The next-generation Open Targets Platform: reimagined, redesigned, rebuilt
Ochoa, David, Hercules, Andrew, Carmona, Miguel, Suveges, Daniel, Baker, Jarrod, Malangone, Cinzia, Lopez, Irene, Miranda, Alfredo, Cruz-Castillo, Carlos, Fumis, Luca, Bernal-Llinares, Manuel, Tsukanov, Kirill, Cornu, Helena, Tsirigos, Konstantinos, Razuvayevskaya, Olesya, Buniello, Annalisa, Schwartzentruber, Jeremy, Karim, Mohd, Ariano, Bruno, Martinez Osorio, Ricardo Esteban, Ferrer, Javier, Ge, Xiangyu, Machlitt-Northen, Sandra, Gonzalez-Uriarte, Asier, Saha, Shyamasree, Tirunagari, Santosh, Mehta, Chintan, Roldán-Romero, Juan María, Horswell, Stuart, Young, Sarah, Ghoussaini, Maya, Hulcoop, David G, Dunham, Ian, McDonagh, Ellen M
Published in Nucleic acids research (06.01.2023)
Published in Nucleic acids research (06.01.2023)
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Journal Article
A data science roadmap for open science organizations engaged in early-stage drug discovery
Edfeldt, Kristina, Edwards, Aled M., Engkvist, Ola, Günther, Judith, Hartley, Matthew, Hulcoop, David G., Leach, Andrew R., Marsden, Brian D., Menge, Amelie, Misquitta, Leonie, Müller, Susanne, Owen, Dafydd R., Schütt, Kristof T., Skelton, Nicholas, Steffen, Andreas, Tropsha, Alexander, Vernet, Erik, Wang, Yanli, Wellnitz, James, Willson, Timothy M., Clevert, Djork-Arné, Haibe-Kains, Benjamin, Schiavone, Lovisa Holmberg, Schapira, Matthieu
Published in Nature communications (05.07.2024)
Published in Nature communications (05.07.2024)
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Journal Article
Palladium-Catalyzed Annulation of Haloanilines and Halobenzamides Using Norbornadiene as an Acetylene Synthon: A Route to Functionalized Indolines, Isoquinolinones, and Indoles
Thansandote, Praew, Hulcoop, David G, Langer, Michael, Lautens, Mark
Published in Journal of organic chemistry (20.02.2009)
Published in Journal of organic chemistry (20.02.2009)
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Journal Article
Archetypes of Open Science Partnerships: connecting aims and means in open biomedical research collaborations
Norn, Maria Theresa, Priego, Laia Pujol, Ramos-Vielba, Irene, Ryan, Thomas Kjeldager, Conradsen, Marie Louise, Durcan, Thomas Martin, Hulcoop, David G., Edwards, Aled, Müller, Susanne
Published in Humanities & social sciences communications (11.09.2024)
Published in Humanities & social sciences communications (11.09.2024)
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Journal Article
A Palladium-Catalyzed Alkylation/Direct Arylation Synthesis of Nitrogen-Containing Heterocycles
Blaszykowski, Christophe, Aktoudianakis, Evangelos, Alberico, Dino, Bressy, Cyril, Hulcoop, David G, Jafarpour, Farnaz, Joushaghani, Arash, Laleu, Benoît, Lautens, Mark
Published in Journal of organic chemistry (07.03.2008)
Published in Journal of organic chemistry (07.03.2008)
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Journal Article
Open Targets Platform: new developments and updates two years on
Carvalho-Silva, Denise, Pierleoni, Andrea, Pignatelli, Miguel, Ong, ChuangKee, Fumis, Luca, Karamanis, Nikiforos, Carmona, Miguel, Faulconbridge, Adam, Hercules, Andrew, McAuley, Elaine, Miranda, Alfredo, Peat, Gareth, Spitzer, Michaela, Barrett, Jeffrey, Hulcoop, David G, Papa, Eliseo, Koscielny, Gautier, Dunham, Ian
Published in Nucleic acids research (08.01.2019)
Published in Nucleic acids research (08.01.2019)
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Journal Article
Human genetics evidence supports two-thirds of the 2021 FDA-approved drugs
Ochoa, David, Karim, Mohd, Ghoussaini, Maya, Hulcoop, David G., McDonagh, Ellen M., Dunham, Ian
Published in Nature reviews. Drug discovery (01.08.2022)
Published in Nature reviews. Drug discovery (01.08.2022)
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Journal Article
Open Targets Platform: supporting systematic drug–target identification and prioritisation
Ochoa, David, Hercules, Andrew, Carmona, Miguel, Suveges, Daniel, Gonzalez-Uriarte, Asier, Malangone, Cinzia, Miranda, Alfredo, Fumis, Luca, Carvalho-Silva, Denise, Spitzer, Michaela, Baker, Jarrod, Ferrer, Javier, Raies, Arwa, Razuvayevskaya, Olesya, Faulconbridge, Adam, Petsalaki, Eirini, Mutowo, Prudence, Machlitt-Northen, Sandra, Peat, Gareth, McAuley, Elaine, Ong, Chuang Kee, Mountjoy, Edward, Ghoussaini, Maya, Pierleoni, Andrea, Papa, Eliseo, Pignatelli, Miguel, Koscielny, Gautier, Karim, Mohd, Schwartzentruber, Jeremy, Hulcoop, David G, Dunham, Ian, McDonagh, Ellen M
Published in Nucleic acids research (08.01.2021)
Published in Nucleic acids research (08.01.2021)
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Journal Article
EMBL’s European Bioinformatics Institute (EMBL-EBI) in 2023
Thakur, Matthew, Buniello, Annalisa, Brooksbank, Catherine, Gurwitz, Kim T, Hall, Matthew, Hartley, Matthew, Hulcoop, David G, Leach, Andrew R, Marques, Diana, Martin, Maria, Mithani, Aziz, McDonagh, Ellen M, Mutasa-Gottgens, Euphemia, Ochoa, David, Perez-Riverol, Yasset, Stephenson, James, Varadi, Mihaly, Velankar, Sameer, Vizcaino, Juan Antonio, Witham, Rick, McEntyre, Johanna
Published in Nucleic acids research (05.01.2024)
Published in Nucleic acids research (05.01.2024)
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Journal Article
A Zinc Catalyzed C(sp3)−C(sp2) Suzuki–Miyaura Cross‐Coupling Reaction Mediated by Aryl‐Zincates
Procter, Richard J., Dunsford, Jay J., Rushworth, Philip J., Hulcoop, David G., Layfield, Richard A., Ingleson, Michael J.
Published in Chemistry : a European journal (13.11.2017)
Published in Chemistry : a European journal (13.11.2017)
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Journal Article
Development of Flexible and Scalable Routes to Two Phosphatidinylinositol-3-kinase Delta Inhibitors via a Common Intermediate Approach
Edney, Dean, Hulcoop, David G, Leahy, John H, Vernon, Lois E, Wipperman, Mark D, Bream, Robert N, Webb, Michael R
Published in Organic process research & development (16.03.2018)
Published in Organic process research & development (16.03.2018)
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Journal Article
Development of Synthetic Routes, via a Tropinone Intermediate, to a Long-Acting Muscarinic Antagonist for the Treatment of Respiratory Disease
Bream, Robert N, Hayes, Doug, Hulcoop, David G, Whiteman, Alexandra J
Published in Organic process research & development (19.04.2013)
Published in Organic process research & development (19.04.2013)
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Journal Article
Palladium-Catalysed Cross-Coupling of Vinyldisiloxanes with Benzylic and Allylic Halides and Sulfonates
Frye, Elizabeth C., O' Connor, Cornelius J., Twigg, David G., Elbert, Bryony, Laraia, Luca, Hulcoop, David G., Venkitaraman, Ashok R., Spring, David R.
Published in Chemistry : a European journal (09.07.2012)
Published in Chemistry : a European journal (09.07.2012)
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Journal Article
Manganese(iii) acetate mediated synthesis of oxygen heterocycles. Influence of copper(ii) salts on product distributionElectronic supplementary information (ESI) available: spectroscopic data. See http://www.rsc.org/suppdata/ob/b4/b402411g
Hulcoop, David G., Sheldrake, Helen M., Burton, Jonathan W.
Published in Organic & biomolecular chemistry (2004)
Published in Organic & biomolecular chemistry (2004)
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Journal Article
Oxidative radical cyclisations for the synthesis of gamma-lactones
Powell, Luke H., Docherty, Paul H., Hulcoop, David G., Kemmitt, Paul D., Burton, Jonathan W.
Published in Chemical communications (Cambridge, England) (14.06.2008)
Published in Chemical communications (Cambridge, England) (14.06.2008)
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Journal Article
Development of a Selective Friedel–Crafts Alkylation Surrogate: Safe Operating Conditions through Mechanistic Understanding
Bream, Robert N, Hulcoop, David G, Gooding, Steve J, Watson, Simon A, Blore, Charlotte
Published in Organic process research & development (21.12.2012)
Published in Organic process research & development (21.12.2012)
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Journal Article
Aryl-Aryl Bond Formation by the Fluoride-Free Cross-Coupling of Aryldisiloxanes with Aryl Bromides
Boehner, Christine M., Frye, Elizabeth C., O'Connell, Kieron M. G., Galloway, Warren R. J. D., Sore, Hannah F., Dominguez, Patricia Garcia, Norton, David, Hulcoop, David G., Owen, Martin, Turner, Gillian, Crawford, Claire, Horsley, Helen, Spring, David R.
Published in Chemistry : a European journal (18.11.2011)
Published in Chemistry : a European journal (18.11.2011)
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