Biphasic MLL takes helm at cell cycle control: Implications in human mixed lineage leukemia
Liu, Han, Takeda, Shugaku, Cheng, Emily H.Y., Hsieh, James J.D.
Published in Cell cycle (Georgetown, Tex.) (15.02.2008)
Published in Cell cycle (Georgetown, Tex.) (15.02.2008)
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Journal Article
Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer
Vanharanta, Sakari, Shu, Weiping, Brenet, Fabienne, Hakimi, A Ari, Heguy, Adriana, Viale, Agnes, Reuter, Victor E, Hsieh, James J-D, Scandura, Joseph M, Massagué, Joan
Published in Nature medicine (01.01.2013)
Published in Nature medicine (01.01.2013)
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Journal Article
BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program
Ren, Decheng, Tu, Ho-Chou, Kim, Hyungjin, Wang, Gary X, Bean, Gregory R, Takeuchi, Osamu, Jeffers, John R, Zambetti, Gerard P, Hsieh, James J.-D, Cheng, Emily H.-Y
Published in Science (American Association for the Advancement of Science) (03.12.2010)
Published in Science (American Association for the Advancement of Science) (03.12.2010)
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Journal Article
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint
Hsieh, James J.-D, Liu, Han, Takeda, Shugaku, Kumar, Rakesh, Westergard, Todd D, Brown, Eric J, Pandita, Tej K, Cheng, Emily H.-Y
Published in Nature (London) (16.09.2010)
Published in Nature (London) (16.09.2010)
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Journal Article
PUMA and BIM are required for oncogene inactivation-induced apoptosis
Bean, Gregory R, Ganesan, Yogesh Tengarai, Dong, Yiyu, Takeda, Shugaku, Liu, Han, Chan, Po M, Huang, Yafen, Chodosh, Lewis A, Zambetti, Gerard P, Hsieh, James J-D, Cheng, Emily H-Y
Published in Science signaling (26.03.2013)
Published in Science signaling (26.03.2013)
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Journal Article
The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations
Huang, Gang, Zhao, Xinghui, Wang, Lan, Elf, Shannon, Xu, Hao, Zhao, Xinyang, Sashida, Goro, Zhang, Yue, Liu, Yan, Lee, Jennifer, Menendez, Silvia, Yang, Youyang, Yan, Xiaomei, Zhang, Pu, Tenen, Daniel G., Osato, Motomi, Hsieh, James J.-D., Nimer, Stephen D.
Published in Blood (15.12.2011)
Published in Blood (15.12.2011)
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Journal Article
p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage
Tu, Ho-Chou, Ren, Decheng, Wang, Gary X, Chen, David Y, Westergard, Todd D, Kim, Hyungjin, Sasagawa, Satoru, Hsieh, James J.-D, Cheng, Emily H.-Y
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2009)
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Journal Article
Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression
Takeda, Shugaku, Chen, David Y, Westergard, Todd D, Fisher, Jill K, Rubens, Jeffrey A, Sasagawa, Satoru, Kan, Jason T, Korsmeyer, Stanley J, Cheng, Emily H-Y, Hsieh, James J-D
Published in Genes & development (01.09.2006)
Published in Genes & development (01.09.2006)
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Journal Article
Species Selectivity of Mixed-Lineage Leukemia/Trithorax and HCF Proteolytic Maturation Pathways
Capotosti, Francesca, Hsieh, James J.-D., Herr, Winship
Published in Molecular and Cellular Biology (01.10.2007)
Published in Molecular and Cellular Biology (01.10.2007)
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Journal Article
Proteolytic Cleavage of MLL Generates a Complex of N- and C-Terminal Fragments That Confers Protein Stability and Subnuclear Localization
Hsieh, James J.-D., Ernst, Patricia, Erdjument-Bromage, Hediye, Tempst, Paul, Korsmeyer, Stanley J.
Published in Molecular and Cellular Biology (01.01.2003)
Published in Molecular and Cellular Biology (01.01.2003)
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Journal Article
A Pharmacologic Inhibitor of the Protease Taspase1 Effectively Inhibits Breast and Brain Tumor Growth
CHEN, David Y, LEE, Yishan, OH, Kyoung J, KORSMEYER, Stanley J, HERMONE, Ann, GUSSIO, Richard, SHOEMAKER, Robert H, CHENG, Emily H.-Y, HSIEH, James J.-D, VAN TINE, Brian A, SEARLEMAN, Adam C, WESTERGARD, Todd D, HAN LIU, TU, Ho-Chou, TAKEDA, Shugaku, YIYU DONG, PIWNICA-WORMS, David R
Published in Cancer research (Chicago, Ill.) (01.02.2012)
Published in Cancer research (Chicago, Ill.) (01.02.2012)
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Journal Article
Taspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosis
Chen, David Y, Liu, Han, Takeda, Shugaku, Tu, Ho-Chou, Sasagawa, Satoru, Van Tine, Brian A, Lu, Dongsi, Cheng, Emily H-Y, Hsieh, James J-D
Published in Cancer research (Chicago, Ill.) (01.07.2010)
Published in Cancer research (Chicago, Ill.) (01.07.2010)
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Journal Article
The VDAC2-BAK rheostat controls thymocyte survival
Ren, Decheng, Kim, Hyungjin, Tu, Ho-Chou, Westergard, Todd D, Fisher, Jill K, Rubens, Jeff A, Korsmeyer, Stanley J, Hsieh, James J-D, Cheng, Emily H-Y
Published in Science signaling (25.08.2009)
Published in Science signaling (25.08.2009)
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Journal Article
SKIP, a CBF1-Associated Protein, Interacts with the Ankyrin Repeat Domain of NotchIC To Facilitate NotchIC Function
Zhou, Sifang, Fujimuro, Masahiro, Hsieh, James J.-D., Chen, Lin, Miyamoto, Alison, Weinmaster, Gerry, Hayward, S. Diane
Published in Molecular and Cellular Biology (01.04.2000)
Published in Molecular and Cellular Biology (01.04.2000)
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Journal Article
Design, syntheses, and evaluation of Taspase1 inhibitors
Lee, Jeong Tae, Chen, David Y., Yang, Zhimou, Ramos, Alexander D., Hsieh, James J.-D., Bogyo, Matthew
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
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