Glucocorticoid modulation of tryptophan hydroxylase-2 protein in raphe nuclei and 5-hydroxytryptophan concentrations in frontal cortex of C57 Bl6 mice
Clark, J A, Flick, R B, Pai, L-Y, Szalayova, I, Key, S, Conley, R K, Deutch, A Y, Hutson, P H, Mezey, E
Published in Molecular psychiatry (01.05.2008)
Published in Molecular psychiatry (01.05.2008)
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The hypothermic effect of 5-CT in mice is mediated through the 5-HT7 receptor
GUSCOTT, M. R, EGAN, E, HUTSON, P. H, COOK, G. P, STANTON, J. A, BEER, M. S, ROSAHL, T. W, HARTMANN, S, KULAGOWSKI, J, MCALLISTER, G, FONE, K. C. F
Published in Neuropharmacology (01.06.2003)
Published in Neuropharmacology (01.06.2003)
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Behavioral and biochemical characterization of a mutant mouse strain lacking d-amino acid oxidase activity and its implications for schizophrenia
Almond, S.L., Fradley, R.L., Armstrong, E.J., Heavens, R.B., Rutter, A.R., Newman, R.J., Chiu, C.S, Konno, R., Hutson, P.H., Brandon, N.J.
Published in Molecular and cellular neuroscience (01.08.2006)
Published in Molecular and cellular neuroscience (01.08.2006)
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Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats
McDonald, L. M., Sheppard, W. F., Staveley, S. M., Sohal, B., Tattersall, F. D., Hutson, P. H.
Published in Psychopharmacologia (01.05.2008)
Published in Psychopharmacologia (01.05.2008)
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Current and Novel Approaches to the Drug Treatment of Schizophrenia
Rowley, Michael, Bristow, Linda J, Hutson, Peter H
Published in Journal of medicinal chemistry (15.02.2001)
Published in Journal of medicinal chemistry (15.02.2001)
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CNS Target Identification and Validation: Avoiding the Valley of Death or Naive Optimism?
Hutson, P.H, Clark, J.A, Cross, A.J
Published in Annual review of pharmacology and toxicology (06.01.2017)
Published in Annual review of pharmacology and toxicology (06.01.2017)
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The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents
Hutson, P H, Finger, E N, Magliaro, B C, Smith, S M, Converso, A, Sanderson, P E, Mullins, D, Hyde, L A, Eschle, B K, Turnbull, Z, Sloan, H, Guzzi, M, Zhang, X, Wang, A, Rindgen, D, Mazzola, R, Vivian, J A, Eddins, D, Uslaner, J M, Bednar, R, Gambone, C, Le-Mair, W, Marino, M J, Sachs, N, Xu, G, Parmentier-Batteur, S
Published in Neuropharmacology (01.09.2011)
Published in Neuropharmacology (01.09.2011)
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Determination of guinea-pig cortical γ-secretase activity ex vivo following the systemic administration of a γ-secretase inhibitor
Grimwood, S., Hogg, J., Jay, M.T., Lad, A.M., Lee, V., Murray, F., Peachey, J., Townend, T., Vithlani, M., Beher, D., Shearman, M.S., Hutson, P.H.
Published in Neuropharmacology (01.06.2005)
Published in Neuropharmacology (01.06.2005)
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The glycine/NMDA receptor antagonist, R‐(+)‐HA‐966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK‐801) in rodents
Bristow, L.J., Hutson, P.H., Thorn, L., Tricklebank, M.D.
Published in British journal of pharmacology (01.04.1993)
Published in British journal of pharmacology (01.04.1993)
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Enantiomers of HA-966 (3-Amino-1-Hydroxypyrrolid-2-One) Exhibit Distinct Central Nervous System Effects: (+)-HA-966 is a Selective Glycine/N- Methyl-D-Aspartate Receptor Antagonist, But (-)-HA-966 is a Potent γ-Butyrolactone-Like Sedative
Singh, L., Donald, A. E., Foster, A. C., Hutson, P. H., Iversen, L. L., Iversen, S. D., Kemp, J. A., Leeson, P. D., Marshall, G. R., Oles, R. J., Priestley, T., Thorn, L., Tricklebank, M. D., Vass, C. A., Williams, B. J.
Published in Proceedings of the National Academy of Sciences - PNAS (01.01.1990)
Published in Proceedings of the National Academy of Sciences - PNAS (01.01.1990)
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