Alendronate Mechanism of Action: Geranylgeraniol, an Intermediate in the Mevalonate Pathway, Prevents Inhibition of Osteoclast Formation, Bone Resorption, and Kinase Activation in vitro
Fisher, J. E., Rogers, M. J., Halasy, J. M., Luckman, S. P., Hughes, D. E., Masarachia, P. J., Wesolowski, G., Russell, R. G. G., Rodan, G. A., Reszka, A. A.
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.1999)
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Journal Article
Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain
Seong, E, Wainer, B H, Hughes, E D, Saunders, T L, Burmeister, M, Faundez, V
Published in Molecular biology of the cell (01.01.2005)
Published in Molecular biology of the cell (01.01.2005)
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Journal Article
Nitrogen‐Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post‐Translational Prenylation of GTP‐Binding Proteins, Including Ras
Luckman, Steven P., Hughes, David E., Coxon, Fraser P., Russell, R. Graham G., Rogers, Michael J.
Published in Journal of bone and mineral research (01.04.1998)
Published in Journal of bone and mineral research (01.04.1998)
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Journal Article
The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters
MAJUMDAR, A. S, HUGHES, D. E, LICHTSTEINER, S. P, WANG, Z, LEBKOWSKI, J. S, VASSEROT, A. P
Published in Gene therapy (01.04.2001)
Published in Gene therapy (01.04.2001)
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Journal Article
The Mechanism of the Reaction of the Tollens Reagent
Benet, William E, Lewis, Gabriella S, Yang, Louise Z, Hughes, Peter D E
Published in Journal of chemical research (01.12.2011)
Published in Journal of chemical research (01.12.2011)
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Journal Article
Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo
Hughes, D E, Wright, K R, Uy, H L, Sasaki, A, Yoneda, T, Roodman, G D, Mundy, G R, Boyce, B F
Published in Journal of bone and mineral research (01.10.1995)
Published in Journal of bone and mineral research (01.10.1995)
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Journal Article
Integrin expression in human bone
Hughes, D E, Salter, D M, Dedhar, S, Simpson, R
Published in Journal of bone and mineral research (01.05.1993)
Published in Journal of bone and mineral research (01.05.1993)
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Journal Article
Artificial intelligence using deep learning to predict the anatomical outcome of rhegmatogenous retinal detachment surgery: a pilot study
Fung, Timothy H. M., John, Neville C. R. A., Guillemaut, Jean-Yves, Yorston, David, Frohlich, David, Steel, David H. W., Williamson, Tom H.
Published in Graefe's archive for clinical and experimental ophthalmology (01.03.2023)
Published in Graefe's archive for clinical and experimental ophthalmology (01.03.2023)
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Journal Article
Recent advances in bone biology provide insight into the pathogenesis of bone diseases
BOYCE, B. F, HUGHES, D. E, WRIGHT, K. R, XING, L, DAI, A
Published in Laboratory investigation (01.02.1999)
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Published in Laboratory investigation (01.02.1999)
Journal Article
The Addition of Hydrogen Halides to the Carbonyl Group to give gem -halogenohydrins
McManus, Michael D, Skinner, James B B, Hughes, D E Peter
Published in Journal of chemical research (01.06.2011)
Published in Journal of chemical research (01.06.2011)
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Journal Article
The modulation of the expression of IL-6 and its receptor in human osteoblasts in vitro
Littlewood, A J, Russell, J, Harvey, G R, Hughes, D E, Russell, R G, Gowen, M
Published in Endocrinology (Philadelphia) (01.09.1991)
Published in Endocrinology (Philadelphia) (01.09.1991)
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Journal Article
Phenotype and Outcomes of Phakic Versus Pseudophakic Primary Rhegmatogenous Retinal Detachments: Cataract or Cataract Surgery Related?
Ferrara, Mariantonia, Mehta, Alex, Qureshi, Hamza, Avery, Peter, Yorston, David, Laidlaw, D. Alistair, Williamson, Tom H., Steel, David H.W., Casswell, A.G., Morris, Andrew H.C., Jalil, Assad, Babar, Atiq R., Goldsmith, Craig, Steel, David, Sanchez-Chicharro, Diego, Hughes, E.D., Herbert, E.N., Jenkins, Huw, Khan, Imran J., Ellis, John D., Smith, Jonathan, Balaggan, Kamaljit S., Cornish, Kurt Spiteri, Wakeley, Laura, Costen, Mark, Tarafdar, Sonali, Charles, Stephen J., Winder, Stephen, Cochrane, Timothy, Ivanova, Tsveta, Papastavrou, Vasileios T., Tanner, Vaughan, Yorston, David, Laidlaw, D. Alistair, Williamson, Tom
Published in American journal of ophthalmology (01.02.2021)
Published in American journal of ophthalmology (01.02.2021)
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Journal Article
The production of cephalosporin C by Acremonium chrysogenum is improved by the intracellular expression of a bacterial hemoglobin
DeModena, J.A. (Exogene Corporation, Monrovia, CA), Gutierrez, S, Velasco, J, Fernandez, F.J, Fachini, R.A, Galazzo, J.L, Hughes, D.E, Martin, J.F
Published in Bio/technology (New York, N.Y. 1983) (01.08.1993)
Published in Bio/technology (New York, N.Y. 1983) (01.08.1993)
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Journal Article
Map positions of 47 Arabidopsis sequences with sequence similarity to disease resistance genes
Botella, Miguel A., Coleman, Mark J., Hughes, Douglas E., Nishimura, Marc T., Jones, Jonathan D.G., Somerville, Shauna C.
Published in The Plant journal : for cell and molecular biology (01.11.1997)
Published in The Plant journal : for cell and molecular biology (01.11.1997)
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Journal Article
Automated microanalysis using magnetic beads with commercial capillary electrophoretic instrumentation
Rashkovetsky, Leonid G., Lyubarskaya, Yelena V., Foret, Frantisek, Hughes, Dallas E., Karger, Barry L.
Published in Journal of Chromatography A (26.09.1997)
Published in Journal of Chromatography A (26.09.1997)
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Journal Article
Conference Proceeding