Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction
England, Elizabeth, Rees, D. Gareth, Scott, Ian Christopher, Carmen, Sara, Chan, Denice T. Y., Chaillan Huntington, Catherine E., Houslay, Kirsty F., Erngren, Teodor, Penney, Mark, Majithiya, Jayesh B., Rapley, Laura, Sims, Dorothy A., Hollins, Claire, Hinchy, Elizabeth C., Strain, Martin D., Kemp, Benjamin P., Corkill, Dominic J., May, Richard D., Vousden, Katherine A., Butler, Robin J., Mustelin, Tomas, Vaughan, Tristan J., Lowe, David C., Colley, Caroline, Cohen, E. Suzanne
Published in Scientific reports (17.06.2023)
Published in Scientific reports (17.06.2023)
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Journal Article
The IL-33:ST2 axis is unlikely to play a central fibrogenic role in idiopathic pulmonary fibrosis
Stephenson, Katherine E, Porte, Joanne, Kelly, Aoife, Wallace, William A, Huntington, Catherine E, Overed-Sayer, Catherine L, Cohen, E Suzanne, Jenkins, R Gisli, John, Alison E
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Published in Respiratory research (23.03.2023)
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Influence of the P5 Residue on α1-Proteinase Inhibitor Mechanism
Chaillan-Huntington, Catherine E., Patston, Philip A.
Published in The Journal of biological chemistry (20.02.1998)
Published in The Journal of biological chemistry (20.02.1998)
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Journal Article
Tozorakimab (MEDI3506): a dual-pharmacology anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction
England, Elizabeth, Rees, D Gareth, Scott, Ian Christopher, Carmen, Sara, Chan, Denice T Y, Chaillan Huntington, Catherine E, Houslay, Kirsty F, Erngren, Teodor, Penney, Mark, Majithiya, Jayesh B, Rapley, Laura, Sims, Dorothy A, Hollins, Claire, Hinchy, Elizabeth C, Strain, Martin D, Kemp, Benjamin P, Corkill, Dominic J, May, Richard D, Vousden, Katherine A, Butler, Robin J, Mustelin, Tomas, Vaughan, Tristan J, Lowe, David C, Colley, Caroline, Cohen, E Suzanne
Published in bioRxiv (01.03.2023)
Published in bioRxiv (01.03.2023)
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Paper
Influence of the P5 Residue on α1-Proteinase Inhibitor Mechanism
Catherine E. Chaillan-Huntington, Philip A. Patston
Published in The Journal of biological chemistry (20.02.1998)
Published in The Journal of biological chemistry (20.02.1998)
Get full text
Journal Article