Structural insights into µ-opioid receptor activation
Huang, Weijiao, Manglik, Aashish, Venkatakrishnan, A J, Laeremans, Toon, Feinberg, Evan N, Sanborn, Adrian L, Kato, Hideaki E, Livingston, Kathryn E, Thorsen, Thor S, Kling, Ralf C, Granier, Sébastien, Gmeiner, Peter, Husbands, Stephen M, Traynor, John R, Weis, William I, Steyaert, Jan, Dror, Ron O, Kobilka, Brian K
Published in Nature (London) (20.08.2015)
Published in Nature (London) (20.08.2015)
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Methocinnamox (MCAM) antagonizes the behavioral suppressant effects of morphine without impairing delayed matching-to-sample accuracy in rhesus monkeys
Minervini, Vanessa, Disney, Alex, Husbands, Stephen M., France, Charles P.
Published in Psychopharmacology (01.10.2020)
Published in Psychopharmacology (01.10.2020)
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A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates
Ding, Huiping, Czoty, Paul W., Kiguchi, Norikazu, Cami-Kobeci, Gerta, Sukhtankar, Devki D., Nader, Michael A., Husbands, Stephen M., Ko, Mei-Chuan
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.2016)
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Antidepressant‐like effects of BU10119, a novel buprenorphine analogue with mixed κ/μ receptor antagonist properties, in mice
Almatroudi, Abdulrahman, Ostovar, Mehrnoosh, Bailey, Christopher P, Husbands, Stephen M, Bailey, Sarah J
Published in British journal of pharmacology (01.07.2018)
Published in British journal of pharmacology (01.07.2018)
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Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys
Maguire, David R, Gerak, Lisa R, Sanchez, Jesus J, Javors, Martin A, Disney, Alex, Husbands, Stephen M, France, Charles P
Published in Neuropsychopharmacology (New York, N.Y.) (01.11.2020)
Published in Neuropsychopharmacology (New York, N.Y.) (01.11.2020)
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A novel G protein‐biased agonist at the μ opioid receptor induces substantial receptor desensitisation through G protein‐coupled receptor kinase
Groom, Sam, Blum, Nina K., Conibear, Alexandra E., Disney, Alexander, Hill, Rob, Husbands, Stephen M., Li, Yangmei, Toll, Lawrence, Kliewer, Andrea, Schulz, Stefan, Henderson, Graeme, Kelly, Eamonn, Bailey, Chris P.
Published in British journal of pharmacology (01.04.2023)
Published in British journal of pharmacology (01.04.2023)
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Countermeasures for Preventing and Treating Opioid Overdose
France, Charles P, Ahern, Gerard P, Averick, Saadyah, Disney, Alex, Enright, Heather A, Esmaeli-Azad, Babak, Federico, Arianna, Gerak, Lisa R, Husbands, Stephen M, Kolber, Benedict, Lau, Edmond Y, Lao, Victoria, Maguire, David R, Malfatti, Michael A, Martinez, Girardo, Mayer, Brian P, Pravetoni, Marco, Sahibzada, Niaz, Skolnick, Phil, Snyder, Evan Y, Tomycz, Nestor, Valdez, Carlos A, Zapf, Jim
Published in Clinical pharmacology and therapeutics (01.03.2021)
Published in Clinical pharmacology and therapeutics (01.03.2021)
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Reversal and Prevention of the Respiratory-Depressant Effects of Heroin by the Novel μ -Opioid Receptor Antagonist Methocinnamox in Rhesus Monkeys
Gerak, Lisa R, Maguire, David R, Woods, James H, Husbands, Stephen M, Disney, Alex, France, Charles P
Published in The Journal of pharmacology and experimental therapeutics (01.02.2019)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2019)
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Synthetic Cannabinoid Receptor Agonists Detection Using Fluorescence Spectral Fingerprinting
May, Benedict, Naqi, Husain A, Tipping, Michael, Scott, Jenny, Husbands, Stephen M, Blagbrough, Ian S, Pudney, Christopher R
Published in Analytical chemistry (Washington) (15.10.2019)
Published in Analytical chemistry (Washington) (15.10.2019)
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Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/μ-opioid receptor ligands in mouse models of neuropathic and inflammatory pain
Sukhtankar, Devki D, Zaveri, Nurulain T, Husbands, Stephen M, Ko, Mei-Chuan
Published in The Journal of pharmacology and experimental therapeutics (01.07.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2013)
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Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ -Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats
Gerak, Lisa R, Minervini, Vanessa, Latham, Elizabeth, Ghodrati, Saba, Lillis, Katherine V, Wooden, Jessica, Disney, Alex, Husbands, Stephen M, France, Charles P
Published in The Journal of pharmacology and experimental therapeutics (01.11.2019)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2019)
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The Buprenorphine Analogue BU10119 Attenuates Drug-Primed and Stress-Induced Cocaine Reinstatement in Mice
Hillhouse, Todd M, Olson, Keith M, Hallahan, James E, Rysztak, Lauren G, Sears, Bryan F, Meurice, Claire, Ostovar, Mehrnoosh, Koppenhaver, Peyton O, West, Joshua L, Jutkiewicz, Emily M, Husbands, Stephen M, Traynor, John R
Published in The Journal of pharmacology and experimental therapeutics (01.09.2021)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2021)
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Journal Article
OREX-1019: A Novel Treatment of Opioid Use Disorder and Relapse Prevention
Maguire, David R, Gerak, Lisa R, Cami-Kobeci, Gerta, Husbands, Stephen M, France, Charles P, Belli, Barbara, Flynn, Peter
Published in The Journal of pharmacology and experimental therapeutics (01.02.2020)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2020)
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