Search Results - "Hsu, Ning‐Shian" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry

N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry

by Wang, Yung-Lin, Chang, Chin-Yuan, Hsu, Ning-Shian, Lo, I-Wen, Lin, Kuan-Hung, Chen, Chun-Liang, Chang, Chi-Fon, Wang, Zhe-Chong, Ogasawara, Yasushi, Dairi, Tohru, Maruyama, Chitose, Hamano, Yoshimitsu, Li, Tsung-Lin
Published in Nature communications (03.05.2023)

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Structural and chemical trapping of flavin‐oxide intermediates reveals substrate‐directed reaction multiplicity

Structural and chemical trapping of flavin‐oxide intermediates reveals substrate‐directed reaction multiplicity

by Lin, Kuan‐Hung, Lyu, Syue‐Yi, Yeh, Hsien‐Wei, Li, Yi‐Shan, Hsu, Ning‐Shian, Huang, Chun‐Man, Wang, Yung‐Lin, Shih, Hao‐Wei, Wang, Zhe‐Chong, Wu, Chang‐Jer, Li, Tsung‐Lin
Published in Protein science (01.07.2020)

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Biosynthesis of Streptolidine Involved Two Unexpected Intermediates Produced by a Dihydroxylase and a Cyclase through Unusual Mechanisms

Biosynthesis of Streptolidine Involved Two Unexpected Intermediates Produced by a Dihydroxylase and a Cyclase through Unusual Mechanisms

by Chang, Chin-Yuan, Lyu, Syue-Yi, Liu, Yu-Chen, Hsu, Ning-Shian, Wu, Chih-Chung, Tang, Cheng-Fong, Lin, Kuan-Hung, Ho, Jin-Yuan, Wu, Chang-Jer, Tsai, Ming-Daw, Li, Tsung-Lin
Published in Angewandte Chemie International Edition (10.02.2014)

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The Mesomeric Effect of Thiazolium on non‐Kekulé Diradicals in Pichia stipitis Transketolase

The Mesomeric Effect of Thiazolium on non‐Kekulé Diradicals in Pichia stipitis Transketolase

by Hsu, Ning‐Shian, Wang, Yung‐Lin, Lin, Kuan‐Hung, Chang, Chi‐Fon, Lyu, Syue‐Yi, Hsu, Li‐Jen, Liu, Yu‐Chen, Chang, Chin‐Yuan, Wu, Chang‐Jer, Li, Tsung‐Lin
Published in Angewandte Chemie International Edition (12.02.2018)

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Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto‐Transferring Reactions

Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto‐Transferring Reactions

by Hsu, Ning‐Shian, Wang, Yung‐Lin, Lin, Kuan‐Hung, Chang, Chi‐Fon, Ke, Shyue‐Chu, Lyu, Syue‐Yi, Hsu, Li‐Jen, Li, Yi‐Shan, Chen, Sheng‐Chia, Wang, Kuei‐Chen, Li, Tsung‐Lin
Published in Chembiochem : a European journal of chemical biology (16.11.2018)

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β-Hydroxylation of α-amino-β-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin

β-Hydroxylation of α-amino-β-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin

by Zadeh, Saeid Malek, Chen, Mei-Hua, Wang, Zhe-Chong, Astani, Elahe K., Lo, I-Wen, Lin, Kuan-Hung, Hsu, Ning-Shian, Adhikari, Kamal, Lyu, Syue-Yi, Tsai, Hsin-Ying, Terasawa, Yuma, Yabe, Miyuki, Yamamoto, Kazuki, Ichikawa, Satoshi, Li, Tsung-Lin
Published in Communications chemistry (28.07.2022)

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KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity

KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity

by Rattinam, Rajesh, Basha, R Sidick, Wang, Yung-Lin, Wang, Zhe-Chong, Hsu, Ning-Shian, Lin, Kuan-Hung, Zadeh, Saeid Malek, Adhikari, Kamal, Lin, Jin-Ping, Li, Tsung-Lin
Published in Biomedicines (19.01.2022)

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In vitro Characterization of Enzymes Involved in the Synthesis of Nonproteinogenic Residue (2S,3S)-β-Methylphenylalanine in Glycopeptide Antibiotic Mannopeptimycin

In vitro Characterization of Enzymes Involved in the Synthesis of Nonproteinogenic Residue (2S,3S)-β-Methylphenylalanine in Glycopeptide Antibiotic Mannopeptimycin

by Huang, Yu-Ting, Lyu, Syue-Yi, Chuang, Pei-Hsuan, Hsu, Ning-Shian, Li, Yi-Shan, Chan, Hsiu-Chien, Huang, Chuen-Jiuan, Liu, Yu-Chen, Wu, Chang-Jer, Yang, Wen-Bin, Li, Tsung-Lin
Published in Chembiochem : a European journal of chemical biology (12.10.2009)

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Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase

Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase

by Zou, Xiao-Wei, Liu, Yu-Chen, Hsu, Ning-Shian, Huang, Chuen-Jiuan, Lyu, Syue-Yi, Chan, Hsiu-Chien, Chang, Chin-Yuan, Yeh, Hsien-Wei, Lin, Kuan-Hung, Wu, Chang-Jer, Tsai, Ming-Daw, Li, Tsung-Lin
Published in Acta crystallographica. Section D, Biological crystallography. (01.06.2014)

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Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions

Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions

by Chen, Mei-Hua, Li, Yi-Shan, Hsu, Ning-Shian, Lin, Kuan-Hung, Wang, Yung-Lin, Wang, Zhe-Chong, Chang, Chi-Fon, Lin, Jin-Ping, Chang, Chin-Yuan, Li, Tsung-Lin
Published in ACS catalysis (04.02.2022)

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Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin

Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin

by Pan, Yi-Chi, Wang, Yung-Lin, Toh, Shu-Ing, Hsu, Ning-Shian, Lin, Kuan-Hung, Xu, Zhengren, Huang, Sheng-Cih, Wu, Tung-Kung, Li, Tsung-Lin, Chang, Chin-Yuan
Published in ACS chemical biology (21.01.2022)

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Intermolecular Interactions of Nucleoside Antibiotic Tunicamycin with On-Target MraYCB-TUN and Off-Target DPAGT1-TUN in the Active Sites Delineated by Quantum Mechanics/Molecular Mechanics Calculations

Intermolecular Interactions of Nucleoside Antibiotic Tunicamycin with On-Target MraYCB-TUN and Off-Target DPAGT1-TUN in the Active Sites Delineated by Quantum Mechanics/Molecular Mechanics Calculations

by Astani, Elahe K., Malek Zadeh, Saeid, Hsu, Ning-Shian, Lin, Kuan-Hung, Sardari, Soroush, Li, Tsung-Lin
Published in ACS omega (20.09.2022)

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Biochemical and structural explorations of α‐hydroxyacid oxidases reveal a four‐electron oxidative decarboxylation reaction

Biochemical and structural explorations of α‐hydroxyacid oxidases reveal a four‐electron oxidative decarboxylation reaction

by Yeh, Hsien-Wei, Lin, Kuan-Hung, Lyu, Syue-Yi, Li, Yi-Shan, Huang, Chun-Man, Wang, Yung-Lin, Shih, Hao-Wei, Hsu, Ning-Shian, Wu, Chang-Jer, Li, Tsung-Lin
Published in Acta crystallographica. Section D, Biological crystallography. (01.08.2019)

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The flavin mononucleotide cofactor in α‐hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate‐oxidation level

The flavin mononucleotide cofactor in α‐hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate‐oxidation level

by Lyu, Syue-Yi, Lin, Kuan-Hung, Yeh, Hsien-Wei, Li, Yi-Shan, Huang, Chun-Man, Wang, Yung-Lin, Shih, Hao-Wei, Hsu, Ning-Shian, Wu, Chang-Jer, Li, Tsung-Lin
Published in Acta crystallographica. Section D, Biological crystallography. (01.10.2019)

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Biosynthesis of Streptolidine Involved Two Unexpected Intermediates Produced by a Dihydroxylase and a Cyclase through Unusual Mechanisms

Biosynthesis of Streptolidine Involved Two Unexpected Intermediates Produced by a Dihydroxylase and a Cyclase through Unusual Mechanisms

by Chang, Chin-Yuan, Lyu, Syue-Yi, Liu, Yu-Chen, Hsu, Ning-Shian, Wu, Chih-Chung, Tang, Cheng-Fong, Lin, Kuan-Hung, Ho, Jin-Yuan, Wu, Chang-Jer, Tsai, Ming-Daw, Li, Tsung-Lin
Published in Angewandte Chemie (10.02.2014)

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Structural and biochemical interrogation on transketolase from Pichia stipitis for new functionality

Structural and biochemical interrogation on transketolase from Pichia stipitis for new functionality

by Hsu, Li-Jen, Hsu, Ning-Shian, Wang, Yung-Lin, Wu, Chang-Jer, Li, Tsung-Lin
Published in Protein engineering, design and selection (01.11.2016)

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Multiple Complexes of Long Aliphatic N‑Acyltransferases Lead to Synthesis of 2,6-Diacylated/2-Acyl-Substituted Glycopeptide Antibiotics, Effectively Killing Vancomycin-Resistant Enterococcus

Multiple Complexes of Long Aliphatic N‑Acyltransferases Lead to Synthesis of 2,6-Diacylated/2-Acyl-Substituted Glycopeptide Antibiotics, Effectively Killing Vancomycin-Resistant Enterococcus

by Lyu, Syue-Yi, Liu, Yu-Chen, Chang, Chin-Yuan, Huang, Chuen-Jiuan, Chiu, Ya-Huang, Huang, Chun-Man, Hsu, Ning-Shian, Lin, Kuan-Hung, Wu, Chang-Jer, Tsai, Ming-Daw, Li, Tsung-Lin
Published in Journal of the American Chemical Society (06.08.2014)

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Teicoplanin Reprogrammed with the N‑Acyl-Glucosamine Pharmacophore at the Penultimate Residue of Aglycone Acquires Broad-Spectrum Antimicrobial Activities Effectively Killing Gram-Positive and -Negative Pathogens

Teicoplanin Reprogrammed with the N‑Acyl-Glucosamine Pharmacophore at the Penultimate Residue of Aglycone Acquires Broad-Spectrum Antimicrobial Activities Effectively Killing Gram-Positive and -Negative Pathogens

by Huang, Chun-Man, Lyu, Syue-Yi, Lin, Kuan-Hung, Chen, Chun-Liang, Chen, Mei-Hua, Shih, Hao-Wei, Hsu, Ning-Shian, Lo, I-Wen, Wang, Yung-Lin, Li, Yi-Shan, Wu, Chang-Jer, Li, Tsung-Lin
Published in ACS infectious diseases (08.03.2019)

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Engineering Transaldolase in Pichia stipitis to Improve Bioethanol Production

Engineering Transaldolase in Pichia stipitis to Improve Bioethanol Production

by Chen, Shan-He, Hwang, Der-Ren, Chen, Gan-Hong, Hsu, Ning-Shian, Wu, Ying-Ta, Li, Tsung-Lin, Wong, Chi-Huey
Published in ACS chemical biology (16.03.2012)

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The Mesomeric Effect of Thiazolium on non‐Kekulé Diradicals in Pichia stipitis Transketolase

The Mesomeric Effect of Thiazolium on non‐Kekulé Diradicals in Pichia stipitis Transketolase

by Hsu, Ning‐Shian, Wang, Yung‐Lin, Lin, Kuan‐Hung, Chang, Chi‐Fon, Lyu, Syue‐Yi, Hsu, Li‐Jen, Liu, Yu‐Chen, Chang, Chin‐Yuan, Wu, Chang‐Jer, Li, Tsung‐Lin
Published in Angewandte Chemie (12.02.2018)

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