Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma
Jiang, Xiaomo, Hao, Huai-Xiang, Growney, Joseph D., Woolfenden, Steve, Bottiglio, Cindy, Ng, Nicholas, Lu, Bo, Hsieh, Mindy H., Bagdasarian, Linda, Meyer, Ronald, Smith, Timothy R., Avello, Monika, Charlat, Olga, Xie, Yang, Porter, Jeffery A., Pan, Shifeng, Liu, Jun, McLaughlin, Margaret E., Cong, Feng
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
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Journal Article
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974
Liu, Jun, Pan, Shifeng, Hsieh, Mindy H., Ng, Nicholas, Sun, Fangxian, Wang, Tao, Kasibhatla, Shailaja, Schuller, Alwin G., Li, Allen G., Cheng, Dai, Li, Jie, Tompkins, Celin, Pferdekamper, AnneMarie, Steffy, Auzon, Cheng, Jane, Kowal, Colleen, Van Phung, Guo, Guirong, Wang, Yan, Graham, Martin P., Flynn, Shannon, Brenner, J. Chad, Li, Chun, Villarroel, M. Cristina, Schultz, Peter G., Xu Wu, McNamara, Peter, Sellers, William R., Petruzzelli, Lilli, Boral, Anthony L., Seidel, H. Martin, McLaughlin, Margaret E., Che, Jianwei, Carey, Thomas E., Vanasse, Gary, Harris, Jennifer L.
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2013)
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Journal Article
Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening
Zhou, Zongxiang, Patel, Manishha, Ng, Nicholas, Hsieh, Mindy H, Orth, Anthony P, Walker, John R, Batalov, Serge, Harris, Jennifer L, Liu, Jun
Published in BMC cancer (13.12.2014)
Published in BMC cancer (13.12.2014)
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Journal Article
Regenerative phenotype in mice with a point mutation in transforming growth factor β type I receptor (TGFBR1)
Liu, Jun, Johnson, Kristen, Li, Jie, Piamonte, Victoria, Steffy, Brian M., Hsieh, Mindy H., Ng, Nicholas, Zhang, Jay, Walker, John R., Ding, Sheng, Muneoka, Ken, Wu, Xu, Glynne, Richard, Schultz, Peter G.
Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2011)
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Journal Article
Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling
Chen, Chih-Wei, Beyer, Christian, Liu, Jun, Maier, Christiane, Li, Chun, Trinh-Minh, Thuong, Xu, Xiaohan, Cole, Stuart H, Hsieh, Mindy H, Ng, Nicholas, Althage, Alana, Meeusen, Shelly, Pan, Shifeng, Svensson, Eric C, Seidel, H Martin, Schett, Georg, Gergely, Peter, Harris, Jennifer L, Distler, Jörg H W
Published in Annals of the rheumatic diseases (01.04.2017)
Published in Annals of the rheumatic diseases (01.04.2017)
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Journal Article
Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors
Cheng, Dai, Liu, Jun, Han, Dong, Zhang, Guobao, Gao, Wenqi, Hsieh, Mindy H, Ng, Nicholas, Kasibhatla, Shailaja, Tompkins, Celin, Li, Jie, Steffy, Auzon, Sun, Fangxian, Li, Chun, Seidel, H. Martin, Harris, Jennifer L, Pan, Shifeng
Published in ACS medicinal chemistry letters (14.07.2016)
Published in ACS medicinal chemistry letters (14.07.2016)
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Journal Article
Regenerative phenotype in mice with a point mutation in transforming growth factor [Beta] type I receptor (TGFBR1)
Liu, Jun, Johnson, Kristen, Li, Jie, Piamonte, Victoria, Steffy, Brian M, Hsieh, Mindy H, Ng, Nicholas, Zhang, Jay, Walker, John R, Ding, Sheng, Muneoka, Ken, Wu, Xu, Glynne, Richard, Schultz, Peter G
Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2011)
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Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2011)
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