Scaffolds obtained from decellularized human extrahepatic bile ducts support organoids to establish functional biliary tissue in a dish
Willemse, Jorke, Roos, Floris J. M., Voogt, Iris J., Schurink, Ivo J., Bijvelds, Marcel, Jonge, Hugo R., Laan, Luc J. W., Jonge, Jeroen, Verstegen, Monique M. A.
Published in Biotechnology and bioengineering (01.02.2021)
Published in Biotechnology and bioengineering (01.02.2021)
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Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease
Kelly, Jennifer, Al-Rammahi, Miran, Daly, Kristian, Flanagan, Paul K., Urs, Arun, Cohen, Marta C., di Stefano, Gabriella, Bijvelds, Marcel J. C., Sheppard, David N., de Jonge, Hugo R., Seidler, Ursula E., Shirazi-Beechey, Soraya P.
Published in Scientific reports (21.04.2022)
Published in Scientific reports (21.04.2022)
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Journal Article
Impact of hypoxia and AMPK on CFTR-mediated bicarbonate secretion in human cholangiocyte organoids
Roos, Floris J M, Bijvelds, Marcel J C, Verstegen, Monique M A, Roest, Henk P, Metselaar, Herold J, Polak, Wojciech G, Jonge, Hugo R de, IJzermans, Jan N M, Laan, Luc J W van der
Published in American journal of physiology: Gastrointestinal and liver physiology (01.05.2021)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.05.2021)
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Journal Article
Rescue of murine F508del CFTR activity in native intestine by low temperature and proteasome inhibitors
Wilke, Martina, Bot, Alice, Jorna, Huub, Scholte, Bob J, de Jonge, Hugo R
Published in PloS one (21.12.2012)
Published in PloS one (21.12.2012)
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Journal Article
A functional CFTR assay using primary cystic fibrosis intestinal organoids
Dekkers, Johanna F, Wiegerinck, Caroline L, de Jonge, Hugo R, Bronsveld, Inez, Janssens, Hettie M, de Winter-de Groot, Karin M, Brandsma, Arianne M, de Jong, Nienke W M, Bijvelds, Marcel J C, Scholte, Bob J, Nieuwenhuis, Edward E S, van den Brink, Stieneke, Clevers, Hans, van der Ent, Cornelis K, Middendorp, Sabine, Beekman, Jeffrey M
Published in Nature medicine (01.07.2013)
Published in Nature medicine (01.07.2013)
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Journal Article
Mini-gut: a promising model for drug development
Yin, Yue-Bang, de Jonge, Hugo R., Wu, Xin, Yin, Yu-Long
Published in Drug discovery today (01.09.2019)
Published in Drug discovery today (01.09.2019)
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Journal Article
Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease
Verstegen, Monique M. A., Roos, Floris J. M., Burka, Ksenia, Gehart, Helmuth, Jager, Myrthe, de Wolf, Maaike, Bijvelds, Marcel J. C., de Jonge, Hugo R., Ardisasmita, Arif I., van Huizen, Nick A., Roest, Henk P., de Jonge, Jeroen, Koch, Michael, Pampaloni, Francesco, Fuchs, Sabine A., Schene, Imre F., Luider, Theo M., van der Doef, Hubert P. J., Bodewes, Frank A. J. A., de Kleine, Ruben H. J., Spee, Bart, Kremers, Gert-Jan, Clevers, Hans, IJzermans, Jan N. M., Cuppen, Edwin, van der Laan, Luc J. W.
Published in Scientific reports (14.12.2020)
Published in Scientific reports (14.12.2020)
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Journal Article
Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR
Bose, Samuel J, Bijvelds, Marcel J C, Wang, Yiting, Liu, Jia, Cai, Zhiwei, Bot, Alice G M, de Jonge, Hugo R, Sheppard, David N
Published in American journal of physiology. Lung cellular and molecular physiology (01.07.2019)
Published in American journal of physiology. Lung cellular and molecular physiology (01.07.2019)
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Journal Article
Assessing cell-specific effects of genetic variations using tRNA microarrays
Polte, Christine, Wedemeyer, Daniel, Oliver, Kathryn E, Wagner, Johannes, Bijvelds, Marcel J C, Mahoney, John, de Jonge, Hugo R, Sorscher, Eric J, Ignatova, Zoya
Published in BMC genomics (16.07.2019)
Published in BMC genomics (16.07.2019)
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Journal Article
Mouse models of cystic fibrosis: Phenotypic analysis and research applications
Wilke, Martina, Buijs-Offerman, Ruvalic M, Aarbiou, Jamil, Colledge, William H, Sheppard, David N, Touqui, Lhousseine, Bot, Alice, Jorna, Huub, De Jonge, Hugo R, Scholte, Bob J
Published in Journal of cystic fibrosis (01.06.2011)
Published in Journal of cystic fibrosis (01.06.2011)
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Journal Article
Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium
Angyal, Dora, Groeneweg, Tessa A, Leung, Anny, Desain, Max, Dulla, Kalyan, de Jonge, Hugo R, Bijvelds, Marcel J C
Published in Cellular & molecular biology letters (23.01.2024)
Published in Cellular & molecular biology letters (23.01.2024)
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Journal Article
Bicarbonate Transport in Cystic Fibrosis and Pancreatitis
Angyal, Dora, Bijvelds, Marcel J C, Bruno, Marco J, Peppelenbosch, Maikel P, de Jonge, Hugo R
Published in Cells (Basel, Switzerland) (24.12.2021)
Published in Cells (Basel, Switzerland) (24.12.2021)
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Journal Article
Folding of CFTR Is Predominantly Cotranslational
Kleizen, Bertrand, van Vlijmen, Thijs, de Jonge, Hugo R., Braakman, Ineke
Published in Molecular cell (28.10.2005)
Published in Molecular cell (28.10.2005)
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Journal Article
Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice
Cunningham, Rochelle, Esmaili, Ali, Brown, Eric, Biswas, Rajat S, Murtazina, Rakhilya, Donowitz, Mark, Dijkman, Henry B, van der Vlag, Johan, Hogema, Boris M, De Jonge, Hugo R, Shenolikar, Shirish, Wade, James B, Weinman, Edward J
Published in American journal of physiology. Renal physiology (01.04.2008)
Published in American journal of physiology. Renal physiology (01.04.2008)
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Journal Article
Compartmentalized Accumulation of cAMP near Complexes of Multidrug Resistance Protein 4 (MRP4) and Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Contributes to Drug-induced Diarrhea
Moon, Changsuk, Zhang, Weiqiang, Ren, Aixia, Arora, Kavisha, Sinha, Chandrima, Yarlagadda, Sunitha, Woodrooffe, Koryse, Schuetz, John D., Valasani, Koteswara Rao, de Jonge, Hugo R., Shanmukhappa, Shiva Kumar, Shata, Mohamed Tarek M., Buddington, Randal K., Parthasarathi, Kaushik, Naren, Anjaparavanda P.
Published in The Journal of biological chemistry (01.05.2015)
Published in The Journal of biological chemistry (01.05.2015)
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Journal Article
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice
Singh, Anurag Kumar, Riederer, Brigitte, Krabbenhöft, Anja, Rausch, Brigitte, Bonhagen, Janina, Lehmann, Ulrich, de Jonge, Hugo R, Donowitz, Mark, Yun, Chris, Weinman, Edward J, Kocher, Olivier, Hogema, Boris M, Seidler, Ursula
Published in The Journal of clinical investigation (01.03.2009)
Published in The Journal of clinical investigation (01.03.2009)
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Journal Article
A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations
van Vugt, Anke H M, Bijvelds, Marcel J C, de Jonge, Hugo R, Meijsen, Kelly F, Restin, Tanja, Bryant, Manuel B, Ballauff, Antje, Koot, Bart, Müller, Thomas, Houwen, Roderick H J, Janecke, Andreas R, Middendorp, Sabine
Published in Clinical and translational gastroenterology (18.11.2021)
Published in Clinical and translational gastroenterology (18.11.2021)
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Journal Article
Biopolymer Extracted from Anadenanthera colubrina (Red Angico Gum) Exerts Therapeutic Potential in Mice: Antidiarrheal Activity and Safety Assessment
Araújo, Thiago S L, de Oliveira, Taiane M, de Sousa, Nayara A, Souza, Luan K M, Sousa, Francisca B M, de Oliveira, Ana P, Nicolau, Lucas A D, da Silva, Alfredo A V, Araújo, Alyne R, Magalhães, Pedro J C, Vasconcelos, Daniel F P, de Jonge, Hugo R, Souza, Marcellus H L P, Silva, Durcilene A, Paula, Regina C M, Medeiros, Jand Venes R
Published in Pharmaceuticals (Basel, Switzerland) (18.01.2020)
Published in Pharmaceuticals (Basel, Switzerland) (18.01.2020)
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