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Corcoran, Ryan B., Cheng, Katherine A., Hata, Aaron N., Faber, Anthony C., Ebi, Hiromichi, Coffee, Erin M., Greninger, Patricia, Brown, Ronald D., Godfrey, Jason T., Cohoon, Travis J., Song, Youngchul, Lifshits, Eugene, Hung, Kenneth E., Shioda, Toshi, Dias-Santagata, Dora, Singh, Anurag, Settleman, Jeffrey, Benes, Cyril H., Mino-Kenudson, Mari, Wong, Kwok-Kin, Engelman, Jeffrey A.
Published in Cancer cell (14.01.2013)
Published in Cancer cell (14.01.2013)
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Li, Xingnan, Nadauld, Lincoln, Ootani, Akifumi, Corney, David C, Pai, Reetesh K, Gevaert, Olivier, Cantrell, Michael A, Rack, Paul G, Neal, James T, Chan, Carol W-M, Yeung, Trevor, Gong, Xue, Yuan, Jenny, Wilhelmy, Julie, Robine, Sylvie, Attardi, Laura D, Plevritis, Sylvia K, Hung, Kenneth E, Chen, Chang-Zheng, Ji, Hanlee P, Kuo, Calvin J
Published in Nature medicine (01.07.2014)
Published in Nature medicine (01.07.2014)
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Development of a Mouse Model for Sporadic and Metastatic Colon Tumors and Its Use in Assessing Drug Treatment
Hung, Kenneth E., Maricevich, Marco A., Richard, Larissa Georgeon, Chen, Wei Y., Richardson, Michael P., Kunin, Alexandra, Bronson, Roderick T., Mahmood, Umar, Kucherlapati, Raju, Kolodner, Richard D.
Published in Proceedings of the National Academy of Sciences - PNAS (26.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (26.01.2010)
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The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer
Roper, Jatin, Richardson, Michael P, Wang, Wei Vivian, Richard, Larissa Georgeon, Chen, Wei, Coffee, Erin M, Sinnamon, Mark J, Lee, Lydia, Chen, Peng-Chieh, Bronson, Roderick T, Martin, Eric S, Hung, Kenneth E
Published in PloS one (26.09.2011)
Published in PloS one (26.09.2011)
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Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant colorectal cancer
Roper, Jatin, Sinnamon, Mark J, Coffee, Erin M, Belmont, Peter, Keung, Lily, Georgeon-Richard, Larissa, Wang, Wei Vivian, Faber, Anthony C, Yun, Jihye, Yilmaz, Ömer H, Bronson, Roderick T, Martin, Eric S, Tsichlis, Philip N, Hung, Kenneth E
Published in Cancer letters (01.06.2014)
Published in Cancer letters (01.06.2014)
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Cathepsin B Expression and Survival in Colon Cancer: Implications for Molecular Detection of Neoplasia
CHAN, Andrew T, BABA, Yoshifumi, SHUE, Daniel, KUCHERLAPATI, Raju, FUCHS, Charles S, OGINO, Shuji, SHIMA, Kaori, NOSHO, Katsuhiko, CHUNG, Daniel C, HUNG, Kenneth E, MAHMOOD, Umar, MADDEN, Karen, POSS, Kirtland, RANIERI, Audrey
Published in Cancer epidemiology, biomarkers & prevention (01.11.2010)
Published in Cancer epidemiology, biomarkers & prevention (01.11.2010)
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PKM2 is not required for colon cancer initiated by APC loss
Lau, Allison N, Israelsen, William J, Roper, Jatin, Sinnamon, Mark J, Georgeon, Larissa, Dayton, Talya L, Hillis, Alissandra L, Yilmaz, Omer H, Di Vizio, Dolores, Hung, Kenneth E, Vander Heiden, Matthew G
Published in Cancer & metabolism (30.11.2017)
Published in Cancer & metabolism (30.11.2017)
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Adenoma―linked barrier defects and microbial products drive IL―23/IL―17―mediated tumour growth
GRIVENNIKOV, Sergei I, KEPENG WANG, DATZ, Christian, YING FENG, FEARON, Eric R, OUKKA, Mohamed, TESSAROLLO, Lino, COPPOLA, Vincenzo, YAROVINSKY, Felix, CHEROUTRE, Hilde, ECKMANN, Lars, TRINCHIERI, Giorgio, MUCIDA, Daniel, KARIN, Michael, STEWART, C. Andrew, SCHNABL, Bernd, JAUCH, Dominik, TANIGUCHI, Koji, YU, Guann-Yi, ÖSTERREICHER, Christoph H, HUNG, Kenneth E
Published in Nature (London) (08.11.2012)
Published in Nature (London) (08.11.2012)
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Oral Ritlecitinib and Brepocitinib for Moderate-to-Severe Ulcerative Colitis: Results From a Randomized, Phase 2b Study
Sandborn, William J., Danese, Silvio, Leszczyszyn, Jaroslaw, Romatowski, Jacek, Altintas, Engin, Peeva, Elena, Hassan-Zahraee, Mina, Vincent, Michael S., Reddy, Padmalatha S., Banfield, Christopher, Salganik, Mikhail, Banerjee, Anindita, Gale, Jeremy D., Hung, Kenneth E.
Published in Clinical gastroenterology and hepatology (01.09.2023)
Published in Clinical gastroenterology and hepatology (01.09.2023)
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In Vivo Optical Molecular Imaging of Matrix Metalloproteinase Activity following Celecoxib Therapy for Colorectal Cancer
Sheth, Rahul A., Kunin, Alexandra, Stangenberg, Lars, Sinnamon, Mark, Hung, Kenneth E., Kucherlapati, Raju, Mahmood, Umar
Published in Molecular imaging (01.09.2012)
Published in Molecular imaging (01.09.2012)
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Anti-TL1A Antibody PF-06480605 Safety and Efficacy for Ulcerative Colitis: A Phase 2a Single-Arm Study
Danese, Silvio, Klopocka, Maria, Scherl, Ellen J., Romatowski, Jacek, Allegretti, Jessica R., Peeva, Elena, Vincent, Michael S., Schoenbeck, Uwe, Ye, Zhan, Hassan-Zahraee, Mina, Rath, Natalie, Li, Gang, Neelakantan, Srividya, Banfield, Christopher, Lepsy, Christopher, Chandra, Deepa E., Hung, Kenneth E.
Published in Clinical gastroenterology and hepatology (01.11.2021)
Published in Clinical gastroenterology and hepatology (01.11.2021)
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Concomitant BRAF and PI3K/mTOR Blockade Is Required for Effective Treatment of BRAFV600E Colorectal Cancer
COFFEE, Erin M, FABER, Anthony C, BRONSON, Roderick T, TEJPAR, Sabine, XAVIER, Ramnik J, ENGELMAN, Jeffrey A, MARTIN, Eric S, HUNG, Kenneth E, ROPER, Jatin, SINNAMON, Mark J, GOEL, Gautam, KEUNG, Lily, WEI VIVIAN WANG, VECCHIONE, Loredana, DE VRIENDT, Veerle, WEINSTEIN, Barbara J
Published in Clinical cancer research (15.05.2013)
Published in Clinical cancer research (15.05.2013)
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Priceless GEMMs: genetically engineered mouse models for colorectal cancer drug development
Roper, Jatin, Hung, Kenneth E
Published in Trends in pharmacological sciences (Regular ed.) (01.08.2012)
Published in Trends in pharmacological sciences (Regular ed.) (01.08.2012)
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Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease
Belmont, Peter J, Budinska, Eva, Jiang, Ping, Sinnamon, Mark J, Coffee, Erin, Roper, Jatin, Xie, Tao, Rejto, Paul A, Derkits, Sahra, Sansom, Owen J, Delorenzi, Mauro, Tejpar, Sabine, Hung, Kenneth E, Martin, Eric S
Published in Disease models & mechanisms (01.06.2014)
Published in Disease models & mechanisms (01.06.2014)
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Antitumor Necrosis Factor-like Ligand 1A Therapy Targets Tissue Inflammation and Fibrosis Pathways and Reduces Gut Pathobionts in Ulcerative Colitis
Hassan-Zahraee, Mina, Ye, Zhan, Xi, Li, Baniecki, Mary Lynn, Li, Xingpeng, Hyde, Craig L, Zhang, Jenny, Raha, Nancy, Karlsson, Fridrik, Quan, Jie, Ziemek, Daniel, Neelakantan, Srividya, Lepsy, Christopher, Allegretti, Jessica R, Romatowski, Jacek, Scherl, Ellen J, Klopocka, Maria, Danese, Silvio, Chandra, Deepa E, Schoenbeck, Uwe, Vincent, Michael S, Longman, Randy, Hung, Kenneth E
Published in Inflammatory bowel diseases (02.03.2022)
Published in Inflammatory bowel diseases (02.03.2022)
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First‐in‐human, randomized dose‐escalation study of the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of PF‐06480605 in healthy subjects
Banfield, Christopher, Rudin, Dan, Bhattacharya, Indranil, Goteti, Kosalaram, Li, Gang, Hassan‐Zahraee, Mina, Brown, Lisa S., Hung, Kenneth E., Pawlak, Sylvester, Lepsy, Christopher
Published in British journal of clinical pharmacology (01.04.2020)
Published in British journal of clinical pharmacology (01.04.2020)
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In vivo wide-area cellular imaging by side-view endomicroscopy
Yun, Seok H, Kim, Pilhan, Chung, Euiheon, Yamashita, Hiroshi, Hung, Kenneth E, Mizoguchi, Atsushi, Kucherlapati, Raju, Fukumura, Dai, Jain, Rakesh K
Published in Nature methods (01.04.2010)
Published in Nature methods (01.04.2010)
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Baseline serum and stool microbiome biomarkers predict clinical efficacy and tissue molecular response after ritlecitinib induction therapy in ulcerative colitis
Hassan-Zahraee, Mina, Ye, Zhan, Xi, Li, Dushin, Elizabeth, Lee, Julie, Romatowski, Jacek, Leszczyszyn, Jaroslaw, Danese, Silvio, Sandborn, William J, Banfield, Christopher, Gale, Jeremy D, Peeva, Elena, Longman, Randy S, Hyde, Craig L, Hung, Kenneth E
Published in Journal of Crohn's and colitis (03.09.2024)
Published in Journal of Crohn's and colitis (03.09.2024)
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A HUPO test sample study reveals common problems in mass spectrometry-based proteomics
Bergeron, John J M, Bell, Alexander W, Deutsch, Eric W, Au, Catherine E, Kearney, Robert E, Beavis, Ron, Sechi, Salvatore, Nilsson, Tommy
Published in Nature methods (01.06.2009)
Published in Nature methods (01.06.2009)
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Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer
Coffee, Erin M, Faber, Anthony C, Roper, Jatin, Sinnamon, Mark J, Goel, Gautam, Keung, Lily, Wang, Wei Vivian, Vecchione, Loredana, de Vriendt, Veerle, Weinstein, Barbara J, Bronson, Roderick T, Tejpar, Sabine, Xavier, Ramnik J, Engelman, Jeffrey A, Martin, Eric S, Hung, Kenneth E
Published in Clinical cancer research (15.05.2013)
Published in Clinical cancer research (15.05.2013)
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