Continuous Flow-Enabled Synthesis of Bench-Stable Bicyclo[1.1.1]pentane Trifluoroborate Salts and Their Utilization in Metallaphotoredox Cross-Couplings
VanHeyst, Michael D, Qi, Ji, Roecker, Anthony J, Hughes, Jonathan M. E, Cheng, Lili, Zhao, Zheyu, Yin, Jingjun
Published in Organic letters (21.02.2020)
Published in Organic letters (21.02.2020)
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Journal Article
Strain-release 2-azaallyl anion addition/borylation of [1.1.1]propellane: synthesis and functionalization of benzylamine bicyclo[1.1.1]pentyl boronates
Shelp, Russell A, Ciro, Anthony, Pu, Youge, Merchant, Rohan R, Hughes, Jonathan M. E, Walsh, Patrick J
Published in Chemical science (Cambridge) (14.04.2021)
Published in Chemical science (Cambridge) (14.04.2021)
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Journal Article
Alkyl sulfinates as cross-coupling partners for programmable and stereospecific installation of C(sp(3)) bioisosteres
Zhou, Min, Tsien, Jet, Dykstra, Ryan, Hughes, Jonathan M. E., Peters, Byron K., Merchant, Rohan R., Gutierrez, Osvaldo, Qin, Tian
Published in Nature chemistry (01.04.2023)
Published in Nature chemistry (01.04.2023)
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Journal Article
Programmable late-stage functionalization of bridge-substituted bicyclo[1.1.1]pentane bis-boronates
Yang, Yangyang, Tsien, Jet, Dykstra, Ryan, Chen, Si-Jie, Wang, James B., Merchant, Rohan R., Hughes, Jonathan M. E., Peters, Byron K., Gutierrez, Osvaldo, Qin, Tian
Published in Nature chemistry (01.02.2024)
Published in Nature chemistry (01.02.2024)
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Journal Article
The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer
Quiroz, Ryan V, Reutershan, Michael H, Schneider, Sebastian E, Sloman, David, Lacey, Brian M, Swalm, Brooke M, Yeung, Charles S, Gibeau, Craig, Spellman, Daniel S, Rankic, Danica A, Chen, Dapeng, Witter, David, Linn, Doug, Munsell, Erik, Feng, Guo, Xu, Haiyan, Hughes, Jonathan M. E, Lim, Jongwon, Saurí, Josep, Geddes, Kristin, Wan, Murray, Mansueto, My Sam, Follmer, Nicole E, Fier, Patrick S, Siliphaivanh, Phieng, Daublain, Pierre, Palte, Rachel L, Hayes, Robert P, Lee, Sandra, Kawamura, Shuhei, Silverman, Steven, Sanyal, Sulagna, Henderson, Timothy J, Ye, Yingchun, Gao, Yuanwei, Nicholson, Benjamin, Machacek, Michelle R
Published in Journal of medicinal chemistry (08.04.2021)
Published in Journal of medicinal chemistry (08.04.2021)
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Journal Article
Practical and Modular Construction of C(sp(3))-Rich Alkyl Boron Compounds
Yang, Yangyang, Tsien, Jet, Ben David, Ayala, Hughes, Jonathan M. E., Merchant, Rohan R., Qin, Tian
Published in Journal of the American Chemical Society (13.01.2021)
Published in Journal of the American Chemical Society (13.01.2021)
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Journal Article
Uncanonical Semireduction of Quinolines and Isoquinolines via Regioselective HAT-Promoted Hydrosilylation
Hu, Chao, Vo, Cuong, Merchant, Rohan R., Chen, Si-Jie, Hughes, Jonathan M. E., Peters, Byron K., Qin, Tian
Published in Journal of the American Chemical Society (11.01.2023)
Published in Journal of the American Chemical Society (11.01.2023)
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Journal Article
Asymmetric Synthesis of Tertiary and Secondary Cyclopropyl Boronates via Cyclopropanation of Enantioenriched Alkenyl Boronic Esters
Gutiérrez-Bonet, Álvaro, Popov, Stasik, Emmert, Marion H., Hughes, Jonathan M. E., Nolting, Andrew F., Ruccolo, Serge, Wang, Yunyi
Published in Organic letters (20.05.2022)
Published in Organic letters (20.05.2022)
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Journal Article
Nickel-Catalyzed Reductive Arylation of Redox Active Esters for the Synthesis of α-Aryl Nitriles: Investigation of a Chlorosilane Additive
Michel, Nicholas W M, Gabbey, Alexis L, Edjoc, Racquel K, Fagbola, Emmanuel, Hughes, Jonathan M E, Campeau, Louis-Charles, Rousseaux, Sophie A L
Published in Journal of organic chemistry (10.01.2024)
Published in Journal of organic chemistry (10.01.2024)
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Journal Article
Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii : From Screening Impurity to In Vivo Efficacy
Skudlarek, Jason W., Cooke, Andrew J., Mitchell, Helen J., Babaoglu, Kerim, Shaw, Anthony W., Tong, Ling, Nomland, Ashley B., Labroli, Marc, Sha, Deyou, Mulhearn, James J., Wu, Chengwei, Li, Sarah W., Beshore, Douglas C., Hughes, Jonathan M. E., Jouffroy, Matthieu, Wang, Hao, Balibar, Carl J., Painter, Ronald E., Shen, Pamela, Lange, Henry S., Ishchenko, Andrii, Chen, Yun-Ting, Klein, Daniel J., Tracy, Rodger W., Miller, Randy R., Cabalu, Tamara D., Wu, Zhe, Leithead, Andrew, Scapin, Giovanna, Hruza, Alan W., Dzhekieva, Liudmila, Bukhtiyarova, Marina, Homsher, Michelle F., Xu, Min, Bahnck-Teets, Carolyn, McKenney, David, Buevich, Alexei V., Liu, Jian, Zhang, Li-Kang, Meng, Tao, Kelly, Terri, DiNunzio, Edward, Soisson, Stephen, Cheng, Robert K. Y., Hennig, Michael, Raheem, Izzat, Walker, Scott S.
Published in Journal of medicinal chemistry (12.09.2024)
Published in Journal of medicinal chemistry (12.09.2024)
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Journal Article
PRMT5 억제제
CANDITO DAVID A, QUIROZ RYAN, WITTER DAVID, HUANG CHUNHUI, SILIPHAIVANH PHIENG, HUGHES JONATHAN M. E, HENDERSON TIMOTHY J, YE YINGCHUN, SCHNEIDER SEBASTIAN, KAWAMURA SHUHEI, YEUNG CHARLES S, FIER PATRICK S, WAN MURRAY, REUTERSHAN MICHAEL H, RAHALI HOUCINE, SANYAL SULAGNA, GIBEAU CRAIG, PAPARIN JEAN LAURENT, SILVERMAN STEVEN M, MACHACEK MICHELLE, SLOMAN DAVID L
Year of Publication 27.04.2021
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Year of Publication 27.04.2021
Patent
A Concise Enantioselective Total Synthesis of (-)-VirosaineA
Hughes, Jonathan M E, Gleason, James L
Published in Angewandte Chemie International Edition (28.08.2017)
Published in Angewandte Chemie International Edition (28.08.2017)
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