An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors
Lin, Tony Eight, Yen, Dyan, HuangFu, Wei‐Chun, Wu, Yi‐Wen, Hsu, Jui‐Yi, Yen, Shih‐Chung, Sung, Tzu‐Ying, Hsieh, Jui‐Hua, Pan, Shiow‐Lin, Yang, Chia‐Ron, Huang, Wei‐Jan, Hsu, Kai‐Cheng
Published in Protein science (01.06.2024)
Published in Protein science (01.06.2024)
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Journal Article
ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells
Chan, Tze‐Sian, Cheng, Li‐Hsin, Hsu, Chung‐Chi, Yang, Pei‐Ming, Liao, Tai‐Yan, Hsieh, Hsiao‐Yen, Lin, Pei‐Chun, HuangFu, Wei‐Chun, Chuu, Chih‐Pin, Tsai, Kelvin K.
Published in Molecular oncology (01.03.2024)
Published in Molecular oncology (01.03.2024)
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Journal Article
The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR
Kao, Jo-Chi, HuangFu, Wei-Chun, Tsai, Tsung-Ting, Ho, Min-Ru, Jhan, Ming-Kai, Shen, Ting-Jing, Tseng, Po-Chun, Wang, Yung-Ting, Lin, Chiou-Feng
Published in PLoS neglected tropical diseases (01.08.2018)
Published in PLoS neglected tropical diseases (01.08.2018)
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Journal Article
Anti‐TNF‐α restricts dengue virus‐induced neuropathy
Jhan, Ming‐Kai, HuangFu, Wei‐Chun, Chen, Yi‐Fan, Kao, Jo‐Chi, Tsai, Tsung‐Ting, Ho, Min‐Ru, Shen, Ting‐Jing, Tseng, Po‐Chun, Wang, Yung‐Ting, Lin, Chiou‐Feng
Published in Journal of leukocyte biology (01.11.2018)
Published in Journal of leukocyte biology (01.11.2018)
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Journal Article
A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo
Wu, Yi-Wen, Chao, Min-Wu, Tu, Huang-Ju, Chen, Liang-Chieh, Hsu, Kai-Cheng, Liou, Jing-Ping, Yang, Chia-Ron, Yen, Shih-Chung, HuangFu, Wei-Chun, Pan, Shiow-Lin
Published in Oncogenesis (New York, NY) (13.05.2021)
Published in Oncogenesis (New York, NY) (13.05.2021)
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Journal Article
3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity
Lee, Hsueh-Yun, Lee, Jiann-Fong, Kumar, Sunil, Wu, Yi-Wen, HuangFu, Wei-Chun, Lai, Mei-Jung, Li, Yu-Hsuan, Huang, Hsiang-Ling, Kuo, Fei-Chiao, Hsiao, Che-Jen, Cheng, Chun-Chun, Yang, Chia-Ron, Liou, Jing-Ping
Published in European journal of medicinal chemistry (05.01.2017)
Published in European journal of medicinal chemistry (05.01.2017)
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Journal Article
Identification and analysis of a selective DYRK1A inhibitor
Lin, Tony Eight, Chao, Min-Wu, HuangFu, Wei-Chun, Tu, Huang-Ju, Peng, Zhao-Xiang, Su, Chih-Jou, Sung, Tzu-Ying, Hsieh, Jui-Hua, Lee, Cheng-Chung, Yang, Chia-Ron, Pan, Shiow-Lin, Hsu, Kai-Cheng
Published in Biomedicine & pharmacotherapy (01.02.2022)
Published in Biomedicine & pharmacotherapy (01.02.2022)
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Journal Article
A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors
Hsu, Kai-Cheng, HuangFu, Wei-Chun, Lin, Tony Eight, Chao, Min-Wu, Sung, Tzu-Ying, Chen, Yi-Ying, Pan, Shiow-Lin, Lee, Jih-Chin, Tzou, Shey-Cherng, Sun, Chung-Ming, Yang, Jinn-Moon
Published in Scientific reports (29.06.2020)
Published in Scientific reports (29.06.2020)
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Journal Article
Sterol O-Acyltransferase 2 Contributes to the Yolk Cholesterol Trafficking during Zebrafish Embryogenesis
Chang, Nai-Yun, Chan, Yen-Ju, Ding, Shih-Torng, Lee, Yen-Hua, HuangFu, Wei-Chun, Liu, I-Hsuan
Published in PloS one (09.12.2016)
Published in PloS one (09.12.2016)
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Journal Article
Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, Min-Wu, Lin, Tony Eight, HuangFu, Wei-Chun, Chang, Chao-Di, Tu, Huang-Ju, Chen, Liang-Chieh, Yen, Shih-Chung, Sung, Tzu-Ying, Huang, Wei-Jan, Yang, Chia-Ron, Pan, Shiow-Lin, Hsu, Kai-Cheng
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
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Journal Article
1,4-Naphthoquinones as inhibitors of Itch, a HECT domain-E3 ligase, and tumor growth suppressors in multiple myeloma
Liu, Yi-Min, HuangFu, Wei-Chun, Huang, Han-Li, Wu, Wei-Cheng, Chen, Yi-Lin, Yen, Yun, Huang, Hsiang-Ling, Nien, Chih-Ying, Lai, Mei-Jung, Pan, Shiow-Lin, Liou, Jing-Ping
Published in European journal of medicinal chemistry (10.11.2017)
Published in European journal of medicinal chemistry (10.11.2017)
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Journal Article
The single nucleotide variant at c.662A>G in human RRM2B is a loss‐of‐function mutation
Tseng, Yen‐Tzu, Li, Shang‐Wei, HuangFu, Wei‐Chun, Yen, Yun, Liu, I‐Hsuan
Published in Molecular genetics & genomic medicine (01.11.2020)
Published in Molecular genetics & genomic medicine (01.11.2020)
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Journal Article
A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions
Lin, Tony Eight, HuangFu, Wei-Chun, Chao, Min-Wu, Sung, Tzu-Ying, Chang, Chao-Di, Chen, Yi-Ying, Hsieh, Jui-Hua, Tu, Huang-Ju, Huang, Han-Li, Pan, Shiow-Lin, Hsu, Kai-Cheng
Published in Frontiers in pharmacology (04.12.2018)
Published in Frontiers in pharmacology (04.12.2018)
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Journal Article
Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains
Hsu, Kai-Cheng, Hung, Hui-Chen, HuangFu, Wei-Chun, Sung, Tzu-Ying, Eight Lin, Tony, Fang, Ming-Yu, Chen, I-Jung, Pathak, Nikhil, Hsu, John T.-A., Yang, Jinn-Moon
Published in Scientific reports (26.09.2017)
Published in Scientific reports (26.09.2017)
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Journal Article
Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Lin, Chao-Feng, Hsu, Kai-Cheng, HuangFu, Wei-Chun, Lin, Tony Eight, Huang, Han-Li, Pan, Shiow-Lin
Published in BMC pharmacology & toxicology (12.03.2020)
Published in BMC pharmacology & toxicology (12.03.2020)
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Journal Article
A Novel Dual HDAC6 and Tubulin Inhibitor, MPT0B451, Displays Anti-tumor Ability in Human Cancer Cells in Vitro and in Vivo
Wu, Yi-Wen, Hsu, Kai-Cheng, Lee, Hsueh-Yun, Huang, Tsui-Chin, Lin, Tony E, Chen, Yi-Ling, Sung, Ting-Yi, Liou, Jing-Ping, Hwang-Verslues, Wendy W, Pan, Shiow-Lin, HuangFu, Wei-Chun
Published in Frontiers in pharmacology (13.03.2018)
Published in Frontiers in pharmacology (13.03.2018)
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Journal Article
EGFL6 promotes colorectal cancer cell growth and mobility and the anti-cancer property of anti-EGFL6 antibody
Sung, Ting-Yi, Huang, Han-Li, Cheng, Chun-Chun, Chang, Fu-Ling, Wei, Po-Li, Cheng, Ya-Wen, Huang, Cheng-Chiao, Lee, Yu-Ching, HuangFu, Wei-Chun, Pan, Shiow-Lin
Published in Cell & bioscience (16.03.2021)
Published in Cell & bioscience (16.03.2021)
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Journal Article
Pathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1
Qian, Juan, Zheng, Hui, Huangfu, Wei-Chun, Liu, Jianghuai, Carbone, Christopher J, Leu, N Adrian, Baker, Darren P, Fuchs, Serge Y
Published in PLoS pathogens (01.06.2011)
Published in PLoS pathogens (01.06.2011)
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