X-CHIME enables combinatorial, inducible, lineage-specific and sequential knockout of genes in the immune system
LaFleur, Martin W., Lemmen, Ashlyn M., Streeter, Ivy S. L., Nguyen, Thao H., Milling, Lauren E., Derosia, Nicole M., Hoffman, Zachary M., Gillis, Jacob E., Tjokrosurjo, Qin, Markson, Samuel C., Huang, Amy Y., Anekal, Praju V., Montero Llopis, Paula, Haining, W. Nicholas, Doench, John G., Sharpe, Arlene H.
Published in Nature immunology (01.01.2024)
Published in Nature immunology (01.01.2024)
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Epigenetic tuning of PD-1 expression improves exhausted T cell function and viral control
Weiss, Sarah A., Huang, Amy Y., Fung, Megan E., Martinez, Daniela, Chen, Alex C. Y., LaSalle, Thomas J., Miller, Brian C., Scharer, Christopher D., Hegde, Mudra, Nguyen, Thao H., Rowe, Jared H., Osborn, Jossef F., Patterson, Dillon G., Sifnugel, Natalia, Mei-An Nolan, C., Davidson, Richard A., Schwartz, Marc A., Bally, Alexander P. R., Neeld, Dennis K., LaFleur, Martin W., Boss, Jeremy M., Doench, John G., Nicholas Haining, W., Sharpe, Arlene H., Sen, Debattama R.
Published in Nature immunology (01.10.2024)
Published in Nature immunology (01.10.2024)
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Collaboration Platforms in China for Translational and Clinical Research: The Partnership Between Peking University Health Science Center and the University of Michigan Medical School
Kolars, Joseph C, Fang, Weigang, Zheng, Kai, Huang, Amy Y, Sun, Qiudan, Wang, Yanfang, Woolliscroft, James O, Ke, Yang
Published in Academic medicine (01.03.2017)
Published in Academic medicine (01.03.2017)
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Age-associated contraction of tumor-specific T cells impairs antitumor immunity
Georgiev, Peter, Han, SeongJun, Huang, Amy Y, Nguyen, Thao H, Drijvers, Jefte M, Creasey, Hannah, Pereira, Joseph A, Yao, Cong-Hui, Park, Joon Seok, Conway, Thomas S, Fung, Megan E, Liang, Dan, Peluso, Michael, Joshi, Shakchhi, Rowe, Jared H, Miller, Brian C, Freeman, Gordon J, Sharpe, Arlene H, Haigis, Marcia C, Ringel, Alison E
Published in Cancer immunology research (24.08.2024)
Published in Cancer immunology research (24.08.2024)
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Chemical screen to reduce sterol accumulation in Niemann–Pick C disease cells identifies novel lysosomal acid lipase inhibitors
Rosenbaum, Anton I., Rujoi, Madalina, Huang, Amy Y., Du, Hong, Grabowski, Gregory A., Maxfield, Frederick R.
Published in Biochimica et biophysica acta (01.12.2009)
Published in Biochimica et biophysica acta (01.12.2009)
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Endocytosed cation-independent mannose 6-phosphate receptor traffics via the endocytic recycling compartment en route to the trans-Golgi network and a subpopulation of late endosomes
Lin, Sharron X, Mallet, William G, Huang, Amy Y, Maxfield, Frederick R
Published in Molecular biology of the cell (01.02.2004)
Published in Molecular biology of the cell (01.02.2004)
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Investigation of N-Aryl-3-alkylidenepyrrolinones as Potential Niemann−Pick Type C Disease Therapeutics
Cosner, Casey C, Markiewicz, John T, Bourbon, Pauline, Mariani, Christopher J, Wiest, Olaf, Rujoi, Madalina, Rosenbaum, Anton I, Huang, Amy Y, Maxfield, Frederick R, Helquist, Paul
Published in Journal of medicinal chemistry (22.10.2009)
Published in Journal of medicinal chemistry (22.10.2009)
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Resting (Basal) Secretion of Proteins Is Provided by the Minor Regulated and Constitutive-like Pathways and Not Granule Exocytosis in Parotid Acinar Cells
Huang, Amy Y., Castle, Anna M., Hinton, Barry T., Castle, J. David
Published in The Journal of biological chemistry (22.06.2001)
Published in The Journal of biological chemistry (22.06.2001)
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Abstract 3249: Circulating cytokine associations with clinical outcomes in melanoma patients treated with checkpoint inhibitors
Chen, Jiajia, Tarantino, Giuseppe, Severgnini, Mariano, Baginska, Joanna, Giobbie-Hurder, Anita, Manos, Michael, Russell, Janice D., Weirather, Jason L., Pfaff, Kathleen, Huang, Amy Y., Rodig, Scott J., Ranashinge, Srinika, Liu, David, Hodi, F.Stephen
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 3271: Multiomic meta-analysis of differential response to PD-1 and CTLA-4 blockade in metastatic melanoma
Huang, Amy Y., Vokes, Natalie, Ricker, Cora, Aprati, Tyler, Robitschek, Emily, Yang, Jiekun, Ho, Li-Lun, Galani, Kyriakitsa, Burke, Kelly P., Tarantino, Giuseppe, Chen, Jiajia, Sharpe, Arlene H., Van Allen, Eliezer M., Kellis, Manolis, Boland, Genevieve M., Liu, David
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 965: Genomic heterogeneity and ploidy identify patients with intrinsic resistance to PD-1 blockade in metastatic melanoma
Tarantino, Giuseppe, Ricker, Cora A., Wang, Annette, Ge, Will, Huang, Amy Y., Madha, Shariq, Chen, Jiajia, Shi, Yingxiao, Frederick, Dennie T., Freeman, Samuel, Holovatska, Marta M., Manos, Michael P., Zimmer, Lisa, Rösch, Alexander, Zaremba, Anne, Reardon, Brendan, Park, Jihye, Elmarakeby, Haitham, Schilling, Bastian, Giobbie-Hurder, Anita, Vokes, Natalie, Buchbinder, Elizabeth I., Flaherty, Keith, Haq, Rizwan, Wu, Catherine, Boland, Genevieve, Hodi, F. Stephen, Van Allen, Eliezer, Schadendorf, Dirk, Liu, David
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Cross-domain information fusion for enhanced cell population delineation in single-cell spatial-omics data
Zhu, Bokai, Gao, Sheng, Chen, Shuxiao, Yeung, Jason, Bai, Yunhao, Huang, Amy Y, Yeo, Yao Yu, Liao, Guanrui, Mao, Shulin, Jiang, Zhenghui G, Rodig, Scott J, Shalek, Alex K, Nolan, Garry P, Jiang, Sizun, Ma, Zongming
Published in bioRxiv (14.05.2024)
Published in bioRxiv (14.05.2024)
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