The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia
Giotopoulos, G, Chan, W-I, Horton, S J, Ruau, D, Gallipoli, P, Fowler, A, Crawley, C, Papaemmanuil, E, Campbell, P J, Göttgens, B, Van Deursen, J M, Cole, P A, Huntly, B J P
Published in Oncogene (21.01.2016)
Published in Oncogene (21.01.2016)
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Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia
Dawson, M A, Gudgin, E J, Horton, S J, Giotopoulos, G, Meduri, E, Robson, S, Cannizzaro, E, Osaki, H, Wiese, M, Putwain, S, Fong, C Y, Grove, C, Craig, J, Dittmann, A, Lugo, D, Jeffrey, P, Drewes, G, Lee, K, Bullinger, L, Prinjha, R K, Kouzarides, T, Vassiliou, G S, Huntly, B J P
Published in Leukemia (01.02.2014)
Published in Leukemia (01.02.2014)
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Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2
Nangalia, J, Massie, C.E, Baxter, E.J, Nice, F.L, Gundem, G, Wedge, D.C, Avezov, E, Li, J, Kollmann, K, Kent, D.G, Aziz, A, Godfrey, A.L, Hinton, J, Martincorena, I, Van Loo, P, Jones, A.V, Guglielmelli, P, Tarpey, P, Harding, H.P, Fitzpatrick, J.D, Goudie, C.T, Ortmann, C.A, Loughran, S.J, Raine, K, Jones, D.R, Butler, A.P, Teague, J.W, O'Meara, S, McLaren, S, Bianchi, M, Silber, Y, Dimitropoulou, D, Bloxham, D, Mudie, L, Maddison, M, Robinson, B, Keohane, C, Maclean, C, Hill, K, Orchard, K, Tauro, S, Du, M.-Q, Greaves, M, Bowen, D, Huntly, B.J.P, Harrison, C.N, Cross, N.C.P, Ron, D, Vannucchi, A.M, Papaemmanuil, E, Campbell, P.J, Green, A.R
Published in The New England journal of medicine (19.12.2013)
Published in The New England journal of medicine (19.12.2013)
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A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation
Kollmann, K, Warsch, W, Gonzalez-Arias, C, Nice, F L, Avezov, E, Milburn, J, Li, J, Dimitropoulou, D, Biddie, S, Wang, M, Poynton, E, Colzani, M, Tijssen, M R, Anand, S, McDermott, U, Huntly, B, Green, T
Published in Leukemia (01.04.2017)
Published in Leukemia (01.04.2017)
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ESMO-Magnitude of Clinical Benefit Scale for haematological malignancies (ESMO-MCBS:H) version 1.0
Kiesewetter, B., Dafni, U., de Vries, E.G.E., Barriuso, J., Curigliano, G., González-Calle, V., Galotti, M., Gyawali, B., Huntly, B.J.P., Jäger, U., Latino, N.J., Malcovati, L., Oosting, S.F., Ossenkoppele, G., Piccart, M., Raderer, M., Scarfò, L., Trapani, D., Zielinski, C.C., Wester, R., Zygoura, P., Macintyre, E., Cherny, N.I.
Published in Annals of oncology (01.09.2023)
Published in Annals of oncology (01.09.2023)
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A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients
Beck, D, Thoms, J A I, Palu, C, Herold, T, Shah, A, Olivier, J, Boelen, L, Huang, Y, Chacon, D, Brown, A, Babic, M, Hahn, C, Perugini, M, Zhou, X, Huntly, B J, Schwarzer, A, Klusmann, J-H, Berdel, W E, Wörmann, B, Büchner, T, Hiddemann, W, Bohlander, S K, To, L B, Scott, H S, Lewis, I D, D'Andrea, R J, Wong, J W H, Pimanda, J E
Published in Leukemia (01.02.2018)
Published in Leukemia (01.02.2018)
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BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms
Wyspiańska, B S, Bannister, A J, Barbieri, I, Nangalia, J, Godfrey, A, Calero-Nieto, F J, Robson, S, Rioja, I, Li, J, Wiese, M, Cannizzaro, E, Dawson, M A, Huntly, B, Prinjha, R K, Green, A R, Gottgens, B, Kouzarides, T
Published in Leukemia (01.01.2014)
Published in Leukemia (01.01.2014)
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A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients
ORAM, S. H, THOMS, Jai, PIMANDA, J. E, GÖTTGENS, B, PRIDANS, C, JANES, M. E, KINSTON, S. J, ANAND, S, LANDRY, J.-R, LOCK, R. B, JAYARAMAN, P.-S, HUNTLY, B. J
Published in Oncogene (28.10.2010)
Published in Oncogene (28.10.2010)
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Detailed molecular characterisation of acute myeloid leukaemia with a normal karyotype using targeted DNA capture
Conte, N, Varela, I, Grove, C, Manes, N, Yusa, K, Moreno, T, Segonds-Pichon, A, Bench, A, Gudgin, E, Herman, B, Bolli, N, Ellis, P, Haddad, D, Costeas, P, Rad, R, Scott, M, Huntly, B, Bradley, A, Vassiliou, G S
Published in Leukemia (01.09.2013)
Published in Leukemia (01.09.2013)
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Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia
Huntly, Brian J.P., Reid, Alistair G., Bench, Anthony J., Campbell, Lynda J., Telford, Nick, Shepherd, Patricia, Szer, Jeff, Prince, H. Miles, Turner, Paul, Grace, Colin, Nacheva, Elizabeth P., Green, Anthony R.
Published in Blood (15.09.2001)
Published in Blood (15.09.2001)
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HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias
Calero-Nieto, F J, Joshi, A, Bonadies, N, Kinston, S, Chan, W-I, Gudgin, E, Pridans, C, Landry, J-R, Kikuchi, J, Huntly, B J, Gottgens, B
Published in Oncogene (28.11.2013)
Published in Oncogene (28.11.2013)
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Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia
Sinclair, P.B., Nacheva, E.P., Leversha, M., Telford, N., Chang, J., Reid, A., Bench, A., Champion, K., Huntly, B., Green, A.R.
Published in Blood (01.02.2000)
Published in Blood (01.02.2000)
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Visual information processing during controlled hypoglycaemia in humans
McCrimmon, R. J., Deary, I. J., Huntly, B. J. P., MacLeod, K. J., Frier, B. M.
Published in Brain (London, England : 1878) (01.08.1996)
Published in Brain (London, England : 1878) (01.08.1996)
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Mutation of JAK2 in the myeloproliferative disorders: timing, clonality studies, cytogenetic associations, and role in leukemic transformation
Campbell, Peter J., Baxter, E. Joanna, Beer, Philip A., Scott, Linda M., Bench, Anthony J., Huntly, Brian J.P., Erber, Wendy N., Kusec, Rajko, Larsen, Thomas Stauffer, Giraudier, Stéphane, Le Bousse-Kerdilès, Marie-Caroline, Griesshammer, Martin, Reilly, John T., Cheung, Betty Y., Harrison, Claire N., Green, Anthony R.
Published in Blood (15.11.2006)
Published in Blood (15.11.2006)
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Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative chromosome 9 deletions
Huntly, Brian J.P., Guilhot, Francois, Reid, Alistair G., Vassiliou, George, Hennig, Evelin, Franke, Christina, Byrne, Jennie, Brizard, Andre, Niederwieser, Dietger, Freeman-Edward, Julie, Cuthbert, Gavin, Bown, Nick, Clark, Richard E., Nacheva, Elizabeth P, Green, Anthony R, Deininger, Michael W.N.
Published in Blood (15.09.2003)
Published in Blood (15.09.2003)
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The incidences of trisomy 8, trisomy 9 and D20S108 deletion in polycythaemia vera: an analysis of blood granulocytes using interphase fluorescence in situ hybridization
Westwood, N. B., Gruszka‐Westwood, A. M., Pearson, C. E., DeLord, C. F. M., Green, A. R., Huntly, B. J. P., Lakhani, A., McMullin, M. F., Pearson, T. C.
Published in British journal of haematology (01.09.2000)
Published in British journal of haematology (01.09.2000)
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Molecular cytogenetics of polycythaemia vera: lack of occult rearrangements detectable by 20q LSP screening, CGH, and M-FISH
Gribble, S M, Reid, A G, Bench, A J, Huntly, B J P, Grace, C, Green, A R, Nacheva, E P
Published in Leukemia (01.07.2003)
Published in Leukemia (01.07.2003)
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FOXO transcription factor activity is partially retained in quiescent CML stem cells and induced by tyrosine kinase inhibitors in CML progenitor cells
Pellicano, Francesca, Cilloni, Daniela, Helgason, G Vignir, Messa, Francesca, Panuzzo, Cristina, Arruga, Francesca, Bracco, Enrico, Allan, Elaine, Huntly, Brian J P, Holyoake, Tessa L, Saglio, Giuseppe
Published in Blood (01.12.2009)
Published in Blood (01.12.2009)
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Network properties derived from deep sequencing of human B-cell receptor repertoires delineate B-cell populations
Bashford-Rogers, Rachael J M, Palser, Anne L, Huntly, Brian J, Rance, Richard, Vassiliou, George S, Follows, George A, Kellam, Paul
Published in Genome research (01.11.2013)
Published in Genome research (01.11.2013)
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