jun, Graber, Tyson E., Svitkin, Yuri, Tahmasebi, Soroush, Healy, Danielle, Hoang, Huy-Dung, Jensen, Jacob M., Diao, Ilo T., Lussier, Alexandre, Dajadian, Christopher, Padmanabhan, Niranjan, Wang, Walter, Matta-Camacho, Edna, Hearnden, Jaclyn, Smith, Ewan M., Tsukumo, Yoshinori, Yanagiya, Akiko, Morita, Masahiro, Petroulakis, Emmanuel, González, Jose L., Hernández, Greco, Alain, Tommy, Damgaard, Christian K.
Published in The Journal of biological chemistry (26.06.2015)
Published in The Journal of biological chemistry (26.06.2015)
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Journal Article
miR-223 Exerts Translational Control of Proatherogenic Genes in Macrophages
Nguyen, My-Anh, Hoang, Huy-Dung, Rasheed, Adil, Duchez, Anne-Claire, Wyatt, Hailey, Lynn Cottee, Mary, Graber, Tyson E, Susser, Leah, Robichaud, Sabrina, Berber, İbrahim, Geoffrion, Michele, Ouimet, Mireille, Kazan, Hilal, Maegdefessel, Lars, Mulvihill, Erin E, Alain, Tommy, Rayner, Katey J
Published in Circulation research (24.06.2022)
Published in Circulation research (24.06.2022)
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Journal Article
S6K-STING interaction regulates cytosolic DNA–mediated activation of the transcription factor IRF3
Wang, Fuan, Alain, Tommy, Szretter, Kristy J, Stephenson, Kyle, Pol, Jonathan G, Atherton, Matthew J, Hoang, Huy-Dung, Fonseca, Bruno D, Zakaria, Chadi, Chen, Lan, Rangwala, Zainab, Hesch, Adam, Chan, Eva Sin Yan, Tuinman, Carly, Suthar, Mehul S, Jiang, Zhaozhao, Ashkar, Ali A, Thomas, George, Kozma, Sara C, Gale, Michael, Fitzgerald, Katherine A, Diamond, Michael S, Mossman, Karen, Sonenberg, Nahum, Wan, Yonghong, Lichty, Brian D
Published in Nature immunology (01.05.2016)
Published in Nature immunology (01.05.2016)
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Journal Article
Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies
Azad, Taha, Rezaei, Reza, Singaravelu, Ragunath, Pelin, Adrian, Boulton, Stephen, Petryk, Julia, Onsu, Kemal Alper, Martin, Nikolas T., Hoskin, Victoria, Ghahremani, Mina, Marotel, Marie, Marius, Ricardo, He, Xiaohong, Crupi, Mathieu J. F., Hoang, Huy-Dung, Nik-Akhtar, Abolfazl, Ahmadi, Mahsa, Zamani, Nika Kooshki, Golshani, Ashkan, Alain, Tommy, Greer, Peter, Ardolino, Michele, Dickinson, Bryan C., Tai, Lee-Hwa, Ilkow, Carolina S., Bell, John C.
Published in Nature communications (26.05.2023)
Published in Nature communications (26.05.2023)
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Journal Article
Modulating endoplasmic reticulum-Golgi cargo receptors for improving secretion of carrier-fused heterologous proteins in the filamentous fungus Aspergillus oryzae
Hoang, Huy-Dung, Maruyama, Jun-ichi, Kitamoto, Katsuhiko
Published in Applied and Environmental Microbiology (01.01.2015)
Published in Applied and Environmental Microbiology (01.01.2015)
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Journal Article
UPF1 Governs Synaptic Plasticity through Association with a STAU2 RNA Granule
Graber, Tyson E, Freemantle, Erika, Anadolu, Mina N, Hébert-Seropian, Sarah, MacAdam, Robyn L, Shin, Unkyung, Hoang, Huy-Dung, Alain, Tommy, Lacaille, Jean-Claude, Sossin, Wayne S
Published in The Journal of neuroscience (20.09.2017)
Published in The Journal of neuroscience (20.09.2017)
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Journal Article
High-Pressure Delivery of Oncolytic Viruses via Needle-Free Injection Preserves Therapeutic Activity
Said, Aida, Hoang, Huy-Dung, Earl, Nathalie, Xiang, Xiao, Siddiqui, Nadeem, Côté, Marceline, Alain, Tommy
Published in Cancers (30.11.2023)
Published in Cancers (30.11.2023)
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Journal Article
Quercetin induces pannexin 1 expression via an alternative transcript with a translationally active 5′ leader in rhabdomyosarcoma
Xiang, Xiao, Hoang, Huy-Dung, Gilchrist, Victoria H., Langlois, Stéphanie, Alain, Tommy, Cowan, Kyle N.
Published in Oncogenesis (New York, NY) (22.02.2022)
Published in Oncogenesis (New York, NY) (22.02.2022)
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Journal Article
Induction of an Alternative mRNA 5′ Leader Enhances Translation of the Ciliopathy Gene Inpp5e and Resistance to Oncolytic Virus Infection
Hoang, Huy-Dung, Graber, Tyson E., Jia, Jian-Jun, Vaidya, Nasana, Gilchrist, Victoria H., Xiang, Xiao, Li, Wencheng, Cowan, Kyle N., Gkogkas, Christos G., Jaramillo, Maritza, Jafarnejad, Seyed Mehdi, Alain, Tommy
Published in Cell reports (Cambridge) (17.12.2019)
Published in Cell reports (Cambridge) (17.12.2019)
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Journal Article
Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis
Zakaria, Chadi, Sean, Polen, Hoang, Huy-Dung, Leroux, Louis-Phillipe, Watson, Margaret, Workenhe, Samuel Tekeste, Hearnden, Jaclyn, Pearl, Dana, Truong, Vinh Tai, Robichaud, Nathaniel, Yanagiya, Akiko, Tahmasebi, Soroush, Jafarnejad, Seyed Mehdi, Jia, Jian-Jun, Pelin, Adrian, Diallo, Jean-Simon, Le Boeuf, Fabrice, Bell, John Cameron, Mossman, Karen Louise, Graber, Tyson Ernst, Jaramillo, Maritza, Sonenberg, Nahum, Alain, Tommy
Published in PLoS pathogens (23.08.2018)
Published in PLoS pathogens (23.08.2018)
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Journal Article
CARMAL Is a Long Non-coding RNA Locus That Regulates MFGE8 Expression
Soubeyrand, Sébastien, Nikpay, Majid, Lau, Paulina, Turner, Adam, Hoang, Huy-Dung, Alain, Tommy, McPherson, Ruth
Published in Frontiers in genetics (17.06.2020)
Published in Frontiers in genetics (17.06.2020)
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Journal Article
Adaptation of transgene mRNA translation boosts the anticancer efficacy of oncolytic HSV1
Hoang, Huy-Dung, Said, Aida, Vaidya, Nasana, Gilchrist, Victoria H, Malone, Kyle, Kabilan, Usha, Topshee, Serena, Xiang, Xiao, Yang, An-Dao, Olagnier, David, Mossman, Karen, Beug, Shawn T, Jafarnejad, Seyed Mehdi, Workenhe, Samuel T, Graber, Tyson E, Alain, Tommy
Published in Journal for immunotherapy of cancer (01.03.2023)
Published in Journal for immunotherapy of cancer (01.03.2023)
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Journal Article
Mechanisms of impairment of interferon production by SARS-CoV-2
Hoang, Huy-Dung, Naeli, Parisa, Alain, Tommy, Jafarnejad, Seyed Mehdi
Published in Biochemical Society transactions (28.06.2023)
Published in Biochemical Society transactions (28.06.2023)
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Journal Article
Battling for Ribosomes: Translational Control at the Forefront of the Antiviral Response
Hoang, Huy-Dung, Graber, Tyson E., Alain, Tommy
Published in Journal of molecular biology (06.07.2018)
Published in Journal of molecular biology (06.07.2018)
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Journal Article
Near real-time determination of B.1.1.7 in proportion to total SARS-CoV-2 viral load in wastewater using an allele-specific primer extension PCR strategy
Graber, Tyson E., Mercier, Élisabeth, Bhatnagar, Kamya, Fuzzen, Meghan, D'Aoust, Patrick M., Hoang, Huy-Dung, Tian, Xin, Towhid, Syeda Tasneem, Plaza-Diaz, Julio, Eid, Walaa, Alain, Tommy, Butler, Ainslie, Goodridge, Lawrence, Servos, Mark, Delatolla, Robert
Published in Water research (Oxford) (15.10.2021)
Published in Water research (Oxford) (15.10.2021)
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Journal Article
mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1
Jia, Jian-Jun, Lahr, Roni M, Solgaard, Michael T, Moraes, Bruno J, Pointet, Roberta, Yang, An-Dao, Celucci, Giovanna, Graber, Tyson E, Hoang, Huy-Dung, Niklaus, Marius R, Pena, Izabella A, Hollensen, Anne K, Smith, Ewan M, Chaker-Margot, Malik, Anton, Leonie, Dajadian, Christopher, Livingstone, Mark, Hearnden, Jaclyn, Wang, Xu-Dong, Yu, Yonghao, Maier, Timm, Damgaard, Christian K, Berman, Andrea J, Alain, Tommy, Fonseca, Bruno D
Published in Nucleic acids research (06.04.2021)
Published in Nucleic acids research (06.04.2021)
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Journal Article
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
Kurmasheva, Naziia, Said, Aida, Wong, Boaz, Kinderman, Priscilla, Han, Xiaoying, Rahimic, Anna H. F., Kress, Alena, Carter-Timofte, Madalina E., Holm, Emilia, van der Horst, Demi, Kollmann, Christoph F., Liu, Zhenlong, Wang, Chen, Hoang, Huy-Dung, Kovalenko, Elina, Chrysopoulou, Maria, Twayana, Krishna Sundar, Ottosen, Rasmus N., Svenningsen, Esben B., Begnini, Fabio, Kiib, Anders E., Kromm, Florian E. H., Weiss, Hauke J., Di Carlo, Daniele, Muscolini, Michela, Higgins, Maureen, van der Heijden, Mirte, Bardoul, Angelina, Tong, Tong, Ozsvar, Attila, Hou, Wen-Hsien, Schack, Vivien R., Holm, Christian K., Zheng, Yunan, Ruzek, Melanie, Kalucka, Joanna, de la Vega, Laureano, Elgaher, Walid A. M., Korshoej, Anders R., Lin, Rongtuan, Hiscott, John, Poulsen, Thomas B., O’Neill, Luke A., Roy, Dominic G., Rinschen, Markus M., van Montfoort, Nadine, Diallo, Jean-Simon, Farin, Henner F., Alain, Tommy, Olagnier, David
Published in Nature communications (15.05.2024)
Published in Nature communications (15.05.2024)
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Journal Article
Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
Olagnier, David, Farahani, Ensieh, Thyrsted, Jacob, Blay-Cadanet, Julia, Herengt, Angela, Idorn, Manja, Hait, Alon, Hernaez, Bruno, Knudsen, Alice, Iversen, Marie Beck, Schilling, Mirjam, Jørgensen, Sofie E., Thomsen, Michelle, Reinert, Line S., Lappe, Michael, Hoang, Huy-Dung, Gilchrist, Victoria H., Hansen, Anne Louise, Ottosen, Rasmus, Nielsen, Camilla G., Møller, Charlotte, van der Horst, Demi, Peri, Suraj, Balachandran, Siddharth, Huang, Jinrong, Jakobsen, Martin, Svenningsen, Esben B., Poulsen, Thomas B., Bartsch, Lydia, Thielke, Anne L., Luo, Yonglun, Alain, Tommy, Rehwinkel, Jan, Alcamí, Antonio, Hiscott, John, Mogensen, Trine H., Paludan, Søren R., Holm, Christian K.
Published in Nature communications (21.10.2020)
Published in Nature communications (21.10.2020)
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