The Role of the Antioxidant Response in Mitochondrial Dysfunction in Degenerative Diseases: Cross-Talk between Antioxidant Defense, Autophagy, and Apoptosis
Sahni, Sumit, Bae, Dong-Hun, Kalinowski, Danuta S., Chiang, Shannon, Huang, Michael L.-H., Richardson, Des R.
Published in Oxidative medicine and cellular longevity (01.01.2019)
Published in Oxidative medicine and cellular longevity (01.01.2019)
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Journal Article
Roads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signaling
Paluncic, Jasmina, Kovacevic, Zaklina, Jansson, Patric J., Kalinowski, Danuta, Merlot, Angelika M., Huang, Michael L.-H., Lok, Hiu Chuen, Sahni, Sumit, Lane, Darius J.R., Richardson, Des R.
Published in Biochimica et biophysica acta (01.04.2016)
Published in Biochimica et biophysica acta (01.04.2016)
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Journal Article
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol
Richardson, Des R., Lane, Darius J. R., Becker, Frika M., Huang, Michael L.-H., Whitnall, Megan, Rahmanto, Yohan Suryo, Sheftel, Alex D., Ponka, Prem, Snyder, Solomon H.
Published in Proceedings of the National Academy of Sciences - PNAS (15.06.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (15.06.2010)
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Journal Article
Pharmacological targeting of mitochondria in cancer stem cells: An ancient organelle at the crossroad of novel anti-cancer therapies
Skoda, Jan, Borankova, Karolina, Jansson, Patric J., Huang, Michael L.-H., Veselska, Renata, Richardson, Des R.
Published in Pharmacological research (01.01.2019)
Published in Pharmacological research (01.01.2019)
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Journal Article
Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia
Whitnall, Megan, Rahmanto, Yohan Suryo, Huang, Michael L.-H, Saletta, Federica, Lok, Hiu Chuen, Gutiérrez, Lucía, Lázaro, Francisco J, Fleming, Adam J, St. Pierre, Tim G, Mikhael, Marc R, Ponka, Prem, Richardson, Des R
Published in Proceedings of the National Academy of Sciences - PNAS (11.12.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (11.12.2012)
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Journal Article
Copper and conquer: copper complexes of di-2-pyridylketone thiosemicarbazones as novel anti-cancer therapeutics
Park, Kyung Chan, Fouani, Leyla, Jansson, Patric J, Wooi, Danson, Sahni, Sumit, Lane, Darius J R, Palanimuthu, Duraippandi, Lok, Hiu Chuen, Kovačević, Zaklina, Huang, Michael L H, Kalinowski, Danuta S, Richardson, Des R
Published in Metallomics (01.09.2016)
Published in Metallomics (01.09.2016)
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Journal Article
Exploiting Cancer Metal Metabolism using Anti-Cancer Metal- Binding Agents
Merlot, Angelica M, Kalinowski, Danuta S, Kovacevic, Zaklina, Jansson, Patric J, Sahni, Sumit, Huang, Michael L-H, Lane, Darius J R, Lok, Hiu, Richardson, Des R
Published in Current medicinal chemistry (01.01.2019)
Published in Current medicinal chemistry (01.01.2019)
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Journal Article
Mechanisms of impaired mitochondrial homeostasis and NAD+ metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation
Chiang, Shannon, Braidy, Nady, Maleki, Sanaz, Lal, Sean, Richardson, Des R., Huang, Michael L.-H.
Published in Redox biology (01.10.2021)
Published in Redox biology (01.10.2021)
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Journal Article
Frataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxia
Chiang, Shannon, Kovacevic, Zaklina, Sahni, Sumit, Lane, Darius J R, Merlot, Angelica M, Kalinowski, Danuta S, Huang, Michael L-H, Richardson, Des R
Published in Clinical science (1979) (01.06.2016)
Published in Clinical science (1979) (01.06.2016)
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Journal Article
The role of NDRG1 in the pathology and potential treatment of human cancers
Bae, Dong-Hun, Jansson, Patric J, Huang, Michael L, Kovacevic, Zaklina, Kalinowski, Danuta, Lee, C Soon, Sahni, Sumit, Richardson, Des R
Published in Journal of Clinical Pathology (01.11.2013)
Published in Journal of Clinical Pathology (01.11.2013)
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Journal Article
Book Review
Novel multifunctional iron chelators of the aroyl nicotinoyl hydrazone class that markedly enhance cellular NAD+/NADH ratios
Wu, Zhixuan, Palanimuthu, Duraippandi, Braidy, Nady, Salikin, Nor Hawani, Egan, Suhelen, Huang, Michael L.H., Richardson, Des R.
Published in British journal of pharmacology (01.05.2020)
Published in British journal of pharmacology (01.05.2020)
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Journal Article
Potent antimycobacterial activity of the pyridoxal isonicotinoyl hydrazone analog 2-pyridylcarboxaldehyde isonicotinoyl hydrazone: a lipophilic transport vehicle for isonicotinic acid hydrazide
Ellis, Samantha, Kalinowski, Danuta S, Leotta, Lisa, Huang, Michael L H, Jelfs, Peter, Sintchenko, Vitali, Richardson, Des R, Triccas, James A
Published in Molecular pharmacology (01.02.2014)
Published in Molecular pharmacology (01.02.2014)
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Journal Article
The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targets
Liu, Wensheng, Kovacevic, Zaklina, Peng, Zhihai, Jin, Runsen, Wang, Puxiongzhi, Yue, Fei, Zheng, Minhua, Huang, Michael L-H, Jansson, Patric J, Richardson, Vera, Kalinowski, Danuta S, Lane, Darius J R, Merlot, Angelica M, Sahni, Sumit, Richardson, Des R
Published in Oncotarget (03.11.2015)
Published in Oncotarget (03.11.2015)
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Journal Article
The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich’s ataxia
Richardson, Des R., Huang, Michael L-H., Whitnall, Megan, Becker, Erika M., Ponka, Prem, Suryo Rahmanto, Yohan
Published in Journal of molecular medicine (Berlin, Germany) (01.04.2010)
Published in Journal of molecular medicine (Berlin, Germany) (01.04.2010)
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Journal Article
The metastasis suppressor, NDRG1, attenuates oncogenic TGF-β and NF-κB signaling to enhance membrane E-cadherin expression in pancreatic cancer cells
Menezes, Sharleen V, Fouani, Leyla, Huang, Michael L H, Geleta, Bekesho, Maleki, Sanaz, Richardson, Alexander, Richardson, Des R, Kovacevic, Zaklina
Published in Carcinogenesis (New York) (06.07.2019)
Published in Carcinogenesis (New York) (06.07.2019)
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Journal Article
Letter to the Editor: "Analysis of the Interaction of Dp44mT with Human Serum Albumin and Calf Thymus DNA Using Molecular Docking and Spectroscopic Techniques"
Merlot, Angelica M, Sahni, Sumit, Lane, Darius J R, Richardson, Vera, Huang, Michael L H, Kalinowski, Danuta S, Richardson, Des R
Published in International journal of molecular sciences (16.11.2016)
Published in International journal of molecular sciences (16.11.2016)
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Journal Article
Molecular Alterations in a Mouse Cardiac Model of Friedreich Ataxia: An Impaired Nrf2 Response Mediated via Upregulation of Keap1 and Activation of the Gsk3β Axis
Anzovino, Amy, Chiang, Shannon, Brown, Bronwyn E, Hawkins, Clare L, Richardson, Des R, Huang, Michael L-H
Published in The American journal of pathology (01.12.2017)
Published in The American journal of pathology (01.12.2017)
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Journal Article
Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics
Kalinowski, Danuta S., Stefani, Christian, Toyokuni, Shinya, Ganz, Tomas, Anderson, Gregory J., Subramaniam, Nathan V., Trinder, Debbie, Olynyk, John K., Chua, Anita, Jansson, Patric J., Sahni, Sumit, Lane, Darius J.R., Merlot, Angelica M., Kovacevic, Zaklina, Huang, Michael L.H., Lee, C. Soon, Richardson, Des R.
Published in Biochimica et biophysica acta (01.04.2016)
Published in Biochimica et biophysica acta (01.04.2016)
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Journal Article
Mitochondrial DNA copy number in adults with and without Type 1 diabetes
Jenkins, Alicia J., Carroll, Luke M., Huang, Michael L.H., Wen-Loh, Yik, Mangani, Abubakar, O'Neal, David N., Januszewski, Andrzej S.
Published in Diabetes research and clinical practice (01.09.2023)
Published in Diabetes research and clinical practice (01.09.2023)
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Journal Article
Tumor stressors induce two mechanisms of intracellular P-glycoprotein–mediated resistance that are overcome by lysosomal-targeted thiosemicarbazones
Al-Akra, Lina, Bae, Dong-Hun, Sahni, Sumit, Huang, Michael L.H., Park, Kyung Chan, Lane, Darius J.R., Jansson, Patric J., Richardson, Des R.
Published in The Journal of biological chemistry (09.03.2018)
Published in The Journal of biological chemistry (09.03.2018)
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