Evidence for a Role of p38 Kinase in Hypoxia-inducible Factor 1-independent Induction of Vascular Endothelial Growth Factor Expression by Sodium Arsenite
Duyndam, Monique C A, Hulscher, Saskia T M, van der Wall, Elsken, Pinedo, Herbert M, Boven, Epie
Published in The Journal of biological chemistry (28.02.2003)
Published in The Journal of biological chemistry (28.02.2003)
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Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28
Vischer, Henry F., Hulshof, Janneke W., Hulscher, Saskia, Fratantoni, Silvina A., Verheij, Mark H.P., Victorina, Jane, Smit, Martine J., de Esch, Iwan J.P., Leurs, Rob
Published in Bioorganic & medicinal chemistry (15.01.2010)
Published in Bioorganic & medicinal chemistry (15.01.2010)
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4-benzyl-1H-imidazoles with oxazoline termini as histamine H-3 receptor agonists
Wijtmans, Maikel, Celanire, Sylvain, Snip, Erwin, Gillard, Michel R., Gelens, Edith, Collart, Philippe P., Venhuis, Bastiaan J., Christophe, Bernard, Hulscher, Saskia, van der Goot, Henk, Lebon, Florence, Timmerman, Henk, Bakker, Remko A., Lallemand, Benedicte I. L. F., Leurs, Rob, Talaga, Patrice E., de Esch, Iwan J. P.
Published in Journal of medicinal chemistry (22.05.2008)
Published in Journal of medicinal chemistry (22.05.2008)
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Identification of 4-(1H-Imidazol-4(5)-ylmethyl)pyridine (Immethridine) as a Novel, Potent, and Highly Selective Histamine H3 Receptor Agonist
Kitbunnadaj, Ruengwit, Zuiderveld, Obbe P, Christophe, Bernard, Hulscher, Saskia, Menge, Wiro M. P. B, Gelens, Edith, Snip, Erwin, Bakker, Remko A, Celanire, Sylvain, Gillard, Michel, Talaga, Patrice, Timmerman, Henk, Leurs, Rob
Published in Journal of medicinal chemistry (06.05.2004)
Published in Journal of medicinal chemistry (06.05.2004)
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Identification of 4-(1H-imidazol-4(5)-ylmethyl)pyridine (immethridine) as a novel, potent, and highly selective histamine H-3 receptor agonist
Kitbunnadaj, R, Zuiderveld, OP, Christophe, B, Hulscher, S, Menge, WMPB, Gelens, E, Snip, E, Bakker, RA, Celanire, S, Gillard, M, Talaga, P, Timmerman, H, Leurs, R
Published in Journal of medicinal chemistry (06.05.2004)
Published in Journal of medicinal chemistry (06.05.2004)
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Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H sub(4 and the ion channel serotonin 5-HT) sub(3)A
Verheij, Mark HP, De Graaf, Chris, De Kloe, Gerdien E, Nijmeijer, Saskia, Vischer, Henry F, Smits, Rogier A, Zuiderveld, Obbe P, Hulscher, Saskia, Silvestri, Linda, Thompson, Andrew J, Van Muijlwijk-Koezen, Jacqueline E, Lummis, Sarah CR, Leurs, Rob, De Esch, Iwan JP
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
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4-Benzyl-1H-imidazoles with Oxazoline Termini as Histamine H3 Receptor Agonists
Wijtmans, Maikel, Celanire, Sylvain, Snip, Erwin, Gillard, Michel R, Gelens, Edith, Collart, Philippe P, Venhuis, Bastiaan J, Christophe, Bernard, Hulscher, Saskia, Goot, Henk van der, Lebon, Florence, Timmerman, Henk, Bakker, Remko A, Lallemand, Bénédicte I. L. F, Leurs, Rob, Talaga, Patrice E, Esch, Iwan J. P. de
Published in Journal of medicinal chemistry (22.05.2008)
Published in Journal of medicinal chemistry (22.05.2008)
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CPT‐11 in human colon‐cancer cell lines and xenografts: Characterization of cellular sensitivity determinants
Jansen, Willy J.M., Zwart, Bas, Hulscher, Saskia T.M., Giaccone, Giuseppe, Pinedo, Herbert M., Boven, Epic
Published in International journal of cancer (27.01.1997)
Published in International journal of cancer (27.01.1997)
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4-Benzyl-1 H -imidazoles with Oxazoline Termini as Histamine H 3 Receptor Agonists
Wijtmans, Maikel, Celanire, Sylvain, Snip, Erwin, Gillard, Michel R., Gelens, Edith, Collart, Philippe P., Venhuis, Bastiaan J., Christophe, Bernard, Hulscher, Saskia, Goot, Henk van der, Lebon, Florence, Timmerman, Henk, Bakker, Remko A., Lallemand, Bénédicte I. L. F., Leurs, Rob, Talaga, Patrice E., Esch, Iwan J. P. de
Published in Journal of medicinal chemistry (01.05.2008)
Published in Journal of medicinal chemistry (01.05.2008)
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4-Benzyl-lH-imidazoles with Oxazoline Termini as Histamine H3 Receptor Agonists
WIJTMANS, Maikel, CELANIRE, Sylvain, LEBON, Florence, TIMMERMAN, Henk, BAKKER, Remko A, LALLEMAND, Bénédicte I. L. F, LEURS, Rob, TALAGA, Patrice E, DE ESCH, Iwan J. P, SNIP, Erwin, GILLARD, Michel R, GELENS, Edith, COLLART, Philippe P, VENHUIS, Bastiaan J, CHRISTOPHE, Bernard, HULSCHER, Saskia, VAN DER GOOT, Henk
Published in Journal of medicinal chemistry (2008)
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Published in Journal of medicinal chemistry (2008)
Journal Article
Histamine H3 receptor ligands with a 3-cyclobutoxy motif: a novel and versatile constraint of the classical 3-propoxy linker
Wijtmans, Maikel, Denonne, Frédéric, Célanire, Sylvain, Gillard, Michel, Hulscher, Saskia, Delaunoy, Christel, Van houtvin, Nathalie, Bakker, Remko A., Defays, Sabine, Gérard, Julien, Grooters, Luc, Hubert, Delphine, Timmerman, Henk, Leurs, Rob, Talaga, Patrice, de Esch, Iwan J. P., Provins, Laurent
Published in MedChemComm (01.07.2010)
Published in MedChemComm (01.07.2010)
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Histamine H3 receptor ligands with a 3-cyclobutoxy motif: a novel and versatile constraint of the classical 3-propoxy linkerElectronic supplementary information (ESI) available: Gradient programs, compound purities, pharmacological procedures, computational studies, synthetic procedures and NMR spectra. See DOI: 10.1039/c0md00056f
Wijtmans, Maikel, Denonne, Frédéric, Célanire, Sylvain, Gillard, Michel, Hulscher, Saskia, Delaunoy, Christel, Van houtvin, Nathalie, Bakker, Remko A, Defays, Sabine, Gérard, Julien, Grooters, Luc, Hubert, Delphine, Timmerman, Henk, Leurs, Rob, Talaga, Patrice, de Esch, Iwan J. P, Provins, Laurent
Year of Publication 01.07.2010
Year of Publication 01.07.2010
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A Flow-Through Fluorescence Polarization Detection System for Measuring GPCR-Mediated Modulation of cAMP Production
Kool, Jeroen, Van Marle, André, Hulscher, Saskia, Selman, Maurice, Van Iperen, Dick J., Altena, Klaas Van, Gillard, Michel, Bakker, Remko A., Irth, Hubertus, Leurs, Rob, Vermeulen, Nico P.E.
Published in Journal of biomolecular screening (01.12.2007)
Published in Journal of biomolecular screening (01.12.2007)
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Journal Article
Identification of 4-(1H-imidazol-4(5)-ylmethyl)pyridine (immethridine) as a novel, potent, and highly selective histamine H(3) receptor agonist
Kitbunnadaj, Ruengwit, Zuiderveld, Obbe P, Christophe, Bernard, Hulscher, Saskia, Menge, Wiro M P B, Gelens, Edith, Snip, Erwin, Bakker, Remko A, Celanire, Sylvain, Gillard, Michel, Talaga, Patrice, Timmerman, Henk, Leurs, Rob
Published in Journal of medicinal chemistry (06.05.2004)
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Published in Journal of medicinal chemistry (06.05.2004)
Journal Article
Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H4 and the ion channel serotonin 5-HT3A
Verheij, Mark H.P., de Graaf, Chris, de Kloe, Gerdien E., Nijmeijer, Saskia, Vischer, Henry F., Smits, Rogier A., Zuiderveld, Obbe P., Hulscher, Saskia, Silvestri, Linda, Thompson, Andrew J., van Muijlwijk-Koezen, Jacqueline E., Lummis, Sarah C.R., Leurs, Rob, de Esch, Iwan J.P.
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
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Effect of the insecticidal Galanthus nivalis agglutinin on metabolism and the activities of brush border enzymes in the rat small intestine
Pusztai, Arpad, Koninkx, Jos, Hendriks, Henno, Kok, Wouter, Hulscher, Saskia, Van Damme, Els J.M., Peumans, Willy J., Grant, George, Bardocz, Susan
Published in The Journal of nutritional biochemistry (01.12.1996)
Published in The Journal of nutritional biochemistry (01.12.1996)
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