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Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates
Falcon, Benjamin, Cavallini, Annalisa, Angers, Rachel, Glover, Sarah, Murray, Tracey K., Barnham, Luanda, Jackson, Samuel, O'Neill, Michael J., Isaacs, Adrian M., Hutton, Michael L., Szekeres, Philip G., Goedert, Michel, Bose, Suchira
Published in The Journal of biological chemistry (09.01.2015)
Published in The Journal of biological chemistry (09.01.2015)
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A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice
DeMattos, Ronald B., Lu, Jirong, Tang, Ying, Racke, Margaret M., DeLong, Cindy A., Tzaferis, John A., Hole, Justin T., Forster, Beth M., McDonnell, Peter C., Liu, Feng, Kinley, Robert D., Jordan, William H., Hutton, Michael L.
Published in Neuron (Cambridge, Mass.) (06.12.2012)
Published in Neuron (Cambridge, Mass.) (06.12.2012)
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TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
Amador-Ortiz, Catalina, Lin, Wen-Lang, Ahmed, Zeshan, Personett, David, Davies, Peter, Duara, Ranjan, Graff-Radford, Neill R., Hutton, Michael L., Dickson, Dennis W.
Published in Annals of neurology (01.05.2007)
Published in Annals of neurology (01.05.2007)
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Accelerated Lipofuscinosis and Ubiquitination in Granulin Knockout Mice Suggest a Role for Progranulin in Successful Aging
Ahmed, Zeshan, Sheng, Hong, Xu, Ya-fei, Lin, Wen-Lang, Innes, Amy E., Gass, Jennifer, Yu, Xin, Hou, Harold, Chiba, Shuichi, Yamanouchi, Keitaro, Leissring, Malcolm, Petrucelli, Leonard, Nishihara, Masugi, Hutton, Michael L., McGowan, Eileen, Dickson, Dennis W., Lewis, Jada
Published in The American journal of pathology (01.07.2010)
Published in The American journal of pathology (01.07.2010)
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Astrocytes and neuroinflammation in Alzheimer's disease
Phillips, Emma C, Croft, Cara L, Kurbatskaya, Ksenia, O'Neill, Michael J, Hutton, Michael L, Hanger, Diane P, Garwood, Claire J, Noble, Wendy
Published in Biochemical Society transactions (01.10.2014)
Published in Biochemical Society transactions (01.10.2014)
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Progressive Supranuclear Palsy: Pathology and Genetics
Dickson, Dennis W., Rademakers, Rosa, Hutton, Michael L.
Published in Brain pathology (Zurich, Switzerland) (01.01.2007)
Published in Brain pathology (Zurich, Switzerland) (01.01.2007)
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Recommendations of the Alzheimer's disease-related dementias conference
Montine, Thomas J, Koroshetz, Walter J, Babcock, Debra, Dickson, Dennis W, Galpern, Wendy R, Glymour, M Maria, Greenberg, Steven M, Hutton, Michael L, Knopman, David S, Kuzmichev, Andrey N, Manly, Jennifer J, Marder, Karen S, Miller, Bruce L, Phelps, Creighton H, Seeley, William W, Sieber, Beth-Anne, Silverberg, Nina B, Sutherland, Margaret, Torborg, Christine L, Waddy, Salina P, Zlokovic, Berislav V, Corriveau, Roderick A
Published in Neurology (26.08.2014)
Published in Neurology (26.08.2014)
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Altered Synapse Stability in the Early Stages of Tauopathy
Jackson, Johanna S., Witton, Jonathan, Johnson, James D., Ahmed, Zeshan, Ward, Mark, Randall, Andrew D., Hutton, Michael L., Isaac, John T., O’Neill, Michael J., Ashby, Michael C.
Published in Cell reports (Cambridge) (28.03.2017)
Published in Cell reports (Cambridge) (28.03.2017)
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Progranulin in frontotemporal lobar degeneration and neuroinflammation
Ahmed, Zeshan, Mackenzie, Ian RA, Hutton, Michael L, Dickson, Dennis W
Published in Journal of neuroinflammation (11.02.2007)
Published in Journal of neuroinflammation (11.02.2007)
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Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia
Rademakers, Rosa, Eriksen, Jason L., Baker, Matt, Robinson, Todd, Ahmed, Zeshan, Lincoln, Sarah J., Finch, Nicole, Rutherford, Nicola J., Crook, Richard J., Josephs, Keith A., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Parisi, Joseph E., Caselli, Richard J., Wszolek, Zbigniew K., Uitti, Ryan J., Feldman, Howard, Hutton, Michael L., Mackenzie, Ian R., Graff-Radford, Neill R., Dickson, Dennis W.
Published in Human molecular genetics (01.12.2008)
Published in Human molecular genetics (01.12.2008)
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APOE ε4 lowers age at onset and is a high risk factor for Alzheimer's disease; A case control study from central Norway
Sando, Sigrid B, Melquist, Stacey, Cannon, Ashley, Hutton, Michael L, Sletvold, Olav, Saltvedt, Ingvild, White, Linda R, Lydersen, Stian, Aasly, Jan O
Published in BMC neurology (16.04.2008)
Published in BMC neurology (16.04.2008)
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Mimicking Aspects of Frontotemporal Lobar Degeneration and Lou Gehrig's Disease in Rats via TDP-43 Overexpression
Tatom, Jason B, Wang, David B, Dayton, Robert D, Skalli, Omar, Hutton, Michael L, Dickson, Dennis W, Klein, Ronald L
Published in Molecular therapy (01.04.2009)
Published in Molecular therapy (01.04.2009)
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Evidence for an association between KIBRA and late-onset Alzheimer's disease
Corneveaux, Jason J., Liang, Winnie S., Reiman, Eric M., Webster, Jennifer A., Myers, Amanda J., Zismann, Victoria L., Joshipura, Keta D., Pearson, John V., Hu-Lince, Diane, Craig, David W., Coon, Keith D., Dunckley, Travis, Bandy, Daniel, Lee, Wendy, Chen, Kewei, Beach, Thomas G., Mastroeni, Diego, Grover, Andrew, Ravid, Rivka, Sando, Sigrid B., Aasly, Jan O., Heun, Reinhard, Jessen, Frank, Kölsch, Heike, Rogers, Joseph, Hutton, Michael L., Melquist, Stacey, Petersen, Ron C., Alexander, Gene E., Caselli, Richard J., Papassotiropoulos, Andreas, Stephan, Dietrich A., Huentelman, Matthew J.
Published in Neurobiology of aging (01.06.2010)
Published in Neurobiology of aging (01.06.2010)
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Discovery and clinical translation of ceperognastat, an O‐GlcNAcase (OGA) inhibitor, for the treatment of Alzheimer's disease
Kielbasa, William, Goldsmith, Paul, Donnelly, Kevin B., Nuthall, Hugh N., Shcherbinin, Sergey, Fleisher, Adam S., Hendle, Jörg, DuBois, Susan L., Lowe, Stephen L., Zhang, Feiyu Fred, Woerly, Eric M., Dreyfus, Nicolas J.‐F., Evans, David, Gilmore, Jeremy, Mancini, Michele, Constantinescu, Cristian C., Gunn, Roger N., Russell, David S., Collins, Emily C., Brys, Miroslaw, Hutton, Michael L., Mergott, Dustin J.
Published in Alzheimer's & dementia : translational research & clinical interventions (01.10.2024)
Published in Alzheimer's & dementia : translational research & clinical interventions (01.10.2024)
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Identification of the Genetic Basis for Complex Disorders by Use of Pooling-Based Genomewide Single-Nucleotide–Polymorphism Association Studies
Pearson, John V., Huentelman, Matthew J., Halperin, Rebecca F., Tembe, Waibhav D., Melquist, Stacey, Homer, Nils, Brun, Marcel, Szelinger, Szabolcs, Coon, Keith D., Zismann, Victoria L., Webster, Jennifer A., Beach, Thomas, Sando, Sigrid B., Aasly, Jan O., Heun, Reinhard, Jessen, Frank, Kölsch, Heike, Tsolaki, Magdalini, Daniilidou, Makrina, Reiman, Eric M., Papassotiropoulos, Andreas, Hutton, Michael L., Stephan, Dietrich A., Craig, David W.
Published in American journal of human genetics (01.01.2007)
Published in American journal of human genetics (01.01.2007)
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A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity
Ahmed, Zeshan, Cooper, Jane, Murray, Tracey K., Garn, Katya, McNaughton, Emily, Clarke, Hannah, Parhizkar, Samira, Ward, Mark A., Cavallini, Annalisa, Jackson, Samuel, Bose, Suchira, Clavaguera, Florence, Tolnay, Markus, Lavenir, Isabelle, Goedert, Michel, Hutton, Michael L., O’Neill, Michael J.
Published in Acta neuropathologica (01.05.2014)
Published in Acta neuropathologica (01.05.2014)
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Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression
Chai, Xiyun, Wu, Su, Murray, Tracey K, Kinley, Robert, Cella, Claire V, Sims, Helen, Buckner, Nicola, Hanmer, Jenna, Davies, Peter, O'Neill, Michael J, Hutton, Michael L, Citron, Martin
Published in The Journal of biological chemistry (30.09.2011)
Published in The Journal of biological chemistry (30.09.2011)
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Alzheimer's Disease-Related Dementias Summit 2016: National research priorities
Corriveau, Roderick A, Koroshetz, Walter J, Gladman, Jordan T, Jeon, Sophia, Babcock, Debra, Bennett, David A, Carmichael, S Thomas, Dickinson, Susan L-J, Dickson, Dennis W, Emr, Marian, Fillit, Howard, Greenberg, Steven M, Hutton, Michael L, Knopman, David S, Manly, Jennifer J, Marder, Karen S, Moy, Claudia S, Phelps, Creighton H, Scott, Paul A, Seeley, William W, Sieber, Beth-Anne, Silverberg, Nina B, Sutherland, Margaret L, Taylor, Angela, Torborg, Christine L, Waddy, Salina P, Gubitz, Amelie K, Holtzman, David M
Published in Neurology (05.12.2017)
Published in Neurology (05.12.2017)
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Neurofibrillary tangle-related synaptic alterations of spinal motor neurons of P301L tau transgenic mice
Katsuse, Omi, Lin, Wen-Lang, Lewis, Jada, Hutton, Michael L., Dickson, Dennis W.
Published in Neuroscience letters (01.12.2006)
Published in Neuroscience letters (01.12.2006)
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Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD
Momeni, Parastoo, Schymick, Jennifer, Jain, Shushant, Cookson, Mark R, Cairns, Nigel J, Greggio, Elisa, Greenway, Matthew J, Berger, Stephen, Pickering-Brown, Stuart, Chiò, Adriano, Fung, Hon Chung, Holtzman, David M, Huey, Edward D, Wassermann, Eric M, Adamson, Jennifer, Hutton, Michael L, Rogaeva, Ekaterina, St George-Hyslop, Peter, Rothstein, Jeffrey D, Hardiman, Orla, Grafman, Jordan, Singleton, Andrew, Hardy, John, Traynor, Bryan J
Published in BMC neurology (13.12.2006)
Published in BMC neurology (13.12.2006)
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