Identification and characterization of essential genes in the human genome
Wang, Tim, Birsoy, Kivanç, Hughes, Nicholas W., Krupczak, Kevin M., Post, Yorick, Wei, Jenny J., Lander, Eric S., Sabatini, David M.
Published in Science (American Association for the Advancement of Science) (27.11.2015)
Published in Science (American Association for the Advancement of Science) (27.11.2015)
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Journal Article
Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras
Wang, Tim, Yu, Haiyan, Hughes, Nicholas W., Liu, Bingxu, Kendirli, Arek, Klein, Klara, Chen, Walter W., Lander, Eric S., Sabatini, David M.
Published in Cell (23.02.2017)
Published in Cell (23.02.2017)
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Journal Article
The observed recent surface air temperature development across Svalbard and concurring footprints in local sea ice cover
Dahlke, Sandro, Hughes, Nicholas E., Wagner, Penelope M., Gerland, Sebastian, Wawrzyniak, Tomasz, Ivanov, Boris, Maturilli, Marion
Published in International journal of climatology (01.10.2020)
Published in International journal of climatology (01.10.2020)
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Journal Article
dCas9-based gene editing for cleavage-free genomic knock-in of long sequences
Wang, Chengkun, Qu, Yuanhao, Cheng, Jason K W, Hughes, Nicholas W, Zhang, Qianhe, Wang, Mengdi, Cong, Le
Published in Nature cell biology (01.02.2022)
Published in Nature cell biology (01.02.2022)
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Journal Article
Machine-learning-optimized Cas12a barcoding enables the recovery of single-cell lineages and transcriptional profiles
Hughes, Nicholas W., Qu, Yuanhao, Zhang, Jiaqi, Tang, Weijing, Pierce, Justin, Wang, Chengkun, Agrawal, Aditi, Morri, Maurizio, Neff, Norma, Winslow, Monte M., Wang, Mengdi, Cong, Le
Published in Molecular cell (18.08.2022)
Published in Molecular cell (18.08.2022)
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Journal Article
Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects
Wang, Chengkun, Cheng, Jason K W, Zhang, Qianhe, Hughes, Nicholas W, Xia, Qiong, Winslow, Monte M, Cong, Le
Published in Nucleic acids research (06.04.2021)
Published in Nucleic acids research (06.04.2021)
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Journal Article
Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth
Tang, Rui, Shuldiner, Emily G, Kelly, Marcus, Murray, Christopher W, Hebert, Jess D, Andrejka, Laura, Tsai, Min K, Hughes, Nicholas W, Parker, Mitchell I, Cai, Hongchen, Li, Yao-Cheng, Wahl, Geoffrey M, Dunbrack, Roland L, Jackson, Peter K, Petrov, Dmitri A, Winslow, Monte M
Published in Nature cell biology (01.01.2023)
Published in Nature cell biology (01.01.2023)
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Journal Article
Territories within groups: the dynamic competition of drift-feeding juvenile Chinook salmon in 3-dimensional space
Neuswanger, Jason R, Rosenberger, Amanda E, Wipfli, Mark S, Hughes, Nicholas F
Published in Canadian journal of fisheries and aquatic sciences (01.02.2023)
Published in Canadian journal of fisheries and aquatic sciences (01.02.2023)
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Journal Article
The impact of self-harm by young people on parents and families: a qualitative study
Ferrey, Anne E, Hughes, Nicholas D, Simkin, Sue, Locock, Louise, Stewart, Anne, Kapur, Navneet, Gunnell, David, Hawton, Keith
Published in BMJ open (01.01.2016)
Published in BMJ open (01.01.2016)
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Journal Article
Estimating Cortical Feature Maps with Dependent Gaussian Processes
Hughes, Nicholas J., Goodhill, Geoffrey J.
Published in IEEE transactions on pattern analysis and machine intelligence (01.10.2017)
Published in IEEE transactions on pattern analysis and machine intelligence (01.10.2017)
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Journal Article
Limitations of Neural Map Topography for Decoding Spatial Information
Avitan, Lilach, Pujic, Zac, Hughes, Nicholas J, Scott, Ethan K, Goodhill, Geoffrey J
Published in The Journal of neuroscience (11.05.2016)
Published in The Journal of neuroscience (11.05.2016)
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Journal Article
A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer
Cai, Hongchen, Chew, Su Kit, Li, Chuan, Tsai, Min K, Andrejka, Laura, Murray, Christopher W, Hughes, Nicholas W, Shuldiner, Emily G, Ashkin, Emily L, Tang, Rui, Hung, King L, Chen, Leo C, Lee, Shi Ya C, Yousefi, Maryam, Lin, Wen-Yang, Kunder, Christian A, Cong, Le, McFarland, Christopher D, Petrov, Dmitri A, Swanton, Charles, Winslow, Monte M
Published in Cancer discovery (01.07.2021)
Published in Cancer discovery (01.07.2021)
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Journal Article
Low productivity of Chinook salmon strongly correlates with high summer stream discharge in two Alaskan rivers in the Yukon drainage
Neuswanger, Jason R, Wipfli, Mark S, Evenson, Matthew J, Hughes, Nicholas F, Rosenberger, Amanda E
Published in Canadian journal of fisheries and aquatic sciences (01.08.2015)
Published in Canadian journal of fisheries and aquatic sciences (01.08.2015)
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Journal Article
Navigating an unfamiliar world: how parents of young people who self‐harm experience support and treatment
Stewart, Anne, Hughes, Nicholas D., Simkin, Sue, Locock, Louise, Ferrey, Anne, Kapur, Navneet, Gunnell, David, Hawton, Keith
Published in Child and adolescent mental health (01.05.2018)
Published in Child and adolescent mental health (01.05.2018)
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Journal Article