Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13
Liu, Junli, Xia, Hongguang, Kim, Minsu, Xu, Lihua, Li, Ying, Zhang, Lihong, Cai, Yu, Norberg, Helin Vakifahmetoglu, Zhang, Tao, Furuya, Tsuyoshi, Jin, Minzhi, Zhu, Zhimin, Wang, Huanchen, Yu, Jia, Li, Yanxia, Hao, Yan, Choi, Augustine, Ke, Hengming, Ma, Dawei, Yuan, Junying
Published in Cell (30.09.2011)
Published in Cell (30.09.2011)
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Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte
Norris, Rachael P, Ratzan, William J, Freudzon, Marina, Mehlmann, Lisa M, Krall, Judith, Movsesian, Matthew A, Wang, Huanchen, Ke, Hengming, Nikolaev, Viacheslav O, Jaffe, Laurinda A
Published in Development (Cambridge) (01.06.2009)
Published in Development (Cambridge) (01.06.2009)
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Synthesis of Densely Phosphorylated Bis-1,5-Diphospho-myo-Inositol Tetrakisphosphate and its Enantiomer by Bidirectional P-Anhydride Formation
Capolicchio, Samanta, Wang, Huanchen, Thakor, Divyeshsinh T., Shears, Stephen B., Jessen, Henning J.
Published in Angewandte Chemie International Edition (01.09.2014)
Published in Angewandte Chemie International Edition (01.09.2014)
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Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell line
Gu, Chunfang, Liu, Juan, Liu, Xiaojing, Zhang, Haibo, Luo, Ji, Wang, Huanchen, Locasale, Jason W., Shears, Stephen B.
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2021)
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Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8
Li, Xingyao, Kirkpatrick, Regan B., Wang, Xiaodong, Tucker, Charles J., Shukla, Anuj, Jessen, Henning J., Wang, Huanchen, Shears, Stephen B., Gu, Chunfang
Published in Cell reports (Cambridge) (25.06.2024)
Published in Cell reports (Cambridge) (25.06.2024)
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A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop
Wang, Huanchen, Perera, Lalith, Jork, Nikolaus, Zong, Guangning, Riley, Andrew M., Potter, Barry V. L., Jessen, Henning J., Shears, Stephen B.
Published in Nature communications (25.04.2022)
Published in Nature communications (25.04.2022)
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High-resolution design of a protein loop
Hu, Xiaozhen, Wang, Huanchen, Ke, Hengming, Kuhlman, Brian
Published in Proceedings of the National Academy of Sciences - PNAS (06.11.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (06.11.2007)
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Structural insight into substrate specificity of phosphodiesterase 10
Wang, Huanchen, Liu, Yudong, Hou, Jing, Zheng, Meiyan, Robinson, Howard, Ke, Hengming
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2007)
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Kinetic and Structural Studies of Phosphodiesterase-8A and Implication on the Inhibitor Selectivity
Wang, Huanchen, Yan, Zier, Yang, Serena, Cai, Jiwen, Robinson, Howard, Ke, Hengming
Published in Biochemistry (Easton) (02.12.2008)
Published in Biochemistry (Easton) (02.12.2008)
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Crystallographic and Nuclear Magnetic Resonance Evaluation of the Impact of Peptide Binding to the Second PDZ Domain of Protein Tyrosine Phosphatase 1E
Zhang, Jun, Sapienza, Paul J, Ke, Hengming, Chang, Aram, Hengel, Sarah R, Wang, Huanchen, Phillips, George N, Lee, Andrew L
Published in Biochemistry (Easton) (02.11.2010)
Published in Biochemistry (Easton) (02.11.2010)
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Retraction: A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors
Baughman, Brandi M, Wang, Huanchen, An, Yi, Kireev, Dmitri, Stashko, Michael A, Jessen, Henning J, Pearce, Kenneth H, Frye, Stephen V, Shears, Stephen B
Published in PloS one (21.06.2017)
Published in PloS one (21.06.2017)
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A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors
Baughman, Brandi M, Wang, Huanchen, An, Yi, Kireev, Dmitri, Stashko, Michael A, Jessen, Henning J, Pearce, Kenneth H, Frye, Stephen V, Shears, Stephen B
Published in PloS one (13.10.2016)
Published in PloS one (13.10.2016)
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Conformational Variations of Both Phosphodiesterase-5 and Inhibitors Provide the Structural Basis for the Physiological Effects of Vardenafil and Sildenafil
Wang, Huanchen, Ye, Mengchun, Robinson, Howard, Francis, Sharron H, Ke, Hengming
Published in Molecular pharmacology (01.01.2008)
Published in Molecular pharmacology (01.01.2008)
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Design, Synthesis, and Structure−Activity Relationship, Molecular Modeling, and NMR Studies of a Series of Phenyl Alkyl Ketones as Highly Potent and Selective Phosphodiesterase-4 Inhibitors
Zheng, Shilong, Kaur, Gurpreet, Wang, Huanchen, Li, Minyong, Macnaughtan, Megan, Yang, Xiaochuan, Reid, Suazette, Prestegard, James, Wang, Binghe, Ke, Hengming
Published in Journal of medicinal chemistry (25.12.2008)
Published in Journal of medicinal chemistry (25.12.2008)
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