Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver
Monetti, Mara, Levin, Malin C., Watt, Matthew J., Sajan, Mini P., Marmor, Stephen, Hubbard, Brian K., Stevens, Robert D., Bain, James R., Newgard, Christopher B., Farese, Robert V., Hevener, Andrea L., Farese, Robert V.
Published in Cell metabolism (01.07.2007)
Published in Cell metabolism (01.07.2007)
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Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin
Owens, 3rd, A Phillip, Passam, Freda H, Antoniak, Silvio, Marshall, Stephanie M, McDaniel, Allison L, Rudel, Lawrence, Williams, Julie C, Hubbard, Brian K, Dutton, Julie-Ann, Wang, Jianguo, Tobias, Peter S, Curtiss, Linda K, Daugherty, Alan, Kirchhofer, Daniel, Luyendyk, James P, Moriarty, Patrick M, Nagarajan, Shanmugam, Furie, Barbara C, Furie, Bruce, Johns, Douglas G, Temel, Ryan E, Mackman, Nigel
Published in The Journal of clinical investigation (01.02.2012)
Published in The Journal of clinical investigation (01.02.2012)
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Vancomycin Assembly: Nature's Way
Hubbard, Brian K., Walsh, Christopher T.
Published in Angewandte Chemie (International ed.) (17.02.2003)
Published in Angewandte Chemie (International ed.) (17.02.2003)
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Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters
Castro-Perez, Jose, Briand, François, Gagen, Karen, Wang, Sheng-Ping, Chen, Ying, McLaren, David G., Shah, Vinit, Vreeken, Rob J., Hankemeier, Thomas, Sulpice, Thierry, Roddy, Thomas P., Hubbard, Brian K., Johns, Douglas G.
Published in Journal of lipid research (01.11.2011)
Published in Journal of lipid research (01.11.2011)
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PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain
Liu, Mali, Wu, Guoxin, Baysarowich, Jennifer, Kavana, Michael, Addona, George H., Bierilo, Kathleen K., Mudgett, John S., Pavlovic, Guillaume, Sitlani, Ayesha, Renger, John J., Hubbard, Brian K., Fisher, Timothy S., Zerbinatti, Celina V.
Published in Journal of lipid research (01.09.2010)
Published in Journal of lipid research (01.09.2010)
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A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1
Clifton, Matthew C, Dranow, David M, Leed, Alison, Fulroth, Ben, Fairman, James W, Abendroth, Jan, Atkins, Kateri A, Wallace, Ellen, Fan, Dazhong, Xu, Guoping, Ni, Z J, Daniels, Doug, Van Drie, John, Wei, Guo, Burgin, Alex B, Golub, Todd R, Hubbard, Brian K, Serrano-Wu, Michael H
Published in PloS one (24.04.2015)
Published in PloS one (24.04.2015)
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siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids[S]
Tadin-Strapps, Marija, Peterson, Laurence B., Cumiskey, Anne-Marie, Rosa, Raymond L., Mendoza, Vivienne Halili, Castro-Perez, Jose, Puig, Oscar, Zhang, Liwen, Strapps, Walter R., Yendluri, Satyasri, Andrews, Lori, Pickering, Victoria, Rice, Julie, Luo, Lily, Chen, Zhu, Tep, Samnang, Ason, Brandon, Somers, Elizabeth Polizzi, Sachs, Alan B., Bartz, Steven R., Tian, Jenny, Chin, Jayne, Hubbard, Brian K., Wong, Kenny K., Mitnaul, Lyndon J.
Published in Journal of lipid research (01.06.2011)
Published in Journal of lipid research (01.06.2011)
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A rapid method for cross-species quantitation of apolipoproteins A1, B48 and B100 in plasma by ultra-performance liquid chromatography/tandem mass spectrometry
Lassman, Michael E., McLaughlin, Theresa M., Somers, Elizabeth P., Stefanni, Alice C., Chen, Zhu, Murphy, Beth Ann, Bierilo, Kathleen K., Flattery, Amy M., Wong, Kenneth K., Castro-Perez, Jose M., Hubbard, Brian K., Roddy, Thomas P.
Published in Rapid communications in mass spectrometry (30.01.2012)
Published in Rapid communications in mass spectrometry (30.01.2012)
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Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice[S]
Han, Seongah, Akiyama, Taro E., Previs, Stephen F., Herath, Kithsiri, Roddy, Thomas P., Jensen, Kristian K., Guan, Hong-Ping, Murphy, Beth A., McNamara, Lesley A., Shen, Xun, Strapps, Walter, Hubbard, Brian K., Pinto, Shirly, Li, Cai, Li, Jing
Published in Journal of lipid research (01.10.2013)
Published in Journal of lipid research (01.10.2013)
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In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS[S]
Castro-Perez, Jose, Previs, Stephen F., McLaren, David G., Shah, Vinit, Herath, Kithsiri, Bhat, Gowri, Johns, Douglas G., Wang, Sheng-Ping, Mitnaul, Lyndon, Jensen, Kristian, Vreeken, Robert, Hankemeier, Thomas, Roddy, Thomas P., Hubbard, Brian K.
Published in Journal of lipid research (01.01.2011)
Published in Journal of lipid research (01.01.2011)
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Measurement of Fractional Synthetic Rates of Multiple Protein Analytes by Triple Quadrupole Mass Spectrometry
LEE, Anita Y. H, YATES, Nathan A, XUEMEI ZHAO, SPARROW, Carl P, HUBBARD, Brian K, RADER, Daniel J, SITLANI, Ayesha, MILLAR, John S, HENDRICKSON, Ronald C, ICHETOVKIN, Marina, DEYANOVA, Ekaterina, SOUTHWICK, Katie, FISHER, Timothy S, WEIXUN WANG, LODERSTEDT, James, WALKER, Nykia, HAIHONG ZHOU
Published in Clinical chemistry (Baltimore, Md.) (01.03.2012)
Published in Clinical chemistry (Baltimore, Md.) (01.03.2012)
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Quantifying apoprotein synthesis in rodents: coupling LC-MS/MS analyses with the administration of labeled water
Zhou, Haihong, Li, Wenyu, Wang, Sheng-Ping, Mendoza, Vivienne, Rosa, Raymond, Hubert, James, Herath, Kithsiri, McLaughlin, Theresa, Rohm, Rory J., Lassman, Michael E., Wong, Kenny K., Johns, Douglas G., Previs, Stephen F., Hubbard, Brian K., Roddy, Thomas P.
Published in Journal of lipid research (01.06.2012)
Published in Journal of lipid research (01.06.2012)
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The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species
McLaren, David G., He, Timothy, Wang, Sheng-Ping, Mendoza, Vivienne, Rosa, Raymond, Gagen, Karen, Bhat, Gowri, Herath, Kithsiri, Miller, Paul L., Stribling, Sloan, Taggart, Andrew, Imbriglio, Jason, Liu, Jinqi, Chen, Dunlu, Pinto, Shirly, Balkovec, James M., DeVita, Robert J., Marsh, Donald J., Castro-Perez, Jose M., Strack, Alison, Johns, Douglas G., Previs, Stephen F., Hubbard, Brian K., Roddy, Thomas P.
Published in Journal of lipid research (01.06.2011)
Published in Journal of lipid research (01.06.2011)
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Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1)
Fang, Chao, D’Souza, Brendan, Thompson, Christopher F, Clifton, Matthew C, Fairman, James W, Fulroth, Ben, Leed, Alison, McCarren, Patrick, Wang, Lili, Wang, Yikai, Feau, Clementine, Kaushik, Virendar K, Palmer, Michelle, Wei, Guo, Golub, Todd R, Hubbard, Brian K, Serrano-Wu, Michael H
Published in ACS medicinal chemistry letters (11.12.2014)
Published in ACS medicinal chemistry letters (11.12.2014)
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Molecular Cloning and Sequence Analysis of the Complestatin Biosynthetic Gene Cluster
Chiu, H T, Hubbard, B K, Shah, A N, Eide, J, Fredenburg, R A, Walsh, C T, Khosla, C
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2001)
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Hepatic acyl-CoA:diacylglcyerol acyltransferase (DGAT) overexpression, diacylglycerol, and insulin sensitivity
Monetti, Mara, Levin, Malin C, Watt, Matthew J, Hubbard, Brian K, Newgard, Christopher, Farese, Sr, Robert V, Hevener, Andrea L, Farese, Jr, Robert V
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2011)
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Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes
Johnson, Eachan O, LaVerriere, Emily, Office, Emma, Stanley, Mary, Meyer, Elisabeth, Kawate, Tomohiko, Gomez, James E, Audette, Rebecca E, Bandyopadhyay, Nirmalya, Betancourt, Natalia, Delano, Kayla, Da Silva, Israel, Davis, Joshua, Gallo, Christina, Gardner, Michelle, Golas, Aaron J, Guinn, Kristine M, Kennedy, Sofia, Korn, Rebecca, McConnell, Jennifer A, Moss, Caitlin E, Murphy, Kenan C, Nietupski, Raymond M, Papavinasasundaram, Kadamba G, Pinkham, Jessica T, Pino, Paula A, Proulx, Megan K, Ruecker, Nadine, Song, Naomi, Thompson, Matthew, Trujillo, Carolina, Wakabayashi, Shoko, Wallach, Joshua B, Watson, Christopher, Ioerger, Thomas R, Lander, Eric S, Hubbard, Brian K, Serrano-Wu, Michael H, Ehrt, Sabine, Fitzgerald, Michael, Rubin, Eric J, Sassetti, Christopher M, Schnappinger, Dirk, Hung, Deborah T
Published in Nature (London) (01.07.2019)
Published in Nature (London) (01.07.2019)
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Glycopeptide Antibiotic Biosynthesis: Enzymatic Assembly of the Dedicated Amino Acid Monomer (S)-3,5-Dihydroxyphenylglycine
Chen, Huawei, Tseng, Claire C., Hubbard, Brian K., Walsh, Christopher T.
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2001)
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Journal Article
Deoxysugars in Glycopeptide Antibiotics: Enzymatic Synthesis of TDP-L-Epivancosamine in Chloroeremomycin Biosynthesis
Chen, Huawei, Thomas, Michael G., Hubbard, Brian K., Losey, Heather C., Walsh, Christopher T., Burkart, Michael D.
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2000)
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