CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans
Beatty, Gregory L., Chiorean, Elena G., Fishman, Matthew P., Saboury, Babak, Teitelbaum, Ursina R., Sun, Weijing, Huhn, Richard D., Song, Wenru, Li, Dongguang, Sharp, Leslie L., Torigian, Drew A., O'Dwyer, Peter J., Vonderheide, Robert H.
Published in Science (American Association for the Advancement of Science) (25.03.2011)
Published in Science (American Association for the Advancement of Science) (25.03.2011)
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Clinical Activity and Immune Modulation in Cancer Patients Treated With CP-870,893, a Novel CD40 Agonist Monoclonal Antibody
VONDERHEIDE, Robert H, FLAHERTY, Keith T, GREEN, Stephanie, O'DWYER, Peter J, RUNNING, Kelli L, HUHN, Richard D, ANTONIA, Scott J, KHALIL, Magi, STUMACHER, Molly S, BAJOR, David L, HUTNICK, Natalie A, SULLIVAN, Patricia, MAHANY, J. Joseph, GALLAGHER, Maryann, KRAMER, Amy
Published in Journal of clinical oncology (01.03.2007)
Published in Journal of clinical oncology (01.03.2007)
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A randomized, controlled trial evaluating the efficacy and safety of BTH1677 in combination with bevacizumab, carboplatin, and paclitaxel in first-line treatment of advanced non-small cell lung cancer
Engel-Riedel, Walburga, Lowe, Jamie, Mattson, Paulette, Richard Trout, J, Huhn, Richard D, Gargano, Michele, Patchen, Myra L, Walsh, Richard, Trinh, My My, Dupuis, Mariève, Schneller, Folker
Published in Journal for immunotherapy of cancer (27.02.2018)
Published in Journal for immunotherapy of cancer (27.02.2018)
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Immune Pharmacodynamic Responses of the Novel Cancer Immunotherapeutic Imprime PGG in Healthy Volunteers
Bose, Nandita, Ottoson, Nadine R, Qiu, Xiaohong, Harrison, Ben, Lowe, Jamie R, Uhlik, Mark T, Rathmann, Blaine T, Kangas, Takashi O, Jordan, Lindsay R, Ertelt, Kathleen E, Jonas, Adria Bykowski, Walsh, Richard M, Chan, Anissa S H, Fulton, Ross B, Leonardo, Steven M, Fraser, Kathryn A, Gorden, Keith B, Matson, Mark A, Graff, Jeremy R, Huhn, Richard D
Published in The Journal of immunology (1950) (15.05.2019)
Published in The Journal of immunology (1950) (15.05.2019)
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Pharmacokinetics and leukocyte responses of recombinant human interleukin-10
RADWANSKI, E, CHAKRABORTY, A, VAN WART, S, HUHN, R. D, CUTLER, D. L, AFFRIME, M. B, JUSKO, W. J
Published in Pharmaceutical research (01.12.1998)
Published in Pharmaceutical research (01.12.1998)
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Combination anti-CD137 and anti-CD40 antibody therapy in murine myc-driven hematological cancers
Westwood, Jennifer A, Matthews, Geoffrey M, Shortt, Jake, Faulkner, David, Pegram, Hollie J, Duong, Connie P.M, Chesi, Marta, Bergsagel, P. Leif, Sharp, Leslie L, Huhn, Richard D, Darcy, Phillip K, Johnstone, Ricky W, Kershaw, Michael H
Published in Leukemia research (01.08.2014)
Published in Leukemia research (01.08.2014)
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High-dose cyclophosphamide with autologous lymphocyte–depleted peripheral blood stem cell (PBSC) support for treatment of refractory chronic autoimmune thrombocytopenia
Huhn, Richard D., Fogarty, Patrick F., Nakamura, Ryotaro, Read, Elizabeth J., Leitman, Susan F., Rick, Margaret E., Kimball, Janice, Greene, Adeira, Hansmann, Kristin, Gratwohl, Alois, Young, Neal, Barrett, A. John, Dunbar, Cynthia E.
Published in Blood (01.01.2003)
Published in Blood (01.01.2003)
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A Phase 1 Study Evaluating BI 765063, a First in Class Selective Myeloid Sirpa Inhibitor, As Stand-Alone and in Combination with BI 754091, a Programmed Death-1 (PD-1) Inhibitor, in Patients with Advanced Solid Tumours
Delord, Jean-Pierre, Kotecki, Nuria, Marabelle, Aurelien, Vinceneux, Armelle, Korakis, Iphigenie, Jungels, Christiane, Champiat, Stéphane, Huhn, Richard D., Poirier, Nicolas, Costantini, Dominique, Vasseur, Bérangère, Cassier, Philippe A.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Abstract A26: Imprime PGG improves the efficacy of carboplatin, paclitaxel, and cetuximab chemoimmunotherapy of advanced non-small cell lung cancer (NSCLC)
Thomas, Michael, Sadjadian, Parvis, Kollmeier, Jens, Hao, Zhonglin, Patchen, Myra, Lowe, Jamie, Mattson, Paulette, Huhn, Richard D., Bose, Nandita, Antonysamy, Mary, Gargano, Michele, Gordon, Keith, Schneller, Folker
Published in Clinical cancer research (15.01.2014)
Published in Clinical cancer research (15.01.2014)
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Effect of montelukast on single-dose theophylline pharmacokinetics
Malmstrom, K, Schwartz, J, Reiss, T F, Sullivan, T J, Reese, J H, Jauregui, L, Miller, K, Scott, M, Shingo, S, Peszek, I, Larson, P, Ebel, D, Hunt, T L, Huhn, R D, Bachmann, K
Published in American journal of therapeutics (01.05.1998)
Published in American journal of therapeutics (01.05.1998)
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A Phase III open-label, randomized, multicenter study of imprime pgg in combination with cetuximab in patients with kras wild type metastatic colorectal cancer
Meyerhardt, Jeffrey A, Grady, Michele M, Lowe, Jamie N, Gargano, Michele A, Huhn, Richard D, Braun, Ada H
Published in Journal for immunotherapy of cancer (06.11.2014)
Published in Journal for immunotherapy of cancer (06.11.2014)
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Journal Article
Pharmacodynamics of subcutaneous recombinant human interleukin-10 in healthy volunteers
Huhn, R D, Radwanski, E, Gallo, J, Affrime, M B, Sabo, R, Gonyo, G, Monge, A, Cutler, D L
Published in Clinical pharmacology and therapeutics (01.08.1997)
Published in Clinical pharmacology and therapeutics (01.08.1997)
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Pharmacokinetics and Immunomodulatory Properties of Intravenously Administered Recombinant Human Interleukin-10 in Healthy Volunteers
Huhn, Richard D., Radwanski, Elaine, O'Connell, Sean M., Sturgill, Marc G., Clarke, Laura, Cody, Ronald P., Affrime, Melton B., Cutler, David L.
Published in Blood (15.01.1996)
Published in Blood (15.01.1996)
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Therapeutic effects and pharmacokinetics of recombinant human granulocyte-macrophage colony-stimulating factor in childhood cancer patients receiving myelosuppressive chemotherapy
Furman, W L, Fairclough, D L, Huhn, R D, Pratt, C B, Stute, N, Petros, W P, Evans, W E, Bowman, L C, Douglass, E C, Santana, V M
Published in Journal of clinical oncology (01.06.1991)
Published in Journal of clinical oncology (01.06.1991)
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Pharmacokinetics of intravenous recombinant human granulocyte colony‐stimulating factor (rhG‐CSF) in children receiving myelosuppressive cancer chemotherapy: Clearance increases in relation to absolute neutrophil count with repeated dosing
Sturgill, Marc G., Huhn, Richard D., Drachtman, Richard A., Ettinger, Alice G., Ettinger, Lawrence J.
Published in American journal of hematology (01.02.1997)
Published in American journal of hematology (01.02.1997)
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