Molecular pathology, developmental changes and synaptic dysfunction in (pre-) symptomatic human C9ORF72-ALS/FTD cerebral organoids
van der Geest, Astrid T, Jakobs, Channa E, Ljubikj, Tijana, Huffels, Christiaan F M, Cañizares Luna, Marta, Vieira de Sá, Renata, Adolfs, Youri, de Wit, Marina, Rutten, Daan H, Kaal, Marthe, Zwartkruis, Maria M, Carcolé, Mireia, Groen, Ewout J N, Hol, Elly M, Basak, Onur, Isaacs, Adrian M, Westeneng, Henk-Jan, van den Berg, Leonard H, Veldink, Jan H, Schlegel, Domino K, Pasterkamp, R Jeroen
Published in Acta neuropathologica communications (18.09.2024)
Published in Acta neuropathologica communications (18.09.2024)
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Journal Article
Aß Pathology and Neuron–Glia Interactions: A Synaptocentric View
Huffels, Christiaan F. M., Middeldorp, Jinte, Hol, Elly M.
Published in Neurochemical research (01.04.2023)
Published in Neurochemical research (01.04.2023)
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Journal Article
A neuronal mechanism underlying decision-making deficits during hyperdopaminergic states
Verharen, Jeroen P. H., de Jong, Johannes W., Roelofs, Theresia J. M., Huffels, Christiaan F. M., van Zessen, Ruud, Luijendijk, Mieneke C. M., Hamelink, Ralph, Willuhn, Ingo, den Ouden, Hanneke E. M., van der Plasse, Geoffrey, Adan, Roger A. H., Vanderschuren, Louk J. M. J.
Published in Nature communications (21.02.2018)
Published in Nature communications (21.02.2018)
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Journal Article
Amyloid‐β plaques affect astrocyte Kir4.1 protein expression but not function in the dentate gyrus of APP/PS1 mice
Huffels, Christiaan F. M., Osborn, Lana M., Hulshof, Lianne A., Kooijman, Lieneke, Henning, Lukas, Steinhäuser, Christian, Hol, Elly M.
Published in Glia (01.04.2022)
Published in Glia (01.04.2022)
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Journal Article
Calcium signaling in individual APP/PS1 mouse dentate gyrus astrocytes increases ex vivo with Aβ pathology and age without affecting astrocyte network activity
Huffels, Christiaan F. M., Osborn, Lana M., Cappaert, Natalie L. M., Hol, Elly M.
Published in Journal of neuroscience research (01.06.2022)
Published in Journal of neuroscience research (01.06.2022)
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Journal Article
Early amyloid‐induced changes in microglia gene expression in male APP/PS1 mice
Oshima, Takuya, Kater, Mandy S. J., Huffels, Christiaan F. M., Wesseling, Evelyn M., Middeldorp, Jinte, Hol, Elly M., Verheijen, Mark H. G., Smit, August B., Boddeke, Erik W. G. M., Eggen, Bart J. L.
Published in Journal of neuroscience research (01.03.2024)
Published in Journal of neuroscience research (01.03.2024)
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Journal Article
Mechanical alterations of the hippocampus in the APP/PS1 Alzheimer’s disease mouse model
Antonovaite, Nelda, Hulshof, Lianne A., Huffels, Christiaan F.M., Hol, Elly M., Wadman, Wytse J., Iannuzzi, Davide
Published in Journal of the mechanical behavior of biomedical materials (01.10.2021)
Published in Journal of the mechanical behavior of biomedical materials (01.10.2021)
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Journal Article
Cover Image, Volume 70, Issue 4
Huffels, Christiaan F. M., Osborn, Lana M., Hulshof, Lianne A., Kooijman, Lieneke, Henning, Lukas, Steinhäuser, Christian, Hol, Elly M.
Published in Glia (01.04.2022)
Published in Glia (01.04.2022)
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Journal Article
Prevention of microgliosis halts early memory loss in a mouse model of Alzheimer’s disease
Kater, Mandy S.J., Huffels, Christiaan F.M., Oshima, Takuya, Renckens, Niek S., Middeldorp, Jinte, Boddeke, Erik W.G.M., Smit, August B., Eggen, Bart J.L., Hol, Elly M., Verheijen, Mark H.G.
Published in Brain, behavior, and immunity (01.01.2023)
Published in Brain, behavior, and immunity (01.01.2023)
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Journal Article
A neuronal mechanism underlying decision-making deficits during hyperdopaminergic states
Verharen, Jeroen P H, De Jong, Johannes W, Roelofs, Theresia J M, Huffels, Christiaan F M, Ruud Van Zessen, Mieneke C M Luijendijk, Hamelink, Ralph, Willuhn, Ingo, Hanneke E M Den Ouden, Van Der Plasse, Geoffrey, Adan, Roger A H, Louk J M J Vanderschuren
Published in bioRxiv (31.10.2017)
Published in bioRxiv (31.10.2017)
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