Discovery of New Small Molecule Hits as Hepatitis B Virus Capsid Assembly Modulators: Structure and Pharmacophore-Based Approaches
Senaweera, Sameera, Du, Haijuan, Zhang, Huanchun, Kirby, Karen A, Tedbury, Philip R, Xie, Jiashu, Sarafianos, Stefan G, Wang, Zhengqiang
Published in Viruses (27.04.2021)
Published in Viruses (27.04.2021)
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Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules
Vernekar, Sanjeev Kumar V, Sahani, Rajkumar Lalji, Casey, Mary C, Kankanala, Jayakanth, Wang, Lei, Kirby, Karen A, Du, Haijuan, Zhang, Huanchun, Tedbury, Philip R, Xie, Jiashu, Sarafianos, Stefan G, Wang, Zhengqiang
Published in Viruses (16.04.2020)
Published in Viruses (16.04.2020)
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mRNA-binding protein ZFP36 is expressed in atherosclerotic lesions and reduces inflammation in aortic endothelial cells
Zhang, Huanchun, Taylor, W Robert, Joseph, Giji, Caracciolo, Valentina, Gonzales, Donna M, Sidell, Neil, Seli, Emre, Blackshear, Perry J, Kallen, Caleb B
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2013)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2013)
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Novel PF74-like small molecules targeting the HIV-1 capsid protein: Balance of potency and metabolic stability
Wang, Lei, Casey, Mary C., Vernekar, Sanjeev Kumar V., Sahani, Rajkumar Lalji, Kirby, Karen A., Du, Haijuan, Zhang, Huanchun, Tedbury, Philip R., Xie, Jiashu, Sarafianos, Stefan G., Wang, Zhengqiang
Published in Acta pharmaceutica Sinica. B (01.03.2021)
Published in Acta pharmaceutica Sinica. B (01.03.2021)
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Design, Synthesis and Characterization of HIV-1 CA-Targeting Small Molecules: Conformational Restriction of PF74
Sahani, Rajkumar Lalji, Diana-Rivero, Raquel, Vernekar, Sanjeev Kumar V, Wang, Lei, Du, Haijuan, Zhang, Huanchun, Castaner, Andres Emanuelli, Casey, Mary C, Kirby, Karen A, Tedbury, Philip R, Xie, Jiashu, Sarafianos, Stefan G, Wang, Zhengqiang
Published in Viruses (15.03.2021)
Published in Viruses (15.03.2021)
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Lysophosphatidic Acid Facilitates Proliferation of Colon Cancer Cells via Induction of Krüppel-like Factor 5
Zhang, Huanchun, Bialkowska, Agnieszka, Rusovici, Raluca, Chanchevalap, Sengthong, Shim, Hyunsuk, Katz, Jonathan P., Yang, Vincent W., Yun, C. Chris
Published in The Journal of biological chemistry (25.05.2007)
Published in The Journal of biological chemistry (25.05.2007)
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Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway
TAN, Chalet, DE NORONHA, Rita G, WEI ZHOU, OLSON, Jeffrey J, PEREIRA, M. Manuela, NICOLAOU, K. C, VAN MEIR, Erwin G, ROECKER, Anthony J, PYRZYNSKA, Beata, KHWAJA, Fatima, ZHAOBIN ZHANG, HUANCHUN ZHANG, QUINCY TENG, NICHOLSON, Ainsley C, GIANNAKAKOU, Paraskevi
Published in Cancer research (Chicago, Ill.) (15.01.2005)
Published in Cancer research (Chicago, Ill.) (15.01.2005)
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Discovery of Nirmatrelvir Resistance Mutations in SARS-CoV-2 3CLpro: A Computational-Experimental Approach
Havranek, Brandon, Demissie, Robel, Lee, Hyun, Lan, Shuiyun, Zhang, Huanchun, Sarafianos, Stefanos, Ayitou, Anoklase Jean-Luc, Islam, Shahidul M
Published in Journal of chemical information and modeling (27.11.2023)
Published in Journal of chemical information and modeling (27.11.2023)
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Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease
Amblard, Franck, LeCher, Julia C., De, Ramyani, Zhou, Shaoman, Liu, Peng, Goh, Shu Ling, Tao, Sijia, Patel, Dharmeshkumar, Downs-Bowen, Jessica, Zandi, Keivan, Zhang, Huanchun, Chaudhry, Gitika, McBrayer, Tamara, Muczynski, Michael, Al-Homoudi, Abdullah, Engel, Joseph, Lan, Shuiyun, Sarafianos, Stefan G., Kovari, Ladislau C., Schinazi, Raymond F.
Published in European journal of medicinal chemistry (15.03.2024)
Published in European journal of medicinal chemistry (15.03.2024)
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Journal Article
Chemical profiling of HIV-1 capsid-targeting antiviral PF74
Wang, Lei, Casey, Mary C., Vernekar, Sanjeev Kumar V., Do, Ha T., Sahani, Rajkumar Lalji, Kirby, Karen A., Du, Haijuan, Hachiya, Atsuko, Zhang, Huanchun, Tedbury, Philip R., Xie, Jiashu, Sarafianos, Stefan G., Wang, Zhengqiang
Published in European journal of medicinal chemistry (15.08.2020)
Published in European journal of medicinal chemistry (15.08.2020)
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Journal Article
Novel HIV-1 capsid-targeting small molecules of the PF74 binding site
Wang, Lei, Casey, Mary C., Vernekar, Sanjeev Kumar V., Sahani, Rajkumar Lalji, Kankanala, Jayakanth, Kirby, Karen A., Du, Haijuan, Hachiya, Atsuko, Zhang, Huanchun, Tedbury, Philip R., Xie, Jiashu, Sarafianos, Stefan G., Wang, Zhengqiang
Published in European journal of medicinal chemistry (15.10.2020)
Published in European journal of medicinal chemistry (15.10.2020)
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Journal Article
Potency and metabolic stability: a molecular hybrid case in the design of novel PF74-like small molecules targeting HIV-1 capsid protein
Sahani, Rajkumar Lalji, Akther, Thamina, Cilento, Maria E, Castaner, Andres Emanuelli, Zhang, Huanchun, Kirby, Karen A, Xie, Jiashu, Sarafianos, Stefan G, Wang, Zhengqiang
Published in MedChemComm (15.12.2021)
Published in MedChemComm (15.12.2021)
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The mRNA-Binding Protein Zfp36 Is Upregulated by β-Adrenergic Stimulation and Represses IL-6 Production in 3T3-L1 Adipocytes
Brahma, Pavna K., Zhang, Huanchun, Murray, Betsy S., Shu, Feng‐jue, Sidell, Neil, Seli, Emre, Kallen, Caleb B.
Published in Obesity (Silver Spring, Md.) (01.01.2012)
Published in Obesity (Silver Spring, Md.) (01.01.2012)
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MAGI-3 regulates LPA-induced activation of Erk and RhoA
Zhang, Huanchun, Wang, Dongsheng, Sun, Hong, Hall, Randy A., Yun, C. Chris
Published in Cellular signalling (01.02.2007)
Published in Cellular signalling (01.02.2007)
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