Observing inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution
Marx, Sinduja K, Mickolajczyk, Keith J, Craig, Jonathan M, Thomas, Christopher A, Pfeffer, Akira M, Abell, Sarah J, Carrasco, Jessica D, Franzi, Michaela C, Huang, Jesse R, Kim, Hwanhee C, Brinkerhoff, Henry, Kapoor, Tarun M, Gundlach, Jens H, Laszlo, Andrew H
Published in Nucleic acids research (22.09.2023)
Published in Nucleic acids research (22.09.2023)
Get full text
Journal Article
Elucidating the mechanism of PI3K when interacting with TRPV1
Huang, Jesse R., Swanson, Teresa M., Gordon, Moshe T., Gordon, Sharona E.
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
Get full text
Journal Article
Assessing Readability of an 8‑Letter Expanded Deoxyribonucleic Acid Alphabet with Nanopores
Thomas, Christopher A., Craig, Jonathan M., Hoshika, Shuichi, Brinkerhoff, Henry, Huang, Jesse R., Abell, Sarah J., Kim, Hwanhee C., Franzi, Michaela C., Carrasco, Jessica D., Kim, Hyo-Joong, Smith, Drew C., Gundlach, Jens H., Benner, Steven A., Laszlo, Andrew H.
Published in Journal of the American Chemical Society (10.04.2023)
Published in Journal of the American Chemical Society (10.04.2023)
Get full text
Journal Article
Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase
Nova, Ian C, Craig, Jonathan M, Mazumder, Abhishek, Laszlo, Andrew H, Derrington, Ian M, Noakes, Matthew T, Brinkerhoff, Henry, Yang, Shuya, Vahedian-Movahed, Hanif, Li, Lingting, Zhang, Yu, Bowman, Jasmine L, Huang, Jesse R, Mount, Jonathan W, Ebright, Richard H, Gundlach, Jens H
Published in Proceedings of the National Academy of Sciences - PNAS (16.07.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (16.07.2024)
Get full text
Journal Article
Nanopore tweezers measurements of RecQ conformational changes reveal the energy landscape of helicase motion
Craig, Jonathan M, Mills, Maria, Kim, Hwanhee C, Huang, Jesse R, Abell, Sarah J, Mount, Jonathan W, Gundlach, Jens H, Neuman, Keir C, Laszlo, Andrew H
Published in Nucleic acids research (14.10.2022)
Published in Nucleic acids research (14.10.2022)
Get full text
Journal Article
Nanopore Sequencing of an Expanded Genetic Alphabet Reveals High-Fidelity Replication of a Predominantly Hydrophobic Unnatural Base Pair
Ledbetter, Michael P, Craig, Jonathan M, Karadeema, Rebekah J, Noakes, Matthew T, Kim, Hwanhee C, Abell, Sarah J, Huang, Jesse R, Anderson, Brooke A, Krishnamurthy, Ramanarayanan, Gundlach, Jens H, Romesberg, Floyd E
Published in Journal of the American Chemical Society (05.02.2020)
Published in Journal of the American Chemical Society (05.02.2020)
Get full text
Journal Article
Sequence-dependent mechanochemical coupling of helicase translocation and unwinding at single-nucleotide resolution
Laszlo, Andrew H, Craig, Jonathan M, Gavrilov, Momčilo, Tippana, Ramreddy, Nova, Ian C, Huang, Jesse R, Kim, Hwanhee C, Abell, Sarah J, deCampos-Stairiker, Mallory, Mount, Jonathan W, Bowman, Jasmine L, Baker, Katherine S, Higinbotham, Hugh, Bobrovnikov, Dmitriy, Ha, Taekjip, Gundlach, Jens H
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2022)
Get full text
Journal Article
C-Glycoside DNA bases from an artificially expanded genetic information system reduce processivity in a SF2 helicase as revealed by nanopore tweezers
Thomas, Christopher A., Craig, Jonathan M., Hoshika, Shuichi, Laszlo, Andrew H., Huang, Jesse R., Abell, Sarah J., Kim, Hwanhee C., Carrasco, Jessica, Franzi, Michaela C., Benner, Steven A., Gundlach, Jens H.
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
Get full text
Journal Article
SV40 Large T Antigen Helicase Unwinds Double-Stranded DNA in Single-Nucleotide Steps as Revealed by Nanopore Tweezers
Thomas, Christopher A., Craig, Jonathan M., Laszlo, Andrew H., Nova, Ian C., Xie, Sherry, Huang, Jesse R., Kim, Hwanhee C., Abell, Sarah J., Yardimci, Hasan, Gundlach, Jens H.
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
Get full text
Journal Article
Uncovering the Molecular Basis for Sequence-Dependent Translocation in a Superfamily 2 Helicase using High-Resolution Nanopore Tweezers
Craig, Jonathan M., Marx, Sinduja K., Laszlo, Andrew H., Nova, Ian C., Kim, Hwanhee C., Huang, Jesse R., Abell, Sarah J., Gundlach, Jens H.
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
Get full text
Journal Article
Inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution
Marx, Sinduja K, Mickolajczyk, Keith J, Craig, Jonathan M, Thomas, Christopher A, Pfeffer, Akira M, Abell, Sarah J, Carrasco, Jessica D, Franzi, Michaela C, Huang, Jesse R, Kim, Hwanhee C, Brinkerhoff, Henry D, Kapoor, Tarun M, Gundlach, Jens H, Laszlo, Andrew H
Published in bioRxiv (08.10.2022)
Published in bioRxiv (08.10.2022)
Get full text
Paper
Secondary Structure Detection Through Direct Nanopore RNA Sequencing
Shaw, Alan, Craig, Jonathan M, Amiri, Hossein, Kim, Jeonghoon, Upton, Heather E, Pimentel, Sydney C, Huang, Jesse R, Marqusee, Susan, Gundlach, Jens H, Collins, Kathleen, Bustamante, Carlos J
Published in bioRxiv : the preprint server for biology (05.04.2023)
Get more information
Published in bioRxiv : the preprint server for biology (05.04.2023)
Journal Article
Inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution
Marx, Sinduja K, Mickolajczyk, Keith J, Craig, Jonathan M, Thomas, Christopher A, Pfeffer, Akira M, Abell, Sarah J, Carrasco, Jessica D, Franzi, Michaela C, Huang, Jesse R, Kim, Hwanhee C, Brinkerhoff, Henry D, Kapoor, Tarun M, Gundlach, Jens H, Laszlo, Andrew H
Published in bioRxiv : the preprint server for biology (08.10.2022)
Get more information
Published in bioRxiv : the preprint server for biology (08.10.2022)
Journal Article
Nanopore tweezers measurements of RecQ conformational changes reveal the energy landscape of helicase motion
Craig, Jonathan M, Mills, Maria, Laszlo, Andrew, Kim, Hwanhee C, Abell, Sarah J, Huang, Jesse R, Mount, Jonathan W, Neuman, Keir C, Gundlach, Jens H
Published in bioRxiv (23.09.2021)
Published in bioRxiv (23.09.2021)
Get full text
Paper
Sequence-dependent mechanochemical coupling of helicase translocation and unwinding at single-nucleotide resolution
Laszlo, Andrew H, Craig, Jonathan M, Gavrilov, Momčilo, Tippana, Ramreddy, Nova, Ian C, Huang, Jesse R, Kim, Hwanhee C, Abell, Sarah J, Mallory Decampos-Stairiker, Mount, Jonathan W, Bowman, Jasmine L, Baker, Katherine S, Higinbotham, Hugh, Bobrovnikov, Dmitriy, Ha, Taekjip, Gundlach, Jens H
Published in bioRxiv (11.02.2022)
Published in bioRxiv (11.02.2022)
Get full text
Paper