Regorafenib is effective against neuroblastoma in vitro and in vivo and inhibits the RAS/MAPK, PI3K/Akt/mTOR and Fos/Jun pathways
Subramonian, Divya, Phanhthilath, Nikki, Rinehardt, Hannah, Flynn, Sean, Huo, Yuchen, Zhang, Jing, Messer, Karen, Mo, Qianxing, Huang, Shixia, Lesperance, Jacqueline, Zage, Peter E.
Published in British journal of cancer (18.08.2020)
Published in British journal of cancer (18.08.2020)
Get full text
Journal Article
CCR2 Chemokine Receptors Enhance Growth and Cell-Cycle Progression of Breast Cancer Cells through SRC and PKC Activation
Yao, Min, Fang, Wei, Smart, Curtis, Hu, Qingting, Huang, Shixia, Alvarez, Nehemiah, Fields, Patrick, Cheng, Nikki
Published in Molecular cancer research (01.02.2019)
Published in Molecular cancer research (01.02.2019)
Get full text
Journal Article
TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis
Singh, Ramesh, Karri, Dileep, Shen, Hong, Shao, Jiangyong, Dasgupta, Subhamoy, Huang, Shixia, Edwards, Dean P, Ittmann, Michael M, O'Malley, Bert W, Yi, Ping
Published in The Journal of clinical investigation (01.07.2018)
Published in The Journal of clinical investigation (01.07.2018)
Get full text
Journal Article
Tamoxifen Resistance in Breast Tumors Is Driven by Growth Factor Receptor Signaling with Repression of Classic Estrogen Receptor Genomic Function
MASSARWEH, Suleiman, OSBORNE, C. Kent, CREIGHTON, Chad J, LANFANG QIN, TSIMELZON, Anna, SHIXIA HUANG, WEISS, Heidi, RIMAWI, Mothaffar, SCHIFF, Rachel
Published in Cancer research (Chicago, Ill.) (01.02.2008)
Published in Cancer research (Chicago, Ill.) (01.02.2008)
Get full text
Journal Article
Generation of an in vitro 3D PDAC stroma rich spheroid model
Ware, Matthew J, Keshishian, Vazrik, Law, Justin J, Ho, Jason C, Favela, Carlos A, Rees, Paul, Smith, Billie, Mohammad, Sayeeduddin, Hwang, Rosa F, Rajapakshe, Kimal, Coarfa, Cristian, Huang, Shixia, Edwards, Dean P, Corr, Stuart J, Godin, Biana, Curley, Steven A
Published in Biomaterials (01.11.2016)
Published in Biomaterials (01.11.2016)
Get full text
Journal Article
Metformin and an insulin/IGF-1 receptor inhibitor are synergistic in blocking growth of triple-negative breast cancer
Xue, Lei, Chen, Fengju, Yue, Fei, Camacho, Laura, Kothapalli, Sushma, Wei, Guanyun, Huang, Shixia, Mo, Qianxing, Ma, Fei, Li, Yi, Jiralerspong, Sao
Published in Breast cancer research and treatment (2021)
Published in Breast cancer research and treatment (2021)
Get full text
Journal Article
Targeting TGF-β for treatment of osteogenesis imperfecta
Song, I-Wen, Nagamani, Sandesh Cs, Nguyen, Dianne, Grafe, Ingo, Sutton, Vernon Reid, Gannon, Francis H, Munivez, Elda, Jiang, Ming-Ming, Tran, Alyssa, Wallace, Maegen, Esposito, Paul, Musaad, Salma, Strudthoff, Elizabeth, McGuire, Sharon, Thornton, Michele, Shenava, Vinitha, Rosenfeld, Scott, Huang, Shixia, Shypailo, Roman, Orwoll, Eric, Lee, Brendan
Published in The Journal of clinical investigation (01.04.2022)
Published in The Journal of clinical investigation (01.04.2022)
Get full text
Journal Article
miR‐130b directly targets ARHGAP1 to drive activation of a metastatic CDC42‐PAK1‐AP1 positive feedback loop in Ewing sarcoma
Satterfield, Laura, Shuck, Ryan, Kurenbekova, Lyazat, Allen‐Rhoades, Wendy, Edwards, Dean, Huang, Shixia, Rajapakshe, Kimal, Coarfa, Cristian, Donehower, Lawrence A., Yustein, Jason T.
Published in International journal of cancer (15.11.2017)
Published in International journal of cancer (15.11.2017)
Get full text
Journal Article
Estimation of leaf color variances of Cotinus coggygria based on geographic and environmental variables
Tan, Xing, Wu, Jiaojiao, Liu, Yun, Huang, Shixia, Gao, Lan, Zhang, Wen
Published in Journal of forestry research (01.04.2021)
Published in Journal of forestry research (01.04.2021)
Get full text
Journal Article
Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers
Kim, Jin-Ah, Tan, Ying, Wang, Xian, Cao, Xixi, Veeraraghavan, Jamunarani, Liang, Yulong, Edwards, Dean P., Huang, Shixia, Pan, Xuewen, Li, Kaiyi, Schiff, Rachel, Wang, Xiao-Song
Published in Nature communications (03.10.2016)
Published in Nature communications (03.10.2016)
Get full text
Journal Article
Insulin-Like Growth Factor-I Activates Gene Transcription Programs Strongly Associated With Poor Breast Cancer Prognosis
Creighton, Chad J, Casa, Angelo, Lazard, ZaWaunyka, Huang, Shixia, Tsimelzon, Anna, Hilsenbeck, Susan G, Osborne, Charles Kent, Lee, Adrian V
Published in Journal of clinical oncology (01.09.2008)
Published in Journal of clinical oncology (01.09.2008)
Get full text
Journal Article
SOD1 is a synthetic-lethal target in PPM1D -mutant leukemia cells
Zhang, Linda, Hsu, Joanne I, Braekeleer, Etienne D, Chen, Chun-Wei, Patel, Tajhal D, Martell, Alejandra G, Guzman, Anna G, Wohlan, Katharina, Waldvogel, Sarah M, Uryu, Hidetaka, Tovy, Ayala, Callen, Elsa, Murdaugh, Rebecca L, Richard, Rosemary, Jansen, Sandra, Vissers, Lisenka, de Vries, Bert B A, Nussenzweig, Andre, Huang, Shixia, Coarfa, Cristian, Anastas, Jamie, Takahashi, Koichi, Vassiliou, George, Goodell, Margaret A
Published in eLife (18.06.2024)
Published in eLife (18.06.2024)
Get full text
Journal Article
Mass Spectrometry-Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers
Mundt, Filip, Rajput, Sandeep, Li, Shunqiang, Ruggles, Kelly V, Mooradian, Arshag D, Mertins, Philipp, Gillette, Michael A, Krug, Karsten, Guo, Zhanfang, Hoog, Jeremy, Erdmann-Gilmore, Petra, Primeau, Tina, Huang, Shixia, Edwards, Dean P, Wang, Xiaowei, Wang, Xuya, Kawaler, Emily, Mani, D R, Clauser, Karl R, Gao, Feng, Luo, Jingqin, Davies, Sherri R, Johnson, Gary L, Huang, Kuan-Lin, Yoon, Christopher J, Ding, Li, Fenyö, David, Ellis, Matthew J, Townsend, R Reid, Held, Jason M, Carr, Steven A, Ma, Cynthia X
Published in Cancer research (Chicago, Ill.) (15.05.2018)
Published in Cancer research (Chicago, Ill.) (15.05.2018)
Get full text
Journal Article
Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage
Chang, Chi-Hsuan, Zhang, Mei, Rajapakshe, Kimal, Coarfa, Cristian, Edwards, Dean, Huang, Shixia, Rosen, Jeffrey M.
Published in Stem cell reports (08.09.2015)
Published in Stem cell reports (08.09.2015)
Get full text
Journal Article
CGRRF1, a growth suppressor, regulates EGFR ubiquitination in breast cancer
Lee, Yu-Ju, Ho, Shiuh-Rong, Graves, Joshua D, Xiao, Yang, Huang, Shixia, Lin, Weei-Chin
Published in Breast cancer research : BCR (04.12.2019)
Published in Breast cancer research : BCR (04.12.2019)
Get full text
Journal Article
Loss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer
Haricharan, Svasti, Punturi, Nindo, Singh, Purba, Holloway, Kimberly R, Anurag, Meenakshi, Schmelz, Jacob, Schmidt, Cheryl, Lei, Jonathan T, Suman, Vera, Hunt, Kelly, Olson, Jr, John A, Hoog, Jeremy, Li, Shunqiang, Huang, Shixia, Edwards, Dean P, Kavuri, Shyam M, Bainbridge, Matthew N, Ma, Cynthia X, Ellis, Matthew J
Published in Cancer discovery (01.10.2017)
Published in Cancer discovery (01.10.2017)
Get full text
Journal Article
TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy
Jayaraman, Padmini, Parikh, Falguni, Newton, Jared M., Hanoteau, Aurelie, Rivas, Charlotte, Krupar, Rosemarie, Rajapakshe, Kimal, Pathak, Ravi, Kanthaswamy, Kavin, MacLaren, Cassie, Huang, Shixia, Coarfa, Cristian, Spanos, Chad, Edwards, Dean P., Parihar, Robin, Sikora, Andrew G.
Published in Oncoimmunology (03.10.2018)
Published in Oncoimmunology (03.10.2018)
Get full text
Journal Article
Dimethyl Sulfoxide Inhibits Bile Acid Synthesis in Healthy Mice but Does Not Protect Mice from Bile-Acid-Induced Liver Damage
Chen, Xi, Li, Huiqiao, Liu, Yu'e, Qi, Jing, Dong, Bingning, Huang, Shixia, Zhao, Shangang, Zhu, Yi
Published in Biology (Basel, Switzerland) (01.08.2023)
Published in Biology (Basel, Switzerland) (01.08.2023)
Get full text
Journal Article
Regulation of OsmiR156h through Alternative Polyadenylation Improves Grain Yield in Rice
Zhao, Meng, Liu, Binmei, Wu, Kun, Ye, Yafeng, Huang, Shixia, Wang, Shuansuo, Wang, Yi, Han, Ruixi, Liu, Qian, Fu, Xiangdong, Wu, Yuejin
Published in PloS one (08.05.2015)
Published in PloS one (08.05.2015)
Get full text
Journal Article
Development of Resistance to Targeted Therapies Transforms the Clinically Associated Molecular Profile Subtype of Breast Tumor Xenografts
CREIGHTON, Chad J, MASSARWEH, Suleiman, SHIXIA HUANG, TSIMELZON, Anna, HILSENBECK, Susan G, OSBOME, C. Kent, JIANG SHOU, MALOMI, Luca, SCHIFF, Rachel
Published in Cancer research (Chicago, Ill.) (15.09.2008)
Published in Cancer research (Chicago, Ill.) (15.09.2008)
Get full text
Journal Article