Palladium-catalyzed dual C-H activation of N-phenyl-1H-indole-3-carboxamides for the synthesis of 5,11-dihydro-6H-indolo[3,2-c]quinolin-6-ones
Chen, Jiun-Hong, Huang, Jiann-Jyh, Wu, Ming-Jung
Published in Journal of the Chinese Chemical Society (Taipei) (01.12.2023)
Published in Journal of the Chinese Chemical Society (Taipei) (01.12.2023)
Get more information
Journal Article
Synthesis of Spirocyclopropane-Containing 4H-Pyrazolo[1,5-a]indoles via Alkylative Dearomatization and Intramolecular N-Imination of an Indole–O-(Methylsulfonyl)oxime
Huang, Jiann-Jyh, Liao, Hung-Chun, Hsu, Cheng-En, Liu, Yan-Ru, Chang, Yi-Fu, Chou, Shan-Yen
Published in Molecules (Basel, Switzerland) (31.08.2023)
Published in Molecules (Basel, Switzerland) (31.08.2023)
Get full text
Journal Article
Design, synthesis, and in vitro/vivo anticancer activity of 4‐substituted 7‐(3‐fluoro‐4‐methoxybenzyl)‐7H‐pyrrolo[2,3‐d]pyrimidines
Tsai, Pei‐Yi, Hu, Gong‐Siang, Huang, Po‐Hsun, Jheng, Huei‐Lin, Lan, Chi‐Hsuan, Chen, You‐Sin, Chang, Jia‐Ming, Chuang, Shih‐Hsien, Huang, Jiann‐Jyh
Published in Journal of the Chinese Chemical Society (Taipei) (01.09.2021)
Published in Journal of the Chinese Chemical Society (Taipei) (01.09.2021)
Get full text
Journal Article
The inhibition profiles of 4'‐acylpyrrole–5‐fluoroindolin‐2‐ones with a C‐3' side chain for VEGFR2, PDGFR‐β, and FGFR‐1 protein kinases
Huang, Jiann‐Jyh, Lin, Yu‐Hsiang, Lai, Chun‐Liang, Yang, Sheng‐Chuan, Lin, Shu Fu, Yang, Ju‐Ying, Huang, Hung‐Jyun, Liu, Chiawei, Wei, Win‐Yin, Chuang, Shih‐Hsien, Chiang, Chao‐Cheng, Lee, Ying‐Shuen E., Liao, Chu‐Bin, Chern, Ching Yuh
Published in Journal of the Chinese Chemical Society (Taipei) (01.03.2020)
Published in Journal of the Chinese Chemical Society (Taipei) (01.03.2020)
Get full text
Journal Article
Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1
Huang, Lynn Y L, Lee, Ying-Shuan, Huang, Jiann-Jyh, Chang, Chia-chi, Chang, Jia-Ming, Chuang, Shih-Hsien, Kao, Kuo-Jang, Tsai, Yung-Jen, Tsai, Pei-Yi, Liu, Chia-Wei, Lin, Her-Sheng, Lau, Johnson Y N
Published in Journal of experimental & clinical cancer research (09.01.2014)
Published in Journal of experimental & clinical cancer research (09.01.2014)
Get full text
Journal Article
Synthesis and antiproliferative evaluation of N,N-disubstituted-N′-[1-aryl-1H-pyrazol-5-yl]-methnimidamides
Cheng, Kaung-Min, Huang, Yu-Ying, Huang, Jiann-Jyh, Kaneko, Kimiyoshi, Kimura, Masayuki, Takayama, Hiroyuki, Juang, Shin-Hun, Wong, Fung Fuh
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Get full text
Journal Article
Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation
Tsai, Pei-Yi, Ka, Shuk-Man, Chang, Jia-Ming, Chen, Hsiang-Cheng, Shui, Hao-Ai, Li, Chen-Yun, Hua, Kuo-Feng, Chang, Wen-Liang, Huang, Jiann-Jyh, Yang, Sung-Sen, Chen, Ann
Published in Free radical biology & medicine (01.08.2011)
Published in Free radical biology & medicine (01.08.2011)
Get full text
Journal Article
Synthesis of 1,3,4-Oxadiazole-Based Aromatic and Heterocyclic/Phenylpyrazole Derivatives
Wang, Li-Ya, Chang, En-Chiuan, Yeh, Mou-Yung, Chung, Yu Hsuan, Huang, Jiann-Jyh, Wong, Fung Fuh
Published in Heteroatom chemistry (01.05.2014)
Published in Heteroatom chemistry (01.05.2014)
Get full text
Journal Article
Recovery of spent alumina-supported platinum catalyst and reduction of platinum oxide via plasma sintering technique
Chiang, Kuo-Chen, Chen, Kun-Lung, Chen, Chun-Yen, Huang, Jiann-Jyh, Shen, Yun-Hwei, Yeh, Mou-Yung, Wong, Fung Fuh
Published in Journal of the Taiwan Institute of Chemical Engineers (2011)
Published in Journal of the Taiwan Institute of Chemical Engineers (2011)
Get full text
Journal Article
Improvement of the thermal latency for epoxy-phenolic resins by novel amphiphatic imidazole catalysts
Wong, Fung Fuh, Lin, Chun Min, Chen, Kun-Lung, Shen, Yun-Hwei, Huang, Jiann-Jyh
Published in Macromolecular research (01.04.2010)
Published in Macromolecular research (01.04.2010)
Get full text
Journal Article
Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy
Chuang, Shih-Hsien, Lee, Ying-Shuan E., Huang, Lynn Y.L., Chen, Chi-Kuan, Lai, Chun-Liang, Lin, Yu-Hsiang, Yang, Ju-Ying, Yang, Sheng-Chuan, Chang, Lien-Hsiang, Chen, Ching-Hui, Liu, Chia-Wei, Lin, Her-Sheng, Lee, Yi-Ru, Huang, Kuan Pin, Fu, Kuo Chu, Jen, Hsueh-Min, Lai, Jun-Yu, Jian, Pei-Shiou, Wang, Yu-Chuan, Hsueh, Wen-Yun, Tsai, Pei-Yi, Hong, Wan-Hua, Chang, Chia-Chi, Wu, Diana ZC, Wu, Jinn, Chen, Meng-Hsin, Yu, Kuo-Ming, Chern, Ching Yuh, Chang, Jia-Ming, Lau, Johnson Y.N., Huang, Jiann-Jyh
Published in European journal of medicinal chemistry (01.04.2020)
Published in European journal of medicinal chemistry (01.04.2020)
Get full text
Journal Article
Design and synthesis of 4-anilinoquinazolines as Raf kinase inhibitors. Part 1. Selective B-Raf/B-Raf(V600E) and potent EGFR/VEGFR2 inhibitory 4-(3-hydroxyanilino)-6-(1H-1,2,3-triazol-4-yl)quinazolines
Lee, Cheng, Liao, Chu-Bin, Chen, Chih-Shang, Cheng, Fen-Ying, Chung, Yu-Hsuan, Wang, Yu-Chuan, Ciou, Sian-Yi, Hsueh, Wen-Yun, Lo, Tzu-Hao, Huang, Guan-Ru, Huang, Hsin-Yi, Tsai, Chia-Shen, Lu, Yu-Jung, Chuang, Shih-Hsien, Huang, Jiann-Jyh
Published in Bioorganic chemistry (01.04.2021)
Published in Bioorganic chemistry (01.04.2021)
Get full text
Journal Article
Copper(I)-Catalyzed Nitrile-Addition/ N -Arylation Ring-Closure Cascade: Synthesis of 5,11-Dihydro-6 H -indolo[3,2- c ]quinolin-6-ones as Potent Topoisomerase-I Inhibitors
Hsueh, Wen-Yun, Lee, Ying-Shuan E, Huang, Min-Sian, Lai, Chin-Hung, Gao, Yu-Sheng, Lin, Jo-Chu, Chen, Yu-Fen, Chang, Chih-Lin, Chou, Shan-Yen, Chen, Shyh-Fong, Lu, Yann-Yu, Chang, Lien-Hsiang, Lin, Shu Fu, Lin, Yu-Hsiang, Hsu, Pi-Chen, Wei, Win-Yin, Huang, Ya-Chi, Kao, Yi-Feng, Teng, Li-Wei, Liu, Hung-Huang, Chen, Ying-Chou, Yuan, Ta-Tung, Chan, Ya-Wen, Huang, Po-Hsun, Chao, Yu-Ting, Huang, Shin-Yi, Jian, Bo-Han, Huang, Hsin-Yi, Yang, Sheng-Chuan, Lo, Tzu-Hao, Huang, Guan-Ru, Wang, Shao-Yun, Lin, Her-Sheng, Chuang, Shih-Hsien, Huang, Jiann-Jyh
Published in Journal of medicinal chemistry (11.02.2021)
Published in Journal of medicinal chemistry (11.02.2021)
Get full text
Journal Article
Vilsmeier–Haack reagent-promoted formyloxylation of α-chloro-N-arylacetamides by formamide
Huang, Jiann-Jyh, Lu, Shi-Han, Chung, Yu Hsuan, Wong, Fung Fuh
Published in RSC advances (01.01.2015)
Published in RSC advances (01.01.2015)
Get full text
Journal Article
Discovery of 4‑Aryl‑N‑arylcarbonyl-2-aminothiazoles as Hec1/Nek2 Inhibitors. Part I: Optimization of in Vitro Potencies and Pharmacokinetic Properties
Lee, Ying-Shuan E, Chuang, Shih-Hsien, Huang, Lynn Y. L, Lai, Chun-Liang, Lin, Yu-Hsiang, Yang, Ju-Ying, Liu, Chia-Wei, Yang, Sheng-chuan, Lin, Her-Sheng, Chang, Chia-chi, Lai, Jun-Yu, Jian, Pei-Shiou, Lam, King, Chang, Jia-Ming, Lau, Johnson Y. N, Huang, Jiann-Jyh
Published in Journal of medicinal chemistry (22.05.2014)
Published in Journal of medicinal chemistry (22.05.2014)
Get full text
Journal Article
One-flask synthesis of 1,3,5-trisubstituted 1,2,4-triazoles from nitriles and hydrazonoyl chlorides via 1,3-dipolar cycloaddition
Wang, Li-Ya, Tsai, Henry J., Lin, Hui-Yi, Kaneko, Kimiyoshi, Cheng, Fen-Ying, Shih, Hsin-Siao, Wong, Fung Fuh, Huang, Jiann-Jyh
Published in RSC advances (2014)
Published in RSC advances (2014)
Get full text
Journal Article
Discovery of Pyrrole−Indoline-2-ones as Aurora Kinase Inhibitors with a Different Inhibition Profile
Chiang, Chao-Cheng, Lin, Yu-Hsiang, Lin, Shu Fu, Lai, Chun-Liang, Liu, Chiawei, Wei, Win-Yin, Yang, Sheng-chuan, Wang, Ru-Wen, Teng, Li-Wei, Chuang, Shih-Hsien, Chang, Jia-Ming, Yuan, Ta-Tung, Lee, Ying-Shuen, Chen, Paonien, Chi, Wei-Kuang, Yang, Ju-Ying, Huang, Hung-Jyun, Liao, Chu-Bin, Huang, Jiann-Jyh
Published in Journal of medicinal chemistry (26.08.2010)
Published in Journal of medicinal chemistry (26.08.2010)
Get full text
Journal Article
Activity of a novel Hec1-targeted anticancer compound against breast cancer cell lines in vitro and in vivo
Huang, Lynn Y L, Chang, Chia-Chi, Lee, Ying-Shuan, Chang, Jia-Ming, Huang, Jiann-Jyh, Chuang, Shih-Hsien, Kao, Kuo-Jang, Lau, Gillian M G, Tsai, Pei-Yi, Liu, Chia-Wei, Lin, Her-Sheng, Lau, Johnson Y N
Published in Molecular cancer therapeutics (01.06.2014)
Published in Molecular cancer therapeutics (01.06.2014)
Get full text
Journal Article