Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism
Marcotte, Douglas, Zeng, Weike, Hus, Jean-Christophe, McKenzie, Andres, Hession, Cathy, Jin, Ping, Bergeron, Chris, Lugovskoy, Alexey, Enyedy, Istvan, Cuervo, Hernan, Wang, Deping, Atmanene, Cédric, Roecklin, Dominique, Vecchi, Malgorzata, Vivat, Valérie, Kraemer, Joachim, Winkler, Dirk, Hong, Victor, Chao, Jianhua, Lukashev, Matvey, Silvian, Laura
Published in Bioorganic & medicinal chemistry (15.07.2013)
Published in Bioorganic & medicinal chemistry (15.07.2013)
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Journal Article
Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine‐based inhibitor co‐crystal structure
Marcotte, Douglas J., Hus, Jean‐Christophe, Banos, Charles C., Wildes, Craig, Arduini, Robert, Bergeron, Chris, Hession, Catherine A., Baker, Darren P., Lin, Edward, Guckian, Kevin M., Dunah, Anthone W., Silvian, Laura F.
Published in Protein science (01.03.2018)
Published in Protein science (01.03.2018)
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Journal Article
Rotational Diffusion Anisotropy and Local Backbone Dynamics of Carbon Monoxide-Bound Rhodobacter capsulatus Cytochrome c
Tsan, Pascale, Hus, Jean-Christophe, Caffrey, Michael, Marion, Dominique, Blackledge, Martin
Published in Journal of the American Chemical Society (14.06.2000)
Published in Journal of the American Chemical Society (14.06.2000)
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Journal Article
16-Fold Degeneracy of Peptide Plane Orientations from Residual Dipolar Couplings: Analytical Treatment and Implications for Protein Structure Determination
Hus, Jean-Christophe, Salmon, Loïc, Bouvignies, Guillaume, Lotze, Johannes, Blackledge, Martin, Brüschweiler, Rafael
Published in Journal of the American Chemical Society (26.11.2008)
Published in Journal of the American Chemical Society (26.11.2008)
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Journal Article
Determination of Protein Backbone Structure Using Only Residual Dipolar Couplings
Hus, Jean-Christophe, Marion, Dominique, Blackledge, Martin
Published in Journal of the American Chemical Society (21.02.2001)
Published in Journal of the American Chemical Society (21.02.2001)
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Journal Article
A Methylation-Dependent Electrostatic Switch Controls DNA Repair and Transcriptional Activation by E. coli Ada
He, Chuan, Hus, Jean-Christophe, Sun, Li Jing, Zhou, Pei, Norman, Derek P.G., Dötsch, Volker, Wei, Hua, Gross, John D., Lane, William S., Wagner, Gerhard, Verdine, Gregory L.
Published in Molecular cell (07.10.2005)
Published in Molecular cell (07.10.2005)
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Journal Article
Assignment Strategy for Proteins with Known Structure
Hus, Jean-Christophe, Prompers, Jeanine J, Brüschweiler, Rafael
Published in Journal of magnetic resonance (1997) (01.07.2002)
Published in Journal of magnetic resonance (1997) (01.07.2002)
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Journal Article
HINGE-MODIFIED BISPECIFIC ANTIBODIES
HUS, Jean-Christophe, LUGOVSKOY, Alexey Alexandrovich, GEDDIE, Melissa
Year of Publication 10.10.2024
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Year of Publication 10.10.2024
Patent
BISPECIFIC AGONISTIC ANTIBODIES TO ACTIVIN A RECEPTOR LIKE TYPE 1 (ALK1)
HUS, Jean-Christophe, LUGOVSKOY, Alexey Alexandrovich, GEDDIE, Melissa
Year of Publication 10.10.2024
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Year of Publication 10.10.2024
Patent
HETEROMERIC AGONISTIC ANTIBODIES TO IL-18 RECEPTOR
Lugovskoy, Alexey Alexandrovich, Hus, Jean-Christophe, Geddie, Melissa
Year of Publication 27.06.2024
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Year of Publication 27.06.2024
Patent
HETEROMERIC AGONISTIC ANTIBODIES TO IL-18 RECEPTOR
HUS, Jean-Christophe, LUGOVSKOY, Alexey Alexandrovich, GEDDIE, Melissa
Year of Publication 25.04.2024
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Year of Publication 25.04.2024
Patent