Resolution of etodolac and antiinflammatory and prostaglandin synthetase inhibiting properties of the enantiomers
Demerson, Christopher A, Humber, Leslie G, Abraham, Nedumparambil A, Schilling, Gunther, Martel, Rene R, Pace-Asciak, Cecil
Published in Journal of medicinal chemistry (01.12.1983)
Published in Journal of medicinal chemistry (01.12.1983)
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Journal Article
Synthesis of derivatives of isoindole and of pyrazino[2,1-a]isoindole
Ferland, Jean-Marie, Demerson, Christopher A, Humber, Leslie G
Published in Canadian journal of chemistry (01.02.1985)
Published in Canadian journal of chemistry (01.02.1985)
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Journal Article
Resolved 6,7,8,9-tetrahydro-N,N-dimethyl-3H-benz[e]indol-8-amine: central dopamine and serotonin receptor stimulating properties
Wikstroem, Haakan, Andersson, Bengt, Svensson, Arne, Humber, Leslie G, Asselin, Andre A, Svensson, Kjell, Ekman, Agneta, Carlsson, Arvid, Nilsson, Ingemar, Chidester, Connie
Published in Journal of medicinal chemistry (01.10.1989)
Published in Journal of medicinal chemistry (01.10.1989)
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Journal Article
Syntheses of 4,12-Dimethyl[2.2]metacyclophane
Lindsay, W. S, Stokes, Peter, Humber, Leslie G, Boekelheide, V
Published in Journal of the American Chemical Society (01.02.1961)
Published in Journal of the American Chemical Society (01.02.1961)
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Journal Article
Drug design via pharmacophore identification. Dopaminergic activity of 3H-benz[e]indol-8-amines and their mode of interaction with the dopamine receptor
Asselin, Andre A, Humber, Leslie G, Voith, Katherine, Metcalf, Geoffrey
Published in Journal of medicinal chemistry (01.05.1986)
Published in Journal of medicinal chemistry (01.05.1986)
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Journal Article
The synthesis and structural characterization of way-120,491; a novel potassium channel activator
Quagliato, Dominick A., Humber, Leslie G., Joslyn, Betsy L., Soll, Richard M., Browne, Eric N.C., Shaw, Chiacheng, Van Engen, Donna
Published in Bioorganic & medicinal chemistry letters (1991)
Published in Bioorganic & medicinal chemistry letters (1991)
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Journal Article
Etodolac, a novel antiinflammatory agent. The syntheses and biological evaluation of its metabolites
Humber, Leslie G, Ferdinandi, Eckhardt, Demerson, Christopher A, Ahmed, Syed, Shah, Uresh, Mobilio, Dominick, Sabatucci, Joseph, De Lange, Barbara, Labbadia, Francesco
Published in Journal of medicinal chemistry (01.09.1988)
Published in Journal of medicinal chemistry (01.09.1988)
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Journal Article
Etodolac, a novel antiinflammatory agent. The syntheses and biological evaluation of its metabolites [Erratum to document cited in CA109(11):92846a]
Humber, Leslie G, Ferdinandi, Eckhardt, Demerson, Christopher A, Ahmed, Syed, Shah, Uresh, Mobilio, Dominick, Sabatucci, Joseph, De Lange, Barbara, Labbadia, Francesco
Published in Journal of medicinal chemistry (01.12.1989)
Published in Journal of medicinal chemistry (01.12.1989)
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Journal Article
1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid: a potent antiinflammatory drug. Conformation and absolute configuration of its active enantiomer
Humber, Leslie G, Demerson, Christopher A, Swaminathan, Panchanadam
Published in Journal of medicinal chemistry (01.05.1986)
Published in Journal of medicinal chemistry (01.05.1986)
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Journal Article
Synthesis and biological evaluation of 4,6-diethyl-1,3,4,5-tetrahydropyrano[4,3-b]indole-4-acetic acid, an isomer of etodolac
Hughes, Philip, DeVirgilio, John, Humber, Leslie G, Chau Thuy, Weichman, Barry, Neuman, Glen
Published in Journal of medicinal chemistry (01.09.1989)
Published in Journal of medicinal chemistry (01.09.1989)
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Journal Article
Structure-activity relationships among analogues of pemedolac, cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]indole-1-acetic acid, a potent analgesic agent
Mobilio, Dominick, Humber, Leslie G, Katz, Alan H, Demerson, Christopher A, Hughes, Philip, Brigance, Robert, Conway, Kimberly, Shah, Uresh, Williams, Gail
Published in Journal of medicinal chemistry (01.11.1988)
Published in Journal of medicinal chemistry (01.11.1988)
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Journal Article
Indole-phenol-bioisosterism. Synthesis and antihypertensive activity of a pyrrolo analog of labetalol
Asselin, Andre A, Humber, Leslie G, Crosilla, Danilo, Oshiro, George, Wojdan, Alexandra, Grimes, David, Heaslip, Richard J, Rimele, Thomas J, Shaw, Chia Cheng
Published in Journal of medicinal chemistry (01.06.1986)
Published in Journal of medicinal chemistry (01.06.1986)
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