Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling
Niewiadomski, Pawel, Kong, Jennifer H, Ahrends, Robert, Ma, Yan, Humke, Eric W, Khan, Sohini, Teruel, Mary N, Novitch, Bennett G, Rohatgi, Rajat
Published in Cell reports (Cambridge) (01.01.2014)
Published in Cell reports (Cambridge) (01.01.2014)
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Journal Article
Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer
Barakat, Monique T, Humke, Eric W, Scott, Matthew P
Published in Trends in molecular medicine (01.08.2010)
Published in Trends in molecular medicine (01.08.2010)
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NOD2-NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide
Hsu, Li-Chung, Ali, Syed R, McGillivray, Shauna, Tseng, Ping-Hui, Mariathasan, Sanjeev, Humke, Eric W, Eckmann, Lars, Powell, Jonathan J, Nizet, Victor, Dixit, Vishva M, Karin, Michael
Published in Proceedings of the National Academy of Sciences - PNAS (03.06.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (03.06.2008)
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Journal Article
Multimeric Anti-DR5 IgM Agonist Antibody IGM-8444 Is a Potent Inducer of Cancer Cell Apoptosis and Synergizes with Chemotherapy and BCL-2 Inhibitor ABT-199
Wang, Beatrice T, Kothambawala, Tasnim, Wang, Ling, Matthew, Thomas J, Calhoun, Susan E, Saini, Avneesh K, Kotturi, Maya F, Hernandez, Genevive, Humke, Eric W, Peterson, Marvin S, Sinclair, Angus M, Keyt, Bruce A
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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An Open-label Phase I Study of GDC-0927 in Postmenopausal Women with Locally Advanced or Metastatic Estrogen Receptor-Positive Breast Cancer
Chandarlapaty, Sarat, Dickler, Maura N, Perez Fidalgo, Jose Alejandro, Villanueva-Vázquez, Rafael, Giltnane, Jennifer, Gates, Mary, Chang, Ching-Wei, Cheeti, Sravanthi, Fredrickson, Jill, Wang, Xiaojing, Collier, Ann, Moore, Heather M, Metcalfe, Ciara, Lauchle, Jennifer, Humke, Eric W, Bardia, Aditya
Published in Clinical cancer research (01.08.2023)
Published in Clinical cancer research (01.08.2023)
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Kif3a is necessary for initiation and maintenance of medulloblastoma
Barakat, Monique T, Humke, Eric W, Scott, Matthew P
Published in Carcinogenesis (New York) (01.06.2013)
Published in Carcinogenesis (New York) (01.06.2013)
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Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips
Earhart, Christopher M, Hughes, Casey E, Gaster, Richard S, Ooi, Chin Chun, Wilson, Robert J, Zhou, Lisa Y, Humke, Eric W, Xu, Lingyun, Wong, Dawson J, Willingham, Stephen B, Schwartz, Erich J, Weissman, Irving L, Jeffrey, Stefanie S, Neal, Joel W, Rohatgi, Rajat, Wakelee, Heather A, Wang, Shan X
Published in Lab on a chip (07.01.2014)
Published in Lab on a chip (07.01.2014)
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Phase Ia Study of Anti-NaPi2b Antibody-Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Patients with Non-Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer
Gerber, David E, Infante, Jeffrey R, Gordon, Michael S, Goldberg, Sarah B, Martín, Miguel, Felip, Enriqueta, Martinez Garcia, Maria, Schiller, Joan H, Spigel, David R, Cordova, Julie, Westcott, Valerie, Wang, Yulei, Shames, David S, Choi, YounJeong, Kahn, Robert, Dere, Randall C, Samineni, Divya, Xu, Jian, Lin, Kedan, Wood, Katie, Royer-Joo, Stephanie, Lemahieu, Vanessa, Schuth, Eva, Vaze, Anjali, Maslyar, Daniel, Humke, Eric W, Burris, 3rd, Howard A
Published in Clinical cancer research (15.01.2020)
Published in Clinical cancer research (15.01.2020)
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Phase 1b study of anti-NaPi2b antibody-drug conjugate lifastuzumab vedotin (DNIB0600A) in patients with platinum-sensitive recurrent ovarian cancer
Moore, Kathleen N., Birrer, Michael J., Marsters, Jim, Wang, Yulei, Choi, YounJeong, Royer-Joo, Stephanie, Lemahieu, Vanessa, Armstrong, Katy, Cordova, Julie, Samineni, Divya, Schuth, Eva, Vaze, Anjali, Maslyar, Daniel, Humke, Eric W., Hamilton, Erika P., Liu, Joyce F.
Published in Gynecologic oncology (01.09.2020)
Published in Gynecologic oncology (01.09.2020)
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Phase I study of the anti-FcRH5 antibody-drug conjugate DFRF4539A in relapsed or refractory multiple myeloma
Stewart, A. Keith, Krishnan, Amrita Y., Singhal, Seema, Boccia, Ralph V., Patel, Manish R., Niesvizky, Ruben, Chanan-Khan, Asher A., Ailawadhi, Sikander, Brumm, Jochen, Mundt, Kirsten E., Hong, Kyu, McBride, Jacqueline, Shon-Nguyen, Quyen, Xiao, Yuanyuan, Ramakrishnan, Vanitha, Polson, Andrew G., Samineni, Divya, Leipold, Douglas, Humke, Eric W., McClellan, James Scott, Berdeja, Jesus G.
Published in Blood cancer journal (New York) (04.02.2019)
Published in Blood cancer journal (New York) (04.02.2019)
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Journal Article
ICEBERG: A Novel Inhibitor of Interleukin-1β Generation
Humke, Eric W, Shriver, Stephanie K, Starovasnik, Melissa A, Fairbrother, Wayne J, Dixit, Vishva M
Published in Cell (29.09.2000)
Published in Cell (29.09.2000)
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Journal Article
Caspase-9 Can Be Activated without Proteolytic Processing
Stennicke, H R, Deveraux, Q L, Humke, E W, Reed, J C, Dixit, V M, Salvesen, G S
Published in The Journal of biological chemistry (26.03.1999)
Published in The Journal of biological chemistry (26.03.1999)
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Journal Article
The PYRIN domain: A member of the death domain‐fold superfamily
Fairbrother, Wayne J., Gordon, Nathaniel C., Humke, Eric W., O'Rourke, Karen M., Starovasnik, Melissa A., Yin, Jian‐Ping, Dixit, Vishva M.
Published in Protein science (01.09.2001)
Published in Protein science (01.09.2001)
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An open-label phase I dose-escalation study of the safety and pharmacokinetics of DMUC4064A in patients with platinum-resistant ovarian cancer
Liu, Joyce, Burris, Howard, Wang, Judy S., Barroilhet, Lisa, Gutierrez, Martin, Wang, Yulei, Vaze, Anjali, Commerford, Renee, Royer-Joo, Stephanie, Choeurng, Voleak, Humke, Eric, Moore, Kathleen
Published in Gynecologic oncology (01.12.2021)
Published in Gynecologic oncology (01.12.2021)
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Abstract P5-11-07: Real-world predictors of first-line treatment and descriptive outcomes in HR+/HER2− metastatic breast cancer patients in the US
Downer, MK, Jhaveri, Komal, Bardia, Aditya, Loi, Sherene, Kent, Matthew, Luhn, Patricia, Humke, Eric W.
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Journal Article
The Anti-Tumor Activity of Igm-8444, an Agonistic Death Receptor 5 (DR5) IgM Antibody, Is Sensitized in Combination with Chemotherapy and Bcl-2 Inhibitors in NHL and AML
Wang, Beatrice T., Matthew, Thomas J., Wang, Ling, Kothambawala, Tasnim, Calhoun, Susan E., Humke, Eric W., Sinclair, Angus M., Keyt, Bruce A.
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
IGM-8444 as a potent agonistic Death Receptor 5 (DR5) IgM antibody: Induction of tumor cytotoxicity, combination with chemotherapy and in vitro safety profile
Wang, Beatrice, Wang, Ling, Kothambawala, Tasnim, Calhoun, Susan, Matthew, Thomas, Hernandez, Genevive, Peterson, Marvin, Sinclair, Angus, Humke, Eric William, Keyt, Bruce
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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