Design and characterization of an APC-specific serpin for the treatment of hemophilia
Polderdijk, Stéphanie G.I., Adams, Ty E., Ivanciu, Lacramioara, Camire, Rodney M., Baglin, Trevor P., Huntington, James A.
Published in Blood (05.01.2017)
Published in Blood (05.01.2017)
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Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization
Huntington, James A, Yamasaki, Masayuki, Li, Wei, Johnson, Daniel J. D
Published in Nature (30.10.2008)
Published in Nature (30.10.2008)
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Structure and Mechanism of Cysteine Peptidase Gingipain K (Kgp), a Major Virulence Factor of Porphyromonas gingivalis in Periodontitis
de Diego, Iñaki, Veillard, Florian, Sztukowska, Maryta N., Guevara, Tibisay, Potempa, Barbara, Pomowski, Anja, Huntington, James A., Potempa, Jan, Gomis-Rüth, F. Xavier
Published in The Journal of biological chemistry (14.11.2014)
Published in The Journal of biological chemistry (14.11.2014)
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SERPINC1 gene mutations in antithrombin deficiency
Mulder, René, Croles, F. Nanne, Mulder, André B., Huntington, James A., Meijer, Karina, Lukens, Michaël V.
Published in British journal of haematology (01.07.2017)
Published in British journal of haematology (01.07.2017)
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A hereditary bleeding disorder resulting from a premature stop codon in thrombomodulin (p.Cys537Stop)
Langdown, Jonathan, Luddington, Roger J., Huntington, James A., Baglin, Trevor P.
Published in Blood (18.09.2014)
Published in Blood (18.09.2014)
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Ixodes ricinus Salivary Serpin Iripin-8 Inhibits the Intrinsic Pathway of Coagulation and Complement
Kotál, Jan, Polderdijk, Stéphanie G. I., Langhansová, Helena, Ederová, Monika, Martins, Larissa A., Beránková, Zuzana, Chlastáková, Adéla, Hajdušek, Ondřej, Kotsyfakis, Michail, Huntington, James A., Chmelař, Jindřich
Published in International journal of molecular sciences (01.09.2021)
Published in International journal of molecular sciences (01.09.2021)
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Linkage analysis combined with whole-exome sequencing identifies a novel prothrombin ( F2 ) gene mutation in a Dutch Caucasian family with unexplained thrombosis
Mulder, René, Lisman, Ton, Meijers, Joost C M, Huntington, James A, Mulder, André B, Meijer, Karina
Published in Haematologica (Roma) (01.07.2020)
Published in Haematologica (Roma) (01.07.2020)
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NMR resonance assignments of thrombin reveal the conformational and dynamic effects of ligation
Lechtenberg, Bernhard C., Johnson, Daniel J. D., Freund, Stefan M. V., Huntington, James A., Esmon, Charles Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2010)
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Addendum: Kotál et al. Ixodes ricinus Salivary Serpin Iripin-8 Inhibits the Intrinsic Pathway of Coagulation and Complement. Int. J. Mol. Sci. 2021, 22, 9480
Kotál, Jan, Polderdijk, Stéphanie G. I., Langhansová, Helena, Ederová, Monika, Martins, Larissa A., Beránková, Zuzana, Chlastáková, Adéla, Hajdušek, Ondřej, Kotsyfakis, Michail, Huntington, James A., Chmelař, Jindřich
Published in International journal of molecular sciences (19.10.2021)
Published in International journal of molecular sciences (19.10.2021)
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Molecular basis of factor IXa recognition by heparin-activated antithrombin revealed by a 1.7-Å structure of the ternary complex
Johnson, Daniel J.D, Langdown, Jonathan, Huntington, James A
Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2010)
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Homology model of human prothrombinase based on the crystal structure of Pseutarin C
Pomowski, Anja, Ustok, Fatma Isik, Huntington, James A.
Published in Biological chemistry (01.10.2014)
Published in Biological chemistry (01.10.2014)
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Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation
Johnson, Daniel JD, Li, Wei, Adams, Ty E, Huntington, James A
Published in The EMBO journal (03.05.2006)
Published in The EMBO journal (03.05.2006)
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Crystal Structure of Thrombin Bound to Heparin
Carter, Wendy J., Cama, Evis, Huntington, James A.
Published in The Journal of biological chemistry (28.01.2005)
Published in The Journal of biological chemistry (28.01.2005)
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