Functional characterization of the selective pan-allele anti-SIRPα antibody ADU-1805 that blocks the SIRPα–CD47 innate immune checkpoint
Voets, Erik, Paradé, Marc, Lutje Hulsik, David, Spijkers, Sanne, Janssen, Wout, Rens, Joost, Reinieren-Beeren, Inge, van den Tillaart, Gilbert, van Duijnhoven, Sander, Driessen, Lilian, Habraken, Maurice, van Zandvoort, Peter, Kreijtz, Joost, Vink, Paul, van Elsas, Andrea, van Eenennaam, Hans
Published in Journal for immunotherapy of cancer (04.12.2019)
Published in Journal for immunotherapy of cancer (04.12.2019)
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Journal Article
Epitope mapping of monoclonal antibodies: a comprehensive comparison of different technologies
Dang, Xibei, Guelen, Lars, Lutje Hulsik, David, Ermakov, Grigori, Hsieh, Edward J, Kreijtz, Joost, Stammen-Vogelzangs, Judith, Lodewijks, Imke, Bertens, Astrid, Bramer, Arne, Guadagnoli, Marco, Nazabal, Alexis, van Elsas, Andrea, Fischmann, Thierry, Juan, Veronica, Beebe, Amy, Beaumont, Maribel, van Eenennaam, Hans
Published in mAbs (2023)
Published in mAbs (2023)
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Journal Article
Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions
Lameris, Roeland, Shahine, Adam, Veth, Myrthe, Westerman, Bart, Godfrey, Dale I, Lutje Hulsik, David, Brouwer, Patricia, Rossjohn, Jamie, de Gruijl, Tanja D, van der Vliet, Hans J
Published in Journal for immunotherapy of cancer (01.12.2023)
Published in Journal for immunotherapy of cancer (01.12.2023)
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Journal Article
Structural Basis for ESCRT-III CHMP3 Recruitment of AMSH
Solomons, Julianna, Sabin, Charles, Poudevigne, Emilie, Usami, Yoshiko, Hulsik, David Lutje, Macheboeuf, Pauline, Hartlieb, Bettina, Göttlinger, Heinrich, Weissenhorn, Winfried
Published in Structure (London) (10.08.2011)
Published in Structure (London) (10.08.2011)
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Journal Article
Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41
Sabin, Charles, Corti, Davide, Buzon, Victor, Seaman, Mike S, Lutje Hulsik, David, Hinz, Andreas, Vanzetta, Fabrizia, Agatic, Gloria, Silacci, Chiara, Mainetti, Lara, Scarlatti, Gabriella, Sallusto, Federica, Weiss, Robin, Lanzavecchia, Antonio, Weissenhorn, Winfried
Published in PLoS pathogens (01.11.2010)
Published in PLoS pathogens (01.11.2010)
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Journal Article
Isolation of Llama Antibody Fragments for Prevention of Dandruff by Phage Display in Shampoo
Dolk, Edward, van der Vaart, Marcel, Lutje Hulsik, David, Vriend, Gert, de Haard, Hans, Spinelli, Silvia, Cambillau, Christian, Frenken, Leon, Verrips, Theo
Published in Applied and Environmental Microbiology (2005)
Published in Applied and Environmental Microbiology (2005)
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Journal Article
Crystal Structure of the Neutralizing Llama VHH D7 and Its Mode of HIV-1 gp120 Interaction
Hinz, Andreas, Lutje Hulsik, David, Forsman, Anna, Koh, Willie Wee-Lee, Belrhali, Hassan, Gorlani, Andrea, de Haard, Hans, Weiss, Robin A., Verrips, Theo, Weissenhorn, Winfried
Published in PloS one (05.05.2010)
Published in PloS one (05.05.2010)
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Journal Article
Calpain 3 is a rapid-action, unidirectional proteolytic switch central to muscle remodeling
de Morrée, Antoine, Lutje Hulsik, David, Impagliazzo, Antonietta, van Haagen, Herman H H B M, de Galan, Paula, van Remoortere, Alexandra, 't Hoen, Peter A C, van Ommen, Gertjan B, Frants, Rune R, van der Maarel, Silvère M
Published in PloS one (04.08.2010)
Published in PloS one (04.08.2010)
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Journal Article
Vδ2 T-cell engagers bivalent for Vδ2-TCR binding provide anti-tumor immunity and support robust Vγ9Vδ2 T-cell expansion
King, Lisa A., de Jong, Milon, Veth, Myrthe, Lutje Hulsik, David, Yousefi, Parsa, Iglesias-Guimarais, Victoria, van Helden, Pauline M., de Gruijl, Tanja D., van der Vliet, Hans J.
Published in Frontiers in oncology (18.10.2024)
Published in Frontiers in oncology (18.10.2024)
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Journal Article
Llama antibody fragments recognizing various epitopes of the CD4bs neutralize a broad range of HIV-1 subtypes A, B and C
Strokappe, Nika, Szynol, Agnieszka, Aasa-Chapman, Marlèn, Gorlani, Andrea, Forsman Quigley, Anna, Hulsik, David Lutje, Chen, Lei, Weiss, Robin, de Haard, Hans, Verrips, Theo
Published in PloS one (15.03.2012)
Published in PloS one (15.03.2012)
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Journal Article
A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition
Lutje Hulsik, David, Liu, Ying-ying, Strokappe, Nika M, Battella, Simone, El Khattabi, Mohamed, McCoy, Laura E, Sabin, Charles, Hinz, Andreas, Hock, Miriam, Macheboeuf, Pauline, Bonvin, Alexandre M J J, Langedijk, Johannes P M, Davis, David, Forsman Quigley, Anna, Aasa-Chapman, Marlén M I, Seaman, Michael S, Ramos, Alejandra, Poignard, Pascal, Favier, Adrien, Simorre, Jean-Pierre, Weiss, Robin A, Verrips, C Theo, Weissenhorn, Winfried, Rutten, Lucy
Published in PLoS pathogens (01.03.2013)
Published in PLoS pathogens (01.03.2013)
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Journal Article
Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy
Guelen, Lars, Fischmann, Thierry O, Wong, Jerelyn, Mauze, Smita, Guadagnoli, Marco, Bąbała, Nikolina, Wagenaars, Jozef, Juan, Veronica, Rosen, David, Prosise, Winnie, Habraken, Maurice, Lodewijks, Imke, Gu, Danling, Stammen-Vogelzangs, Judith, Yu, Ying, Baker, Jeanne, Lutje Hulsik, David, Driessen-Engels, Lilian, Malashock, Dan, Kreijtz, Joost, Bertens, Astrid, de Vries, Evert, Bovens, Astrid, Bramer, Arne, Zhang, Yiwei, Wnek, Richard, Troth, Sean, Chartash, Elliot, Dobrenkov, Konstantin, Sadekova, Svetlana, van Elsas, Andrea, Cheung, Jason K, Fayadat-Dilman, Laurence, Borst, Jannie, Beebe, Amy M, Van Eenennaam, Hans
Published in Journal for immunotherapy of cancer (01.09.2022)
Published in Journal for immunotherapy of cancer (01.09.2022)
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Journal Article
SIRP ANTI-SIRP ALPHA ANTIBODIES
VAN EENENNAAM HANS, HULSIK DAVID LUTJE, VAN ELSAS ANDREA, VINK PAUL, VOETS ERIK
Year of Publication 10.09.2024
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Year of Publication 10.09.2024
Patent
항-SIRP 알파 항체
VAN EENENNAAM HANS, HULSIK DAVID LUTJE, VAN ELSAS ANDREA, VINK PAUL, VOETS ERIK
Year of Publication 19.12.2019
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Year of Publication 19.12.2019
Patent
Crystal structure of the neutralizing Llama V(HH) D7 and its mode of HIV-1 gp120 interaction
Hinz, Andreas, Lutje Hulsik, David, Forsman, Anna, Koh, Willie Wee-Lee, Belrhali, Hassan, Gorlani, Andrea, de Haard, Hans, Weiss, Robin A, Verrips, Theo, Weissenhorn, Winfried
Published in PloS one (05.05.2010)
Published in PloS one (05.05.2010)
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Journal Article
Charged Multivesicular Body Protein 2B (CHMP2B) of the Endosomal Sorting Complex Required for Transport-III (ESCRT-III) Polymerizes into Helical Structures Deforming the Plasma Membrane
Bodon, Gilles, Chassefeyre, Romain, Pernet-Gallay, Karin, Martinelli, Nicolas, Effantin, Grégory, Hulsik, David Lutje, Belly, Agnès, Goldberg, Yves, Chatellard-Causse, Christine, Blot, Béatrice, Schoehn, Guy, Weissenhorn, Winfried, Sadoul, Rémy
Published in The Journal of biological chemistry (18.11.2011)
Published in The Journal of biological chemistry (18.11.2011)
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Journal Article
A novel efficient bispecific antibody format, combining a conventional antigen-binding fragment with a single domain antibody, avoids potential heavy-light chain mis-pairing
Huang, Shuyu, Segués, Aina, Hulsik, David Lutje, Zaiss, Dietmar M., Sijts, Alice J.A.M., van Duijnhoven, Sander M.J., van Elsas, Andrea
Published in Journal of immunological methods (01.08.2020)
Published in Journal of immunological methods (01.08.2020)
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Journal Article
Abstract 1203: Preclinical development of ADU-1805, a highly selective pan-allele anti-SIRPα antibody that blocks the SIRPα-CD47 innate immune checkpoint
Voets, Erik, Kreijtz, Joost, Vink, Paul, Hulsik, David Lutje, Parade, Mark, Spijkers, Sanne, Reinieren-Beeren, Inge, Rens, Joost, Janssen, Wout, Zandvoort, Peter van, Francica, Brian, Leong, Meredith, Elsas, Andrea van, Eenennaam, Hans van
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 2645: Development of a first in class APRIL fully blocking antibody BION-1301 for the treatment of multiple myeloma
Dulos, John, Driessen, Lilian, Snippert, Marc, Guadagnoli, Marco, Bertens, Astrid, Hulsik, David Lutje, Tzu, Tai Yu, Anderson, Kenneth, Medema, Jan Paul, Cameron, Kate, Eenennaam, Hans, Elsas, Andrea
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 1702: Assessment of pharmacology and toxicology of anti-CTLA-4 antibody (ADU-1604) in non-human primates and evaluation of local anti-CTLA-4 application
Hendriks, Maaike, Kreijtz, Joost, Vink, Paul, Hulsik, David Lutje, Lodewijks, Imke, Bertens, Astrid, Crommert, Jos van de, Habraken, Maurice, Janssen, Wout, Stammen-Vogelzang, Judith, Gardner, Olivia, Deng, Weiwen, Leong, Meredith, McWhirter, Sarah, Eenennaam, Hans van, Elsas, Andrea van
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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