Search Results - "Hu, Shi Quan" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists

Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists

by Smith, Brian J, Huang, Kun, Kong, Geoffrey, Chan, Shu Jin, Nakagawa, Satoe, Menting, John G, Hu, Shi-Quan, Whittaker, Jonathan, Steiner, Donald F, Katsoyannis, Panayotis G, Ward, Colin W, Weiss, Michael A, Lawrence, Michael C
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.2010)

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Diabetes-Associated Mutations in Insulin Identify Invariant Receptor Contacts

Diabetes-Associated Mutations in Insulin Identify Invariant Receptor Contacts

by Xu, Bin, Hu, Shi-Quan, Chu, Ying-Chi, Wang, Shuhua, Wang, Run-Ying, Nakagawa, Satoe H, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Diabetes (New York, N.Y.) (01.06.2004)

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Achilles' Heel in an Amyloidogenic Protein and Its Repair: INSULIN FIBRILLATION AND THERAPEUTIC DESIGN

Achilles' Heel in an Amyloidogenic Protein and Its Repair: INSULIN FIBRILLATION AND THERAPEUTIC DESIGN

by Yang, Yanwu, Petkova, Aneta, Huang, Kun, Xu, Bin, Hua, Qing-xin, Ye, I. Ju, Chu, Ying-Chi, Hu, Shi-Quan, Phillips, Nelson B, Whittaker, Jonathan, Ismail-Beigi, Faramarz, Mackin, Robert B, Katsoyannis, Panayotis G, Tycko, Robert, Weiss, Michael A
Published in The Journal of biological chemistry (02.04.2010)

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Design of an Active Ultrastable Single-chain Insulin Analog: SYNTHESIS, STRUCTURE, AND THERAPEUTIC IMPLICATIONS

Design of an Active Ultrastable Single-chain Insulin Analog: SYNTHESIS, STRUCTURE, AND THERAPEUTIC IMPLICATIONS

by Hua, Qing-xin, Nakagawa, Satoe H, Jia, Wenhua, Huang, Kun, Phillips, Nelson B, Hu, Shi-quan, Weiss, Michael A
Published in The Journal of biological chemistry (23.05.2008)

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Activities of Monomeric Insulin Analogs at Position A8 Are Uncorrelated with Their Thermodynamic Stabilities

Activities of Monomeric Insulin Analogs at Position A8 Are Uncorrelated with Their Thermodynamic Stabilities

by Weiss, Michael A., Hua, Qing-Xin, Jia, Wenhua, Nakagawa, Satoe H., Chu, Ying-Chi, Hu, Shi-Quan, Katsoyannis, Panayotis G.
Published in The Journal of biological chemistry (26.10.2001)

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Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS

Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS

by Hua, Qing-xin, Xu, Bin, Huang, Kun, Hu, Shi-Quan, Nakagawa, Satoe, Jia, Wenhua, Wang, Shuhua, Whittaker, Jonathan, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (22.05.2009)

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Decoding the Cryptic Active Conformation of a Protein by Synthetic Photoscanning: INSULIN INSERTS A DETACHABLE ARM BETWEEN RECEPTOR DOMAINS

Decoding the Cryptic Active Conformation of a Protein by Synthetic Photoscanning: INSULIN INSERTS A DETACHABLE ARM BETWEEN RECEPTOR DOMAINS

by Xu, Bin, Huang, Kun, Chu, Ying-Chi, Hu, Shi-Quan, Nakagawa, Satoe, Wang, Shuhua, Wang, Run-Ying, Whittaker, Jonathan, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (22.05.2009)

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Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain

Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain

by Hua, Qing-Xin, Nakagawa, Satoe, Hu, Shi-Quan, Jia, Wenhua, Wang, Shuhua, Weiss, Michael A
Published in The Journal of biological chemistry (25.08.2006)

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Supramolecular Protein Engineering: DESIGN OF ZINC-STAPLED INSULIN HEXAMERS AS A LONG ACTING DEPOT

Supramolecular Protein Engineering: DESIGN OF ZINC-STAPLED INSULIN HEXAMERS AS A LONG ACTING DEPOT

by Phillips, Nelson B, Wan, Zhu-li, Whittaker, Linda, Hu, Shi-Quan, Huang, Kun, Hua, Qing-xin, Whittaker, Jonathan, Ismail-Beigi, Faramarz, Weiss, Michael A
Published in The Journal of biological chemistry (16.04.2010)

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Deciphering the Hidden Informational Content of Protein Sequences: FOLDABILITY OF PROINSULIN HINGES ON A FLEXIBLE ARM THAT IS DISPENSABLE IN THE MATURE HORMONE

Deciphering the Hidden Informational Content of Protein Sequences: FOLDABILITY OF PROINSULIN HINGES ON A FLEXIBLE ARM THAT IS DISPENSABLE IN THE MATURE HORMONE

by Liu, Ming, Hua, Qing-xin, Hu, Shi-Quan, Jia, Wenhua, Yang, Yanwu, Saith, Sunil Evan, Whittaker, Jonathan, Arvan, Peter, Weiss, Michael A
Published in The Journal of biological chemistry (01.10.2010)

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Structure of a Mutant Insulin Uncouples Receptor Binding from Protein Allostery: AN ELECTROSTATIC BLOCK TO THE TR TRANSITION

Structure of a Mutant Insulin Uncouples Receptor Binding from Protein Allostery: AN ELECTROSTATIC BLOCK TO THE TR TRANSITION

by Wan, Zhu-li, Huang, Kun, Hu, Shi-Quan, Whittaker, Jonathan, Weiss, Michael A
Published in The Journal of biological chemistry (25.07.2008)

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Contribution of Residue B5 to the Folding and Function of Insulin and IGF-I: CONSTRAINTS AND FINE-TUNING IN THE EVOLUTION OF A PROTEIN FAMILY

Contribution of Residue B5 to the Folding and Function of Insulin and IGF-I: CONSTRAINTS AND FINE-TUNING IN THE EVOLUTION OF A PROTEIN FAMILY

by Sohma, Youhei, Hua, Qing-xin, Liu, Ming, Phillips, Nelson B, Hu, Shi-Quan, Whittaker, Jonathan, Whittaker, Linda J, Ng, Aubree, Roberts, Charles T. Jr, Arvan, Peter, Kent, Stephen B.H, Weiss, Michael A
Published in The Journal of biological chemistry (12.02.2010)

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Chiral Mutagenesis of Insulin: CONTRIBUTION OF THE B20-B23 β-TURN TO ACTIVITY AND STABILITY

Chiral Mutagenesis of Insulin: CONTRIBUTION OF THE B20-B23 β-TURN TO ACTIVITY AND STABILITY

by Nakagawa, Satoe H, Hua, Qing-xin, Hu, Shi-Quan, Jia, Wenhua, Wang, Shuhua, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (04.08.2006)

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How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor

How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor

by Huang, Kun, Xu, Bin, Hu, Shi-Quan, Chu, Ying-Chi, Hua, Qing-Xin, Qu, Yan, Li, Biaoru, Wang, Shuhua, Wang, Run-Ying, Nakagawa, Satoe H, Theede, Anne Mette, Whittaker, Jonathan, De Meyts, Pierre, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Journal of molecular biology (06.08.2004)

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Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama

Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama

by Wan, Zhu-li, Huang, Kun, Xu, Bin, Hu, Shi-Quan, Wang, Shuhua, Chu, Ying-Chi, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (05.04.2005)

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The Structure of a Mutant Insulin Uncouples Receptor Binding from Protein Allostery

The Structure of a Mutant Insulin Uncouples Receptor Binding from Protein Allostery

by Wan, Zhu-li, Huang, Kun, Hu, Shi-Quan, Whittaker, Jonathan, Weiss, Michael A.
Published in The Journal of biological chemistry (25.07.2008)

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Contribution of Residue B5 to the Folding and Function of Insulin and IGF-I

Contribution of Residue B5 to the Folding and Function of Insulin and IGF-I

by Sohma, Youhei, Hua, Qing-xin, Liu, Ming, Phillips, Nelson B., Hu, Shi-Quan, Whittaker, Jonathan, Whittaker, Linda J., Ng, Aubree, Roberts, Charles T., Arvan, Peter, Kent, Stephen B.H., Weiss, Michael A.
Published in The Journal of biological chemistry (12.02.2010)

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Enhancing the Activity of a Protein by Stereospecific Unfolding

Enhancing the Activity of a Protein by Stereospecific Unfolding

by Hua, Qing-xin, Xu, Bin, Huang, Kun, Hu, Shi-Quan, Nakagawa, Satoe, Jia, Wenhua, Wang, Shuhua, Whittaker, Jonathan, Katsoyannis, Panayotis G., Weiss, Michael A.
Published in The Journal of biological chemistry (22.05.2009)

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Decoding the Cryptic Active Conformation of a Protein by Synthetic Photoscanning

Decoding the Cryptic Active Conformation of a Protein by Synthetic Photoscanning

by Xu, Bin, Huang, Kun, Chu, Ying-Chi, Hu, Shi-Quan, Nakagawa, Satoe, Wang, Shuhua, Wang, Run-Ying, Whittaker, Jonathan, Katsoyannis, Panayotis G., Weiss, Michael A.
Published in The Journal of biological chemistry (22.05.2009)

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Design of an Active Ultrastable Single-chain Insulin Analog

Design of an Active Ultrastable Single-chain Insulin Analog

by Hua, Qing-xin, Nakagawa, Satoe H., Jia, Wenhua, Huang, Kun, Phillips, Nelson B., Hu, Shi-quan, Weiss, Michael A.
Published in The Journal of biological chemistry (23.05.2008)

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