BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor
Tsai, Hui‐Jen, Jiaang, Weir‐Torn, Shih, Neng‐Yao, Fletcher, Jonathan A., Lin, Ming‐Jon, Yang, Ming‐Yu, Chen, Chiung‐Tong, Hsu, Tsu‐An John, Wu, Chun‐Chieh, Lin, Hui‐You, Chen, Li‐Tzong
Published in Cancer science (01.11.2018)
Published in Cancer science (01.11.2018)
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Journal Article
The Effects of Aβ1-42 Binding to the SARS-CoV-2 Spike Protein S1 Subunit and Angiotensin-Converting Enzyme 2
Hsu, John Tsu-An, Tien, Chih-Feng, Yu, Guann-Yi, Shen, Santai, Lee, Yi-Hsuan, Hsu, Pei-Chien, Wang, Yun, Chao, Po-Kuan, Tsay, Huey-Jen, Shie, Feng-Shiun
Published in International journal of molecular sciences (30.07.2021)
Published in International journal of molecular sciences (30.07.2021)
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Journal Article
Zika Virus NS3 Protease Pharmacophore Anchor Model and Drug Discovery
Pathak, Nikhil, Kuo, Yi-Ping, Chang, Teng-Yuan, Huang, Chin-Ting, Hung, Hui-Chen, Hsu, John Tsu-An, Yu, Guann-Yi, Yang, Jinn-Moon
Published in Scientific reports (02.06.2020)
Published in Scientific reports (02.06.2020)
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Journal Article
Reducing brain Aβ burden ameliorates high-fat diet-induced fatty liver disease in APP/PS1 mice
Tsay, Huey-Jen, Gan, Yu-Ling, Su, Yu-Han, Sun, Yu-Yo, Yao, Heng-Hsiang, Chen, Hui-Wen, Hsu, Ying-Ting, Hsu, John Tsu-An, Wang, Horng-Dar, Shie, Feng-Shiun
Published in Biomedicine & pharmacotherapy (01.04.2024)
Published in Biomedicine & pharmacotherapy (01.04.2024)
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Journal Article
The Beneficial Effects of Combining Anti-Aβ Antibody NP106 and Curcumin Analog TML-6 on the Treatment of Alzheimer's Disease in APP/PS1 Mice
Su, Ih-Jen, Hsu, Chia-Yu, Shen, Santai, Chao, Po-Kuan, Hsu, John Tsu-An, Hsueh, Jung-Tsung, Liang, Jia-Jun, Hsu, Ying-Ting, Shie, Feng-Shiun
Published in International journal of molecular sciences (05.01.2022)
Published in International journal of molecular sciences (05.01.2022)
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Journal Article
Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice
Chao, Po-Kuan, Chang, Hsiao-Fu, Ou, Li-Chin, Chuang, Jian-Ying, Lee, Pin-Tse, Chang, Wan-Ting, Chen, Shu-Chun, Ueng, Shau-Hua, Hsu, John Tsu-An, Tao, Pao-Luh, Law, Ping-Yee, Loh, Horace H., Yeh, Shiu-Hwa
Published in Scientific reports (20.02.2019)
Published in Scientific reports (20.02.2019)
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Journal Article
BPR1J373, an Oral Multiple Tyrosine Kinase Inhibitor, Targets c-KIT for the Treatment of c-KIT-Driven Myeloid Leukemia
Chen, Li-Tzong, Chen, Chiung-Tong, Jiaang, Weir-Torn, Chen, Tsai-Yun, Butterfield, Joseph H, Shih, Neng-Yao, Hsu, John Tsu-An, Lin, Hui-You, Lin, Sheng-Fung, Tsai, Hui-Jen
Published in Molecular cancer therapeutics (01.10.2016)
Published in Molecular cancer therapeutics (01.10.2016)
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Bispecific Antibody Conjugated Manganese-Based Magnetic Engineered Iron Oxide for Imaging of HER2/neu- and EGFR-Expressing Tumors
Wu, Shou-Cheng, Chen, Yu-Jen, Wang, Hsiang-Ching, Chou, Min-Yuan, Chang, Teng-Yuan, Yuan, Shyng-Shiou, Chen, Chiao-Yun, Hou, Ming-Feng, Hsu, John Tsu-An, Wang, Yun-Ming
Published in Theranostics (2016)
Published in Theranostics (2016)
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Papain-Like Protease 2 (PLP2) from Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV): Expression, Purification, Characterization, and Inhibition
Han, Yu-San, Chang, Gu-Gang, Juo, Chiun-Gung, Lee, Hong-Jen, Yeh, Shiou-Hwei, Hsu, John Tsu-An, Chen, Xin
Published in Biochemistry (Easton) (02.08.2005)
Published in Biochemistry (Easton) (02.08.2005)
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Journal Article
BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71
Velu, Arul Balaji, Chen, Guang-Wu, Hsieh, Po-Ting, Horng, Jim-Tong, Hsu, John Tsu-An, Hsieh, Hsing-Pang, Chen, Tzu-Chun, Weng, Kuo-Feng, Shih, Shin-Ru
Published in Antiviral research (01.12.2014)
Published in Antiviral research (01.12.2014)
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Journal Article
Discovery of M Protease Inhibitors Encoded by SARS-CoV-2
Hung, Hui-Chen, Ke, Yi-Yu, Huang, Sheng Yu, Huang, Peng-Nien, Kung, Yu-An, Chang, Teng-Yuan, Yen, Kuei-Jung, Peng, Tzu-Ting, Chang, Shao-En, Huang, Chin-Ting, Tsai, Ya-Ru, Wu, Szu-Huei, Lee, Shiow-Ju, Lin, Jiunn-Horng, Liu, Bing-Sin, Sung, Wang-Chou, Shih, Shin-Ru, Chen, Chiung-Tong, Hsu, John Tsu-An
Published in Antimicrobial agents and chemotherapy (20.08.2020)
Published in Antimicrobial agents and chemotherapy (20.08.2020)
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Journal Article
Bioassay-guided purification and identification of PPARα/γ agonists from Chlorella sorokiniana
Chou, Yu-Cheng, Prakash, Ekambaranellore, Huang, Chien-Fu, Lien, Tzu-Wen, Chen, Xin, Su, Ih-Jen, Chao, Yu-Sheng, Hsieh, Hsing-Pang, Hsu, John Tsu-An
Published in Phytotherapy research (01.05.2008)
Published in Phytotherapy research (01.05.2008)
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Journal Article
Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors
Peng, Yi-Hui, Shiao, Hui-Yi, Tu, Chih-Hsiang, Liu, Pang-Min, Hsu, John Tsu-An, Amancha, Prashanth Kumar, Wu, Jian-Sung, Coumar, Mohane Selvaraj, Chen, Chun-Hwa, Wang, Sing-Yi, Lin, Wen-Hsing, Sun, Hsu-Yi, Chao, Yu-Sheng, Lyu, Ping-Chiang, Hsieh, Hsing-Pang, Wu, Su-Ying
Published in Journal of medicinal chemistry (23.05.2013)
Published in Journal of medicinal chemistry (23.05.2013)
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Journal Article
BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine
Chao, Po-Kuan, Chang, Hsiao-Fu, Chang, Wan-Ting, Yeh, Teng-Kuang, Ou, Li-Chin, Chuang, Jian-Ying, Tsu-An Hsu, John, Tao, Pao-Luh, Loh, Horace H., Shih, Chuan, Ueng, Shau-Hua, Yeh, Shiu-Hwa
Published in Neuropharmacology (01.04.2020)
Published in Neuropharmacology (01.04.2020)
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Journal Article
Effect of a Neuropilin-1-Derived Virus Receptor Trap on Enterovirus A71 Infection In Vitro
Wang, Hsiang-Ching, Huang, Peng-Nien, Hung, Hui-Chen, Tseng, Sung-Nien, Chang, Chia-Chia, Tsai, Ya-Ru, Wang, Yun-Ming, Shih, Shin-Ru, Hsu, John Tsu-An
Published in Antimicrobial agents and chemotherapy (16.12.2020)
Published in Antimicrobial agents and chemotherapy (16.12.2020)
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Journal Article
Antiviral Activity of a Llama-Derived Single-Domain Antibody against Enterovirus A71
Huang, Peng-Nien, Wang, Hsiang-Ching, Hung, Hui-Chen, Tseng, Sung-Nien, Chang, Teng-Yuan, Chou, Min-Yuan, Chen, Yu-Jen, Wang, Yun-Ming, Shih, Shin-Ru, Hsu, John Tsu-An
Published in Antimicrobial agents and chemotherapy (21.04.2020)
Published in Antimicrobial agents and chemotherapy (21.04.2020)
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Journal Article
Development of a Humanized Antibody Targeting Extracellular HSP90α to Suppress Endothelial-Mesenchymal Transition-Enhanced Tumor Growth of Pancreatic Adenocarcinoma Cells
Fan, Chi-Shuan, Hung, Hui-Chen, Chen, Chia-Chi, Chen, Li-Li, Ke, Yi-Yu, Yeh, Teng-Kuang, Huang, Chin-Ting, Chang, Teng-Yuan, Yen, Kuei-Jung, Chen, Chung-Hsing, Chua, Kee Voon, Hsu, John Tsu-An, Huang, Tze-Sing
Published in Cells (Basel, Switzerland) (04.07.2024)
Published in Cells (Basel, Switzerland) (04.07.2024)
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