Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma
Tai, Wei-Tien, Cheng, Ann-Lii, Shiau, Chung-Wai, Huang, Hsiang-Po, Huang, Jui-Wen, Chen, Pei-Jer, Chen, Kuen-Feng
Published in Journal of hepatology (01.11.2011)
Published in Journal of hepatology (01.11.2011)
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Protein tyrosine phosphatase 1B dephosphorylates PITX1 and regulates p120RasGAP in hepatocellular carcinoma
Tai, Wei‐Tien, Chen, Yao‐Li, Chu, Pei‐Yi, Chen, Li‐Ju, Hung, Man‐Hsin, Shiau, Chung‐Wai, Huang, Jui‐Wen, Tsai, Ming‐Hsien, Chen, Kuen‐Feng
Published in Hepatology (Baltimore, Md.) (01.05.2016)
Published in Hepatology (Baltimore, Md.) (01.05.2016)
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Discovery of novel src homology region 2 domain‐containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma
Tai, Wei‐Tien, Shiau, Chung‐Wai, Chen, Pei‐Jer, Chu, Pei‐Yi, Huang, Hsiang‐Po, Liu, Chun‐Yu, Huang, Jui‐Wen, Chen, Kuen‐Feng
Published in Hepatology (Baltimore, Md.) (01.01.2014)
Published in Hepatology (Baltimore, Md.) (01.01.2014)
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A novel AMPK activator shows therapeutic potential in hepatocellular carcinoma by suppressing HIF1α‐mediated aerobic glycolysis
Tseng, Hsing‐I, Zeng, Yi‐Siang, Lin, Ying‐Chung Jimmy, Huang, Jui‐Wen, Lin, Chih‐Lung, Lee, Meng‐Hsuan, Yang, Fan‐Wei, Fang, Te‐Ping, Mar, Ai‐Chung, Su, Jung‐Chen
Published in Molecular oncology (01.06.2022)
Published in Molecular oncology (01.06.2022)
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From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors
JIUXIANG ZHU, HUANG, Jui-Wen, TSENG, Ping-Hui, YANG, Ya-Ting, FOWBLE, Joseph, SHIAU, Chung-Wai, SHAW, Yeng-Jeng, KULP, Samuel K, CHEN, Ching-Shih
Published in Cancer research (Chicago, Ill.) (15.06.2004)
Published in Cancer research (Chicago, Ill.) (15.06.2004)
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SHP-1 is a target of regorafenib in colorectal cancer
Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Lin, Hang, Hung, Man-Hsin, Chen, Yen-Lin, Huang, Jui-Wen, Tai, Wei-Tien, Yu, Hui-Chuan, Chen, Kuen-Feng
Published in Oncotarget (15.08.2014)
Published in Oncotarget (15.08.2014)
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Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma
Teng, Hao-Wei, Hung, Man-Hsin, Chen, Li-Ju, Chang, Mao-Ju, Hsieh, Feng-Shu, Tsai, Ming-Hsien, Huang, Jui-Wen, Lin, Chih-Lung, Tseng, Hsiang-Wen, Kuo, Zong-Keng, Jiang, Jeng-Kai, Yang, Shung-Haur, Shiau, Chung-Wai, Chen, Kuen-Feng
Published in Scientific reports (18.10.2016)
Published in Scientific reports (18.10.2016)
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A porphodimethene chemical inhibitor of uroporphyrinogen decarboxylase
Yip, Kenneth W, Zhang, Zhan, Sakemura-Nakatsugawa, Noriko, Huang, Jui-Wen, Vu, Nhu Mai, Chiang, Yi-Kun, Lin, Chih-Lung, Kwan, Jennifer Y Y, Yue, Shijun, Jitkova, Yulia, To, Terence, Zahedi, Payam, Pai, Emil F, Schimmer, Aaron D, Lovell, Jonathan F, Sessler, Jonathan L, Liu, Fei-Fei
Published in PloS one (25.02.2014)
Published in PloS one (25.02.2014)
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Extended Dynamic Range imaging: A spatial down-sampling approach
Huei-Yung Lin, Jui-Wen Huang
Published in 2014 IEEE International Conference on Systems, Man, and Cybernetics (SMC) (01.10.2014)
Published in 2014 IEEE International Conference on Systems, Man, and Cybernetics (SMC) (01.10.2014)
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Conference Proceeding
Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity
Chen, Kuen-Feng, Tai, Wei-Tien, Hsu, Cheng-Yi, Huang, Jui-Wen, Liu, Chun-Yu, Chen, Pei-Jer, Kim, InKi, Shiau, Chung-Wai
Published in European journal of medicinal chemistry (01.09.2012)
Published in European journal of medicinal chemistry (01.09.2012)
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A Highly Selective Rho-Kinase Inhibitor (ITRI-E-212) Potentially Treats Glaucoma Upon Topical Administration With Low Incidence of Ocular Hyperemia
Hsu, Cherng-Ru, Chen, Yi-Hsun, Liu, Chih-Peng, Chen, Chih-Hung, Huang, Kuo-Kuei, Huang, Jui-Wen, Lin, Meng-Nan, Lin, Chih-Lung, Chen, Wan-Ru, Hsu, Yi-Ling, Lee, Tze-Chung, Chou, Shuen-Hsiang, Tu, Chia-Mu, Hwang, Chrong-Shiong, Huang, Yu Chuan, Lu, Da-Wen
Published in Investigative ophthalmology & visual science (01.02.2019)
Published in Investigative ophthalmology & visual science (01.02.2019)
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Journal Article
Editor's Note: From the Cyclooxygenase-2 Inhibitor Celecoxib to a Novel Class of 3-Phosphoinositide-Dependent Protein Kinase-1 Inhibitors
Zhu, Jiuxiang, Huang, Jui-Wen, Tseng, Ping-Hui, Yang, Ya-Ting, Fowble, Joseph, Shiau, Chung-Wai, Shaw, Yeng-Jeng, Kulp, Samuel K, Chen, Ching-Shih
Published in Cancer research (Chicago, Ill.) (01.04.2019)
Published in Cancer research (Chicago, Ill.) (01.04.2019)
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Nintedanib (BIBF-1120) inhibits hepatocellular carcinoma growth independent of angiokinase activity
Tai, Wei-Tien, Shiau, Chung-Wai, Li, Yong-Shi, Chang, Chun-Wei, Huang, Jui-Wen, Hsueh, Ting-Ting, Yu, Hui-Chuan, Chen, Kuen-Feng
Published in Journal of hepatology (01.07.2014)
Published in Journal of hepatology (01.07.2014)
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Binding Properties of the C-terminal Domain of VIAF
Bisson, William H, Zhang, Ziming, Welsh, Kate, Huang, Jui-Wen, Ryan, Jennifer, Reed, John C, Pellecchia, Maurizio
Published in Chemical biology & drug design (01.11.2008)
Published in Chemical biology & drug design (01.11.2008)
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Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARγ
SHIAU, Chung-Wai, YANG, Chih-Cheng, KULP, Samuel K, CHEN, Kuen-Feng, CHEN, Chang-Shi, HUANG, Jui-Wen, CHEN, Ching-Shih
Published in Cancer research (Chicago, Ill.) (15.02.2005)
Published in Cancer research (Chicago, Ill.) (15.02.2005)
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A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation
Chen, Kuen-Feng, Su, Jung-Chen, Liu, Chun-Yu, Huang, Jui-Wen, Chen, Kuei-Chiu, Chen, Wei-Lin, Tai, Wei-Tien, Shiau, Chung-Wai
Published in Cancer letters (01.08.2012)
Published in Cancer letters (01.08.2012)
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Screening Multicomponent Reactions for X-Linked Inhibitor of Apoptosis-Baculoviral Inhibitor of Apoptosis Protein Repeats Domain Binder
Monfardini, Ilaria, Huang, Jui-Wen, Beck, Barbara, Cellitti, Jason F, Pellecchia, Maurizio, Dömling, Alexander
Published in Journal of medicinal chemistry (10.02.2011)
Published in Journal of medicinal chemistry (10.02.2011)
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Development of erlotinib derivatives as CIP2A-ablating agents independent of EGFR activity
Chen, Kuen-Feng, Pao, Kuan-Chuan, Su, Jung-Chen, Chou, Yi-Chieh, Liu, Chun-Yu, Chen, Hui-Ju, Huang, Jui-Wen, Kim, InKi, Shiau, Chung-Wai
Published in Bioorganic & medicinal chemistry (15.10.2012)
Published in Bioorganic & medicinal chemistry (15.10.2012)
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Journal Article
RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells
Su, Jung-Chen, Chiang, Heng-Chieh, Tseng, Ping-Hui, Tai, Wei-Tien, Hsu, Cheng-Yi, Li, Yong-Shi, Huang, Jui-Wen, Ko, Ching-Huai, Lin, Mai-Wei, Chu, Pei-Yi, Liu, Chun-Yu, Chen, Kuen-Feng, Shiau, Chung-Wai
Published in Carcinogenesis (New York) (01.12.2014)
Published in Carcinogenesis (New York) (01.12.2014)
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Journal Article
RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells
Su, Jung-Chen, Tseng, Ping-Hui, Hsu, Cheng-Yi, Tai, Wei-Tien, Huang, Jui-Wen, Ko, Ching-Huai, Lin, Mai-Wei, Liu, Chun-Yu, Chen, Kuen-Feng, Shiau, Chung-Wai
Published in Oncotarget (15.07.2014)
Published in Oncotarget (15.07.2014)
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