Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
Siddiqi, Farah H., Menzies, Fiona M., Lopez, Ana, Stamatakou, Eleanna, Karabiyik, Cansu, Ureshino, Rodrigo, Ricketts, Thomas, Jimenez-Sanchez, Maria, Esteban, Miguel Angel, Lai, Liangxue, Tortorella, Micky D., Luo, Zhiwei, Liu, Hao, Metzakopian, Emmanouil, Fernandes, Hugo J. R., Bassett, Andrew, Karran, Eric, Miller, Bruce L., Fleming, Angeleen, Rubinsztein, David C.
Published in Nature communications (18.04.2019)
Published in Nature communications (18.04.2019)
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A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells
Barradas, Ana M.C, Fernandes, Hugo A.M, Groen, Nathalie, Chai, Yoke Chin, Schrooten, Jan, van de Peppel, Jeroen, van Leeuwen, Johannes P.T.M, van Blitterswijk, Clemens A, de Boer, Jan
Published in Biomaterials (01.04.2012)
Published in Biomaterials (01.04.2012)
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Single-Cell Transcriptomics of Parkinson’s Disease Human In Vitro Models Reveals Dopamine Neuron-Specific Stress Responses
Fernandes, Hugo J.R., Patikas, Nikolaos, Foskolou, Stefanie, Field, Sarah F., Park, Jong-Eun, Byrne, Meg L., Bassett, Andrew R., Metzakopian, Emmanouil
Published in Cell reports (Cambridge) (13.10.2020)
Published in Cell reports (Cambridge) (13.10.2020)
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Differential Representations of Prior and Likelihood Uncertainty in the Human Brain
Vilares, Iris, Howard, James D., Fernandes, Hugo L., Gottfried, Jay A., Kording, Konrad P.
Published in Current biology (25.09.2012)
Published in Current biology (25.09.2012)
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Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons
Zambon, Federico, Cherubini, Marta, Fernandes, Hugo J R, Lang, Charmaine, Ryan, Brent J, Volpato, Viola, Bengoa-Vergniory, Nora, Vingill, Siv, Attar, Moustafa, Booth, Heather D E, Haenseler, Walther, Vowles, Jane, Bowden, Rory, Webber, Caleb, Cowley, Sally A, Wade-Martins, Richard
Published in Human molecular genetics (15.06.2019)
Published in Human molecular genetics (15.06.2019)
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MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development
Parada, Guillermo E, Munita, Roberto, Georgakopoulos-Soares, Ilias, Fernandes, Hugo J R, Kedlian, Veronika R, Metzakopian, Emmanouil, Andres, Maria Estela, Miska, Eric A, Hemberg, Martin
Published in Genome Biology (22.01.2021)
Published in Genome Biology (22.01.2021)
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ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons
Fernandes, Hugo J.R., Hartfield, Elizabeth M., Christian, Helen C., Emmanoulidou, Evangelia, Zheng, Ying, Booth, Heather, Bogetofte, Helle, Lang, Charmaine, Ryan, Brent J., Sardi, S. Pablo, Badger, Jennifer, Vowles, Jane, Evetts, Samuel, Tofaris, George K., Vekrellis, Kostas, Talbot, Kevin, Hu, Michele T., James, William, Cowley, Sally A., Wade-Martins, Richard
Published in Stem cell reports (08.03.2016)
Published in Stem cell reports (08.03.2016)
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CRISPR-Cas9 genetic screen leads to the discovery of L-Moses, a KAT2B inhibitor that attenuates Tunicamycin-mediated neuronal cell death
Pavlou, Sofia, Foskolou, Stefanie, Patikas, Nikolaos, Field, Sarah F., Papachristou, Evangelia K., Santos, Clive D’, Edwards, Abigail R., Kishore, Kamal, Ansari, Rizwan, Rajan, Sandeep S., Fernandes, Hugo J. R., Metzakopian, Emmanouil
Published in Scientific reports (09.03.2023)
Published in Scientific reports (09.03.2023)
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Bioactive Tape With BMP-2 Binding Peptides Captures Endogenous Growth Factors and Accelerates Healing After Anterior Cruciate Ligament Reconstruction
Crispim, João F, Fu, Sai C, Lee, Yuk W, Fernandes, Hugo A M, Jonkheijm, Pascal, Yung, Patrick S H, Saris, Daniël B F
Published in The American journal of sports medicine (01.10.2018)
Published in The American journal of sports medicine (01.10.2018)
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Journal Article
Prolotherapy Induces an Inflammatory Response in Human Tenocytes In Vitro
Ekwueme, Emmanuel C., Mohiuddin, Mahir, Yarborough, Jazmin A., Brolinson, P. Gunnar, Docheva, Denitsa, Fernandes, Hugo A. M., Freeman, Joseph W.
Published in Clinical orthopaedics and related research (01.08.2017)
Published in Clinical orthopaedics and related research (01.08.2017)
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Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease
Vazquez-Arango, Pilar, Vowles, Jane, Browne, Cathy, Hartfield, Elizabeth, Fernandes, Hugo J R, Mandefro, Berhan, Sareen, Dhruv, James, William, Wade-Martins, Richard, Cowley, Sally A, Murphy, Shona, O'Reilly, Dawn
Published in Nucleic acids research (15.12.2016)
Published in Nucleic acids research (15.12.2016)
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Variant‐specific effects of GBA1 mutations on dopaminergic neuron proteostasis
Onal, G., Yalçın‐Çakmaklı, G., Özçelik, C. E., Boussaad, I., Şeker, U. Ö. Ş., Fernandes, Hugo J. R., Demir, H., Krüger, R., Elibol, B., Dökmeci, S., Salman, M. M.
Published in Journal of neurochemistry (01.09.2024)
Published in Journal of neurochemistry (01.09.2024)
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Osteoinductive ceramics as a synthetic alternative to autologous bone grafting
Yuan, Huipin, Fernandes, Hugo, Habibovic, Pamela, de Boer, Jan, Barradas, Ana M. C., de Ruiter, Ad, Walsh, William R., van Blitterswijk, Clemens A., de Bruijn, Joost D., Langer, Robert
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2010)
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Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson’s disease GBA-N370S dopamine neurons
Bogetofte, Helle, Ryan, Brent J., Jensen, Pia, Schmidt, Sissel I., Vergoossen, Dana L.E., Barnkob, Mike B., Kiani, Lisa N., Chughtai, Uroosa, Heon-Roberts, Rachel, Caiazza, Maria Claudia, McGuinness, William, Márquez-Gómez, Ricardo, Vowles, Jane, Bunn, Fiona S., Brandes, Janine, Kilfeather, Peter, Connor, Jack P., Fernandes, Hugo J.R., Caffrey, Tara M., Meyer, Morten, Cowley, Sally A., Larsen, Martin R., Wade-Martins, Richard
Published in Cell reports (Cambridge) (28.03.2023)
Published in Cell reports (Cambridge) (28.03.2023)
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