Impaired Intestinal Farnesoid X Receptor Signaling in Cystic Fibrosis Mice
Ikpa, Pauline T, Doktorova, Marcela, Meijsen, Kelly F, Nieuwenhuijze, Natascha D.A, Verkade, Henkjan J, Jonker, Johan W, de Jonge, Hugo R, Bijvelds, Marcel J.C
Published in Cellular and molecular gastroenterology and hepatology (01.01.2020)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2020)
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Journal Article
cGMP inhibition of type 3 phosphodiesterase is the major mechanism by which C-type natriuretic peptide activates CFTR in the shark rectal gland
De Jonge, Hugo R, Tilly, Ben C, Hogema, Boris M, Pfau, Daniel J, Kelley, Catherine A, Kelley, Megan H, Melita, August M, Morris, Montana T, Viola, Ryan M, Forrest, Jr, John N
Published in American Journal of Physiology: Cell Physiology (15.02.2014)
Published in American Journal of Physiology: Cell Physiology (15.02.2014)
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Journal Article
NHERF2 is necessary for basal activity, second messenger inhibition, and LPA stimulation of NHE3 in mouse distal ileum
Murtazina, Rakhilya, Kovbasnjuk, Olga, Chen, Tian-E, Zachos, Nicholas C, Chen, Yeuping, Kocinsky, Hetal S, Hogema, Boris M, Seidler, Ursula, de Jonge, Hugo R, Donowitz, Mark
Published in American Journal of Physiology: Cell Physiology (01.07.2011)
Published in American Journal of Physiology: Cell Physiology (01.07.2011)
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Journal Article
Human enteroids: preclinical models of non-inflammatory diarrhea
Kovbasnjuk, Olga, Zachos, Nicholas C, In, Julie, Foulke-Abel, Jennifer, Ettayebi, Khalil, Hyser, Joseph M, Broughman, James R, Zeng, Xi-Lei, Middendorp, Sabine, de Jonge, Hugo R, Estes, Mary K, Donowitz, Mark
Published in Stem cell research & therapy (20.12.2013)
Published in Stem cell research & therapy (20.12.2013)
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Journal Article
Expression of cGMP-Dependent Protein Kinase I and Phosphorylation of Its Substrate, Vasodilator-Stimulated Phosphoprotein, in Human Endothelial Cells of Different Origin
Draijer, Richard, Vaandrager, Arie B, Nolte, Christine, de Jonge, Hugo R, Walter, Ulrich, van Hinsbergh, Victor W.M
Published in Circulation research (01.11.1995)
Published in Circulation research (01.11.1995)
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Journal Article
Value of Organoids from Comparative Epithelia Models
Schwarz, Julia S, de Jonge, Hugo R, Forrest, Jr, John N
Published in The Yale journal of biology & medicine (01.12.2015)
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Published in The Yale journal of biology & medicine (01.12.2015)
Journal Article
Tissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) null mice. cAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP in ileum versus proximal tubule
Murtazina, Rakhilya, Kovbasnjuk, Olga, Zachos, Nicholas C, Li, Xuhang, Chen, Yueping, Hubbard, Ann, Hogema, Boris M, Steplock, Deborah, Seidler, Ursula, Hoque, Kazi M, Tse, Chung Ming, De Jonge, Hugo R, Weinman, Edward J, Donowitz, M
Published in The Journal of biological chemistry (24.08.2007)
Published in The Journal of biological chemistry (24.08.2007)
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Journal Article
rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice
Vidović, Dragana, Carlon, Marianne S, da Cunha, Mélanie F, Dekkers, Johanna F, Hollenhorst, Monika I, Bijvelds, Marcel J C, Ramalho, Anabela S, Van den Haute, Chris, Ferrante, Marc, Baekelandt, Veerle, Janssens, Hettie M, De Boeck, Kris, Sermet-Gaudelus, Isabelle, de Jonge, Hugo R, Gijsbers, Rik, Beekman, Jeffrey M, Edelman, Aleksander, Debyser, Zeger
Published in American journal of respiratory and critical care medicine (01.02.2016)
Published in American journal of respiratory and critical care medicine (01.02.2016)
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Journal Article
β 2 -Adrenergic receptor agonists activate CFTR in intestinal organoids and subjects with cystic fibrosis
Vijftigschild, Lodewijk A.W., Berkers, Gitte, Dekkers, Johanna F., Zomer-van Ommen, Domenique D., Matthes, Elizabeth, Kruisselbrink, Evelien, Vonk, Annelotte, Hensen, Chantal E., Heida-Michel, Sabine, Geerdink, Margot, Janssens, Hettie M., van de Graaf, Eduard A., Bronsveld, Inez, de Winter-de Groot, Karin M., Majoor, Christof J., Heijerman, Harry G.M., de Jonge, Hugo R., Hanrahan, John W., van der Ent, Cornelis K., Beekman, Jeffrey M.
Published in The European respiratory journal (28.09.2016)
Published in The European respiratory journal (28.09.2016)
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Journal Article
Autophosphorylation of cGMP-dependent Protein Kinase Type II
Vaandrager, Arie B., Hogema, Boris M., Edixhoven, Marcel, van den Burg, Caroline M.M., Bot, Alice G.M., Klatt, Peter, Ruth, Peter, Hofmann, Franz, Van Damme, Jozef, Vandekerckhove, Joel, de Jonge, Hugo R.
Published in The Journal of biological chemistry (01.08.2003)
Published in The Journal of biological chemistry (01.08.2003)
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Journal Article
Ursodeoxycholate modulates bile flow and bile salt pool independently from the cystic fibrosis transmembrane regulator (Cftr) in mice
Bodewes, Frank A J A, Wouthuyzen-Bakker, Marjan, Bijvelds, Marcel J, Havinga, Rick, de Jonge, Hugo R, Verkade, Henkjan J
Published in American journal of physiology: Gastrointestinal and liver physiology (01.05.2012)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.05.2012)
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Journal Article
Electrophysiological studies of malaria parasite-infected erythrocytes: Current status
Staines, Henry M., Alkhalil, Abdulnaser, Allen, Richard J., De Jonge, Hugo R., Derbyshire, Elvira, Egée, Stéphane, Ginsburg, Hagai, Hill, David A., Huber, Stephan M., Kirk, Kiaran, Lang, Florian, Lisk, Godfrey, Oteng, Eugene, Pillai, Ajay D., Rayavara, Kempaiah, Rouhani, Sherin, Saliba, Kevin J., Shen, Crystal, Solomon, Tsione, Thomas, Serge L.Y., Verloo, Patrick, Desai, Sanjay A.
Published in International journal for parasitology (01.04.2007)
Published in International journal for parasitology (01.04.2007)
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Journal Article
Tissue-specific Regulation of Sodium/Proton Exchanger Isoform 3 Activity in Na+/H+ Exchanger Regulatory Factor 1 (NHERF1) Null Mice
Murtazina, Rakhilya, Kovbasnjuk, Olga, Zachos, Nicholas C., Li, Xuhang, Chen, Yueping, Hubbard, Ann, Hogema, Boris M., Steplock, Deborah, Seidler, Ursula, Hoque, Kazi M., Tse, Chung Ming, De Jonge, Hugo R., Weinman, Edward J., Donowitz, M.
Published in The Journal of biological chemistry (24.08.2007)
Published in The Journal of biological chemistry (24.08.2007)
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Journal Article
Distinct and specific functions of cGMP-dependent protein kinases
Lohmann, Suzanne M., Vaandrager, Arie B., Smolenski, Albert, Walter, Ulrich, De Jonge, Hugo R.
Published in Trends in Biochemical Sciences (01.08.1997)
Published in Trends in Biochemical Sciences (01.08.1997)
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Book Review
Journal Article
Ex vivo CF diagnosis by intestinal current measurements (ICM) in small aperture, circulating Ussing chambers
de Jonge, Hugo R., Ballmann, Manfred, Veeze, Henk, Bronsveld, Inez, Stanke, Frauke, Tümmler, Burkhard, Sinaasappel, Maarten
Published in Journal of cystic fibrosis (01.08.2004)
Published in Journal of cystic fibrosis (01.08.2004)
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Journal Article
Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis
Poschet, Jens F, Timmins, Graham S, Taylor-Cousar, Jennifer L, Ornatowski, Wojciech, Fazio, Joseph, Perkett, Elizabeth, Wilson, Kari R, Yu, Hongwei D, de Jonge, Hugo R, Deretic, Vojo
Published in American journal of physiology. Lung cellular and molecular physiology (01.09.2007)
Published in American journal of physiology. Lung cellular and molecular physiology (01.09.2007)
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Journal Article