Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V₁b receptor antagonists
Napier, Susan E, Letourneau, Jeffrey J, Ansari, Nasrin, Auld, Douglas S, Baker, James, Best, Stuart, Campbell-Wan, Leigh, Chan, Jui-Hsiang, Craighead, Mark, Desai, Hema, Goan, Katharine A, Ho, Koc-Kan, Hulskotte, Ellen G.J, MacSweeney, Cliona P, Milne, Rachel, Morphy, J. Richard, Neagu, Irina, Ohlmeyer, Michael H.J, Peeters, Ard W.M.M, Presland, Jeremy, Riviello, Chris, Ruigt, Ge S.F, Thomson, Fiona J, Zanetakos, Heather A, Zhao, Jiuqiao, Webb, Maria L
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Pharmacokinetics and Tolerability of Letermovir Coadministered With Azole Antifungals (Posaconazole or Voriconazole) in Healthy Subjects
Marshall, William L, McCrea, Jacqueline B, Macha, Sreeraj, Menzel, Karsten, Liu, Fang, van Schanke, Arne, de Haes, Joanna I Udo, Hussaini, Azra, Jordan, Heather R, Drexel, Melissa, Kantesaria, Bhavna S, Tsai, Christine, Cho, Carolyn R, Hulskotte, Ellen G J, Butterton, Joan R, Iwamoto, Marian
Published in Journal of clinical pharmacology (01.07.2018)
Published in Journal of clinical pharmacology (01.07.2018)
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Pharmacokinetics and safety of letermovir, a novel anti‐human cytomegalovirus drug, in patients with renal impairment
Kropeit, Dirk, Scheuenpflug, Jürgen, Erb‐Zohar, Katharina, Halabi, Atef, Stobernack, Hans‐Peter, Hulskotte, Ellen G. J., Schanke, Arne, Zimmermann, Holger, Rübsamen‐Schaeff, Helga
Published in British journal of clinical pharmacology (01.09.2017)
Published in British journal of clinical pharmacology (01.09.2017)
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Pharmacokinetic Interactions Between the Hepatitis C Virus Protease Inhibitor Boceprevir and Ritonavir-Boosted HIV-1 Protease Inhibitors Atazanavir, Darunavir, and Lopinavir
Hulskotte, Ellen G. J., Feng, Hwa-Ping, Xuan, Fengjuan, van Zutven, Marga G. J. A., Treitel, Michelle A., Hughes, Eric A., O'Mara, Edward, Youngberg, Stephen P., Wagner, John A., Butterton, Joan R.
Published in Clinical infectious diseases (01.03.2013)
Published in Clinical infectious diseases (01.03.2013)
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Clinical Pharmacology Profile of Boceprevir, a Hepatitis C Virus NS3 Protease Inhibitor: Focus on Drug–Drug Interactions
Khalilieh, Sauzanne, Feng, Hwa-Ping, Hulskotte, Ellen G. J., Wenning, Larissa A., Butterton, Joan R.
Published in Clinical pharmacokinetics (01.06.2015)
Published in Clinical pharmacokinetics (01.06.2015)
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Pharmacokinetic interaction between HCV protease inhibitor boceprevir and methadone or buprenorphine in subjects on stable maintenance therapy
Hulskotte, Ellen G. J., Bruce, R. Douglas, Feng, Hwa-Ping, Webster, Lynn R., Xuan, Feng, Lin, Wen H., O’Mara, Edward, Wagner, John A., Butterton, Joan R.
Published in European journal of clinical pharmacology (01.03.2015)
Published in European journal of clinical pharmacology (01.03.2015)
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Journal Article
Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4 H)-yl)acetamide vasopressin V 1b receptor antagonists
Napier, Susan E., Letourneau, Jeffrey J., Ansari, Nasrin, Auld, Douglas S., Baker, James, Best, Stuart, Campbell-Wan, Leigh, Chan, Jui-Hsiang, Craighead, Mark, Desai, Hema, Goan, Katharine A., Ho, Koc-Kan, Hulskotte, Ellen G.J., MacSweeney, Cliona P., Milne, Rachel, Morphy, J. Richard, Neagu, Irina, Ohlmeyer, Michael H.J., Peeters, Ard W.M.M., Presland, Jeremy, Riviello, Chris, Ruigt, Ge S.F., Thomson, Fiona J., Zanetakos, Heather A., Zhao, Jiuqiao, Webb, Maria L.
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Journal Article
Towards and HIV-1 vaccine: lessons from studies in macaque models
Hulskotte, Ellen G.J., Geretti, Anna-Maria, Osterhaus, Albert D.M.E.
Published in Vaccine (01.05.1998)
Published in Vaccine (01.05.1998)
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Vaccine-induced virus-neutralizing antibodies and cytotoxic T cells do not protect macaques from experimental infection with simian immunodeficiency virus SIVmac32H (J5)
Hulskotte, E G, Geretti, A M, Siebelink, K H, van Amerongen, G, Cranage, M P, Rud, E W, Norley, S G, de Vries, P, Osterhaus, A D
Published in Journal of Virology (01.10.1995)
Published in Journal of Virology (01.10.1995)
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Decline of Simian Immunodeficiency Virus (SIV)-Specific Cytotoxic T Lymphocytes in the Peripheral Blood of Long-Term Nonprogressing Macaques Infected with SIVmac32H-J5
Geretti, Anna-Maria, Hulskotte, Ellen G. J., Dings, Marlinda E. M., van Baalen, Carel A., van Amerongen, Geert, Norley, Stephen G., Boers, Patrick, Graters, Rob, Osterhaus, Albert D. M. E.
Published in The Journal of infectious diseases (01.10.1999)
Published in The Journal of infectious diseases (01.10.1999)
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Journal Article
Chemical inactivation of recombinant vaccinia viruses and the effects on antigenicity and immunogenicity of recombinant simian immunodeficiency virus envelope glycoproteins
Hulskotte, Ellen G.J., Dings, Marlinda E.M., Norley, Stephen G., Osterhaus, Albert D.M.E.
Published in Vaccine (01.12.1997)
Published in Vaccine (01.12.1997)
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Journal Article
CD8+ cytotoxic T lymphocytes of a cynomolgus macaque infected with simian immunodeficiency virus (SIV) mac32H-J5 recognize a nine amino acid epitope in SIV Gag p26
Geretti, AM, Hulskotte, EG, Dings, ME, van Baalen, CA, van Amerongen, G, Osterhaus, AD
Published in Journal of general virology (01.04.1997)
Published in Journal of general virology (01.04.1997)
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Simian immunodeficiency virus (SIV)-specific CD8 + cytotoxic T lymphocyte responses of naive and vaccinated cynomolgus macaques infected with SIVmac32H(J5): quantitative analysis by in vitro antigenic stimulation
Geretti, Anna-Maria, Hulskotte, Ellen G.J., Dings, Marlinda E.M., van Baalen, Carel A., van Amerongen, Geert, Osterhaus, Albert D.M.E.
Published in Vaccine (01.08.1997)
Published in Vaccine (01.08.1997)
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Journal Article
Protection of rhesus macaques from SIV infection by immunization with different experimental SIV vaccines
de Vries, Petra, Heeney, Jonathan L., Boes, Jolande, Dings, Marlinda E.M., Hulskotte, Ellen G.J., Dubbes, Rob, Koornstra, Willem, ten Haaft, Peter, Åkerblom, Lennart, Eriksson, Sigrid, Morein, Bror, Norley, Steve, Osterhaus, Albert D.M.E.
Published in Vaccine (1994)
Published in Vaccine (1994)
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Antigenicity and immunogenicity of recombinant envelope glycoproteins of SIVmac32H with different in vivo passage histories
Hulskotte, Ellen G.J., Rimmelzwaan, Guus F., Boes, Jolande, Bosch, Marnix L., Heeney, Jonathan L., Norley, Stephen G., de Vries, Petra, Osterhaus, Albert D.M.E.
Published in Vaccine (1995)
Published in Vaccine (1995)
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