Nanoscopic Insights of Amphiphilic Peptide against the Oligomer Assembly Process to Treat Huntington's Disease
He, Ruei‐Yu, Lai, Xiang‐Me, Sun, Chia‐Sui, Kung, Te‐Shien, Hong, Jhu‐Ying, Jheng, Yu‐Song, Liao, Wei‐Neng, Chen, Jen‐Kun, Liao, Yung‐Feng, Tu, Pang‐Hsien, Huang, Joseph Jen‐Tse
Published in Advanced science (01.01.2020)
Published in Advanced science (01.01.2020)
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Nanoscopic investigation of C9orf72 poly-GA oligomers on nuclear membrane disruption by a photoinducible platform
Chien, Hung-Ming, He, Ruei-Yu, Lee, Chi-Chang, Huang, Yung-An, Hung, I-Ju, Hou, Kai-Ting, Hsiao, Jye-Chian, Lu, Po-Chao, Agnihotri, Diksha, Hwang, Eric, Huang, Joseph Jen-Tse
Published in Communications chemistry (23.07.2021)
Published in Communications chemistry (23.07.2021)
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Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera
Tseng, Yu-Ling, Lu, Po-Chao, Lee, Chi-Chang, He, Ruei-Yu, Huang, Yung-An, Tseng, Yin-Chen, Cheng, Ting-Jen Rachel, Huang, Joseph Jen-Tse, Fang, Jim-Min
Published in Journal of biomedical science (26.04.2023)
Published in Journal of biomedical science (26.04.2023)
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Journal Article
Inhibition of TDP-43 aggregation by nucleic acid binding
Huang, Yi-Chen, Lin, Ku-Feng, He, Ruei-Yu, Tu, Pang-Hsien, Koubek, Jiri, Hsu, Yin-Chih, Huang, Joseph Jen-Tse
Published in PloS one (30.05.2013)
Published in PloS one (30.05.2013)
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The N-terminus of TDP-43 promotes its oligomerization and enhances DNA binding affinity
Chang, Chung-ke, Wu, Tzong-Huah, Wu, Chu-Ya, Chiang, Ming-hui, Toh, Elsie Khai-Woon, Hsu, Yin-Chih, Lin, Ku-Feng, Liao, Yu-heng, Huang, Tai-huang, Huang, Joseph Jen-Tse
Published in Biochemical and biophysical research communications (24.08.2012)
Published in Biochemical and biophysical research communications (24.08.2012)
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The influence of pathological mutations and proline substitutions in TDP-43 glycine-rich peptides on its amyloid properties and cellular toxicity
Sun, Chia-Sui, Wang, Cindy Yu-Hsiang, Chen, Bryan Po-Wen, He, Ruei-Yu, Liu, Gerard Chun-Hao, Wang, Chih-Hsien, Chen, Wenlung, Chern, Yijuang, Huang, Joseph Jen-Tse
Published in PloS one (04.08.2014)
Published in PloS one (04.08.2014)
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Conformational switch of polyglutamine-expanded huntingtin into benign aggregates leads to neuroprotective effect
Sun, Chia-Sui, Lee, Chi-Chang, Li, Yi-Ni, Yao-Chen Yang, Sunny, Lin, Chih-Hsiang, Chang, Yi-Che, Liu, Po-Fan, He, Ruei-Yu, Wang, Chih-Hsien, Chen, Wenlung, Chern, Yijuang, Jen-Tse Huang, Joseph
Published in Scientific reports (09.10.2015)
Published in Scientific reports (09.10.2015)
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Journal Article
Author Correction: Engineered droplet-forming peptide as photocontrollable phase modulator for fused in sarcoma protein
Chuang, Hao-Yu, He, Ruei-Yu, Huang, Yung-An, Hsu, Wan-Ting, Cheng, Ya-Jen, Guo, Zheng-Rong, Wali, Niaz, Hwang, Ing-Shouh, Shie, Jiun-Jie, Huang, Joseph Jen-Tse
Published in Nature communications (22.08.2024)
Published in Nature communications (22.08.2024)
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Journal Article
Engineered droplet-forming peptide as photocontrollable phase modulator for fused in sarcoma protein
Chuang, Hao-Yu, He, Ruei-Yu, Huang, Yung-An, Hsu, Wan-Ting, Cheng, Ya-Jen, Guo, Zheng-Rong, Wali, Niaz, Hwang, Ing-Shouh, Shie, Jiun-Jie, Huang, Joseph Jen-Tse
Published in Nature communications (06.07.2024)
Published in Nature communications (06.07.2024)
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Journal Article
Photochemical Activities of N-Nitroso Carboxamides and Sulfoximides and Their Application to DNA Cleavage
Hwu, Jih Ru, Huang, Joseph Jen-Tse, Tsai, Fu-Yuan, Tsay, Shwu-Chen, Hsu, Ming-Hua, Hwang, Kuo Chu, Horng, Jia-Cherng, Ho, Ja-an Annie, Lin, Chun-Cheng
Published in Chemistry : a European journal (07.09.2009)
Published in Chemistry : a European journal (07.09.2009)
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Journal Article
Polyglutamine-Specific Gold Nanoparticle Complex Alleviates Mutant Huntingtin-Induced Toxicity
Wahyuningtyas, Devi, Chen, Wen-Hao, He, Ruei-Yu, Huang, Yung-An, Tsao, Chia-Kang, He, Yu-Jung, Yu, Chu-Yi, Lu, Po-Chao, Chen, Yu-Cai, Wang, Sheng-Hann, Ng, Ka Chon, Po-Wen Chen, Bryan, Wei, Pei-Kuen, Shie, Jiun-Jie, Kuo, Chun-Hong, Sun, Y. Henry, Jen-Tse Huang, Joseph
Published in ACS applied materials & interfaces (29.12.2021)
Published in ACS applied materials & interfaces (29.12.2021)
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Study of Binding Interaction between Pif80 Protein Fragment and Aragonite
Du, Yuan-Peng, Chang, Hsun-Hui, Yang, Sheng-Yu, Huang, Shing-Jong, Tsai, Yu-Ju, Huang, Joseph Jen-Tse, Chan, Jerry Chun Chung
Published in Scientific reports (03.08.2016)
Published in Scientific reports (03.08.2016)
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Photocontrollable Probe Spatiotemporally Induces Neurotoxic Fibrillar Aggregates and Impairs Nucleocytoplasmic Trafficking
He, Ruei-Yu, Chao, Shu-Han, Tsai, Yu-Ju, Lee, Chi-Chang, Yu, Chu-Yi, Gao, Hua-De, Huang, Yung-An, Hwang, Eric, Lee, Hsien-Ming, Huang, Joseph Jen-Tse
Published in ACS nano (25.07.2017)
Published in ACS nano (25.07.2017)
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Journal Article
Delineating the membrane-disrupting and seeding properties of the TDP-43 amyloidogenic core
Liu, Gerard Chun-Hao, Chen, Bryan Po-Wen, Ye, Nancy Ting-Juan, Wang, Chih-Hsien, Chen, Wenlung, Lee, Hsien-Ming, Chan, Sunney I., Huang, Joseph Jen-Tse
Published in Chemical communications (Cambridge, England) (11.12.2013)
Published in Chemical communications (Cambridge, England) (11.12.2013)
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