Overt Thyroid Dysfunction and Anti-Thyroid Antibodies Predict Response to Anti-PD-1 Immunotherapy in Cancer Patients
Basak, Edwin A, van der Meer, Jan W M, Hurkmans, Daan P, Schreurs, Marco W J, Oomen-de Hoop, Esther, van der Veldt, Astrid A M, Bins, Sander, Joosse, Arjen, Koolen, Stijn L W, Debets, Reno, Peeters, Robin P, Aerts, Joachim G J V, Mathijssen, Ron H J, Medici, Marco
Published in Thyroid (New York, N.Y.) (01.07.2020)
Published in Thyroid (New York, N.Y.) (01.07.2020)
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Journal Article
Correlation between nivolumab exposure and treatment outcomes in non–small-cell lung cancer
Basak, Edwin A., Koolen, Stijn L.W., Hurkmans, Daan P., Schreurs, Marco W.J., Bins, Sander, Oomen – de Hoop, Esther, Wijkhuijs, Annemarie J.M., Besten, Ilse den, Sleijfer, Stefan, Debets, Reno, van der Veldt, Astrid A.M., Aerts, Joachim G.J.V., Mathijssen, Ron H.J.
Published in European journal of cancer (1990) (01.03.2019)
Published in European journal of cancer (1990) (01.03.2019)
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Journal Article
The prognostic value of weight and body composition changes in patients with non‐small‐cell lung cancer treated with nivolumab
Degens, Juliette H.R.J., Dingemans, Anne‐Marie C., Willemsen, Anna C.H., Gietema, Hester A., Hurkmans, Daan P., Aerts, Joachim G., Hendriks, Lizza E.L., Schols, Annemie M.W.J.
Published in Journal of cachexia, sarcopenia and muscle (01.06.2021)
Published in Journal of cachexia, sarcopenia and muscle (01.06.2021)
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Journal Article
Influence of esomeprazole on the bioavailability of afatinib: A pharmacokinetic cross-over study in patients with non-small cell lung cancer
Veerman, G.D. Marijn, Hurkmans, Daan P., Paats, Marthe S., Oomen-de Hoop, Esther, van der Leest, Cor H., van Thiel, Eric R.E., Aerts, Joachim G.J.V., van Leeuwen, Roelof W., Dingemans, Anne-Marie C., Mathijssen, Ron H.J.
Published in Biomedicine & pharmacotherapy (01.11.2022)
Published in Biomedicine & pharmacotherapy (01.11.2022)
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Journal Article
Granzyme B is correlated with clinical outcome after PD-1 blockade in patients with stage IV non-small-cell lung cancer
Hurkmans, Daan P., Basak, Edwin A., Schepers, Nina, Oomen-De Hoop, Esther, Van der Leest, Cor H., El Bouazzaoui, Samira, Bins, Sander, Koolen, Stijn L. W., Sleijfer, Stefan, Van der Veldt, Astrid A. M., Debets, Reno, Van Schaik, Ron H. N., Aerts, Joachim G. J. V., Mathijssen, Ron H. J.
Published in Journal for immunotherapy of cancer (01.05.2020)
Published in Journal for immunotherapy of cancer (01.05.2020)
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Journal Article
Molecular data show conserved DNA locations distinguishing lung cancer subtypes and regulation of immune genes
Hurkmans, Daan P., Tamminga, Menno, van Es, Bram, Peters, Tom, Karman, Wouter, van Wijck, Rogier T.A., van der Spek, Peter J., Tauber, Tjebbe, Los, Maureen, van Schetsen, Anouk, Vu, Thu, Hiltermann, T. Jeroen. N., Schuuring, Ed, Aerts, Joachim G.J.V., Chen, Sissy, Groen, Harry J.M.
Published in Lung cancer (Amsterdam, Netherlands) (01.08.2020)
Published in Lung cancer (Amsterdam, Netherlands) (01.08.2020)
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Journal Article
CD45RA + CCR7 - CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab
Kunert, Andre, Basak, Edwin A, Hurkmans, Daan P, Balcioglu, Hayri E, Klaver, Yarne, van Brakel, Mandy, Oostvogels, Astrid A M, Lamers, Cor H J, Bins, Sander, Koolen, Stijn L W, van der Veldt, Astrid A M, Sleijfer, Stefan, Mathijssen, Ron H J, Aerts, Joachim G J V, Debets, Reno
Published in Journal for immunotherapy of cancer (08.06.2019)
Published in Journal for immunotherapy of cancer (08.06.2019)
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Journal Article
Donor-derived cell-free DNA detects kidney transplant rejection during nivolumab treatment
Hurkmans, Daan P, Verhoeven, Jeroen G H P, de Leur, Kitty, Boer, Karin, Joosse, Arjen, Baan, Carla C, von der Thüsen, Jan H, van Schaik, Ron H N, Mathijssen, Ron H J, van der Veldt, Astrid A M, Hesselink, Dennis A
Published in Journal for immunotherapy of cancer (12.07.2019)
Published in Journal for immunotherapy of cancer (12.07.2019)
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Journal Article
High-intensity statins are associated with improved clinical activity of PD-1 inhibitors in malignant pleural mesothelioma and advanced non-small cell lung cancer patients
Cantini, Luca, Pecci, Federica, Hurkmans, Daan P., Belderbos, Robert A., Lanese, Andrea, Copparoni, Cecilia, Aerts, Sophie, Cornelissen, Robin, Dumoulin, Daphne W., Fiordoliva, Ilaria, Rinaldi, Silvia, Aerts, Joachim G.J.V., Berardi, Rossana
Published in European journal of cancer (1990) (01.02.2021)
Published in European journal of cancer (1990) (01.02.2021)
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Journal Article
Tumor mutational load, CD8+ T cells, expression of PD-L1 and HLA class I to guide immunotherapy decisions in NSCLC patients
Hurkmans, Daan P., Kuipers, Merian E., Smit, Jasper, van Marion, Ronald, Mathijssen, Ron H. J., Postmus, Piet E., Hiemstra, Pieter S., Aerts, Joachim G. J. V., von der Thüsen, Jan H., van der Burg, Sjoerd H.
Published in Cancer Immunology, Immunotherapy (01.05.2020)
Published in Cancer Immunology, Immunotherapy (01.05.2020)
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Journal Article
A Serum Protein Classifier Identifying Patients with Advanced Non-Small Cell Lung Cancer Who Derive Clinical Benefit from Treatment with Immune Checkpoint Inhibitors
Muller, Mirte, Hummelink, Karlijn, Hurkmans, Daan P, Niemeijer, Anna-Larissa N, Monkhorst, Kim, Roder, Joanna, Oliveira, Carlos, Roder, Heinrich, Aerts, Joachim G, Smit, Egbert F
Published in Clinical cancer research (01.10.2020)
Published in Clinical cancer research (01.10.2020)
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Journal Article
Fibrotic activity quantified in serum by measurements of type III collagen pro-peptides can be used for prognosis across different solid tumor types
Willumsen, Nicholas, Jensen, Christina, Green, George, Nissen, Neel I., Neely, Jaclyn, Nelson, David M., Pedersen, Rasmus S., Frederiksen, Peder, Chen, Inna M., Boisen, Mogens K., Johansen, Astrid Z., Madsen, Daniel H., Svane, Inge Marie, Lipton, Allan, Leitzel, Kim, Ali, Suhail M., Erler, Janine T., Hurkmans, Daan P., Mathijssen, Ron H. J., Aerts, Joachim, Eslam, Mohammed, George, Jacob, Christiansen, Claus, Bissel, Mina J., Karsdal, Morten A.
Published in Cellular and molecular life sciences : CMLS (01.04.2022)
Published in Cellular and molecular life sciences : CMLS (01.04.2022)
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Journal Article
Associations between patient and disease characteristics and severe adverse events during immune checkpoint inhibitor treatment: An observational study
Basak, Edwin A., Vermeer, Niels S., de Joode, Karlijn, Hurkmans, Daan P., Velthuis, Dorian E.M., Oomen-de Hoop, Esther, Schreurs, Marco W.J., Bins, Sander, Koolen, Stijn L.W., Debets, Reno, van der Veldt, Astrid A.M., Aerts, Joachim G.J.V., Joosse, Arjen, Mathijssen, Ron H.J.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Journal Article
Blood-based extracellular matrix biomarkers are correlated with clinical outcome after PD-1 inhibition in patients with metastatic melanoma
Hurkmans, Daan P, Jensen, Christina, Koolen, Stijn L W, Aerts, Joachim, Karsdal, Morten Asser, Mathijssen, Ron H J, Willumsen, Nicholas
Published in Journal for immunotherapy of cancer (01.10.2020)
Published in Journal for immunotherapy of cancer (01.10.2020)
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Journal Article
A prospective cohort study on the pharmacokinetics of nivolumab in metastatic non-small cell lung cancer, melanoma, and renal cell cancer patients
Hurkmans, Daan P, Basak, Edwin A, van Dijk, Tanja, Mercieca, Darlene, Schreurs, Marco W J, Wijkhuijs, Annemarie J M, Bins, Sander, Hoop, Esther Oomen-de, Debets, Reno, Joerger, Markus, Odink, Arlette, van der Veldt, Astrid A M, van der Leest, Cor H, Aerts, Joachim G J V, Mathijssen, Ron H J, Koolen, Stijn L W
Published in Journal for immunotherapy of cancer (19.07.2019)
Published in Journal for immunotherapy of cancer (19.07.2019)
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Journal Article
Germline Variation in PDCD1 Is Associated with Overall Survival in Patients with Metastatic Melanoma Treated with Anti-PD-1 Monotherapy
de With, Mirjam, Hurkmans, Daan P, Oomen-de Hoop, Esther, Lalouti, Ayoub, Bins, Sander, El Bouazzaoui, Samira, van Brakel, Mandy, Debets, Reno, Aerts, Joachim G J V, van Schaik, Ron H N, Mathijssen, Ron H J, van der Veldt, Astrid A M
Published in Cancers (18.03.2021)
Published in Cancers (18.03.2021)
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Journal Article
Impact of Curcumin (with or without Piperine) on the Pharmacokinetics of Tamoxifen
Hussaarts, Koen G A M, Hurkmans, Daan P, Oomen-de Hoop, Esther, van Harten, Leonie J, Berghuis, Stan, van Alphen, Robbert J, Spierings, Leontine E A, van Rossum-Schornagel, Quirine C, Vastbinder, Mijntje B, van Schaik, Ron H N, van Gelder, Teun, Jager, Agnes, van Leeuwen, Roelof W F, Mathijssen, Ron H J
Published in Cancers (22.03.2019)
Published in Cancers (22.03.2019)
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Journal Article
Prospective real-world study on the pharmacokinetics of pembrolizumab in patients with solid tumors
Hurkmans, Daan P., Sassen, Sebastiaan D.T., de Joode, Karlijn, Putter, Lisanne, Basak, Edwin A., Wijkhuijs, Annemarie J.M., Joerger, Markus, Debets, Reno, Koch, Birgit C.P., Van der Leest, Cor H., Schreurs, Marco W.J., van der Veldt, Astrid A.M., Aerts, Joachim G.J.V., Mathijssen, Ron H.J., Koolen, Stijn L.W.
Published in Journal for immunotherapy of cancer (01.06.2021)
Published in Journal for immunotherapy of cancer (01.06.2021)
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Journal Article
Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer
Hurkmans, Daan P, Verdegaal, Els M E, Hogan, Sabrina A, de Wijn, Rik, Hovestad, Lies, van den Heuvel, Dianne M A, Ruijtenbeek, Rob, Welters, Marij J P, van Brakel, Mandy, Basak, Edwin A, Pinedo, Herbert M, Lamers, Cor H J, van de Werken, Harmen J G, Groten, John P, Debets, Reno, Levesque, Mitchell P, Dummer, Reinhard, Kapiteijn, Ellen, Mathijssen, Ron H J, Aerts, Joachim G J V, van der Burg, Sjoerd H
Published in Journal for immunotherapy of cancer (01.12.2020)
Published in Journal for immunotherapy of cancer (01.12.2020)
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Journal Article
Blood based kinase activity profiling to predict response to immune checkpoint inhibitors in patients with advanced stage non-small cell lung cancer: The IOpener study
de Joode, Karlijn, Groen, Harry J.M., van den Heuvel, Michel M., Kloover, Jeroen S., van der Meer, Femke, van der Leest, Cor H., van den Borne, Ben E.E.M., De Wijn, Rik, Hurkmans, Daan P., van den Heuvel, Dianne M.A., Pinedo, H. M., Kapiteijn, Ellen, Debets, Reno, Verdegaal, Els M.E., van der Burg, S. H., Groten, John P., Aerts, Joachim, Mathijssen, Ron H.J.
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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