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Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
Zuris, John A, Thompson, David B, Shu, Yilai, Guilinger, John P, Bessen, Jeffrey L, Hu, Johnny H, Maeder, Morgan L, Joung, J Keith, Chen, Zheng-Yi, Liu, David R
Published in Nature biotechnology (01.01.2015)
Published in Nature biotechnology (01.01.2015)
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Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents
Gao, Xue, Tao, Yong, Lamas, Veronica, Huang, Mingqian, Yeh, Wei-Hsi, Pan, Bifeng, Hu, Yu-Juan, Hu, Johnny H., Thompson, David B., Shu, Yilai, Li, Yamin, Wang, Hongyang, Yang, Shiming, Xu, Qiaobing, Polley, Daniel B., Liberman, M. Charles, Kong, Wei-Jia, Holt, Jeffrey R., Chen, Zheng-Yi, Liu, David R.
Published in Nature (London) (11.01.2018)
Published in Nature (London) (11.01.2018)
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Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo
Tao, Yong, Lamas, Veronica, Du, Wan, Zhu, Wenliang, Li, Yiran, Whittaker, Madelynn N., Zuris, John A., Thompson, David B., Rameshbabu, Arun Prabhu, Shu, Yilai, Gao, Xue, Hu, Johnny H., Pei, Charles, Kong, Wei-Jia, Liu, Xuezhong, Wu, Hao, Kleinstiver, Benjamin P., Liu, David R., Chen, Zheng-Yi
Published in Nature communications (15.08.2023)
Published in Nature communications (15.08.2023)
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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity
Hu, Johnny H., Miller, Shannon M., Geurts, Maarten H., Tang, Weixin, Chen, Liwei, Sun, Ning, Zeina, Christina M., Gao, Xue, Rees, Holly A., Lin, Zhi, Liu, David R.
Published in Nature (London) (05.04.2018)
Published in Nature (London) (05.04.2018)
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Structure and mechanism of the UvrA–UvrB DNA damage sensor
Pakotiprapha, Danaya, Samuels, Martin, Shen, Koning, Hu, Johnny H, Jeruzalmi, David
Published in Nature structural & molecular biology (01.03.2012)
Published in Nature structural & molecular biology (01.03.2012)
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CRISPR/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells
Sharma, Arun, Toepfer, Christopher N, Ward, Tarsha, Wasson, Lauren, Agarwal, Radhika, Conner, David A, Hu, Johnny H, Seidman, Christine E
Published in Current protocols in human genetics (24.01.2018)
Published in Current protocols in human genetics (24.01.2018)
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Efficient Delivery of Genome-Editing Proteins In Vitro and In Vivo
Zuris, John A., Thompson, David B., Shu, Yilai, Guilinger, John P., Bessen, Jeffrey L., Hu, Johnny H., Maeder, Morgan L., Joung, J. Keith, Chen, Zheng-Yi, Liu, David R.
Published in Nature biotechnology (30.10.2014)
Published in Nature biotechnology (30.10.2014)
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