The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination
Zhao, Weixing, Wiese, Claudia, Kwon, Youngho, Hromas, Robert, Sung, Patrick
Published in Annual review of biochemistry (20.06.2019)
Published in Annual review of biochemistry (20.06.2019)
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Structural basis of RNA cap modification by SARS-CoV-2
Viswanathan, Thiruselvam, Arya, Shailee, Chan, Siu-Hong, Qi, Shan, Dai, Nan, Misra, Anurag, Park, Jun-Gyu, Oladunni, Fatai, Kovalskyy, Dmytro, Hromas, Robert A., Martinez-Sobrido, Luis, Gupta, Yogesh K.
Published in Nature communications (24.07.2020)
Published in Nature communications (24.07.2020)
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Drugging the Cancers Addicted to DNA Repair
Nickoloff, Jac A, Jones, Dennie, Lee, Suk-Hee, Williamson, Elizabeth A, Hromas, Robert
Published in JNCI : Journal of the National Cancer Institute (01.11.2017)
Published in JNCI : Journal of the National Cancer Institute (01.11.2017)
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EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair
Wu, Yuehan, Lee, Suk-Hee, Williamson, Elizabeth A, Reinert, Brian L, Cho, Ju Hwan, Xia, Fen, Jaiswal, Aruna Shanker, Srinivasan, Gayathri, Patel, Bhavita, Brantley, Alexis, Zhou, Daohong, Shao, Lijian, Pathak, Rupak, Hauer-Jensen, Martin, Singh, Sudha, Kong, Kimi, Wu, Xaiohua, Kim, Hyun-Suk, Beissbarth, Timothy, Gaedcke, Jochen, Burma, Sandeep, Nickoloff, Jac A, Hromas, Robert A
Published in PLoS genetics (01.12.2015)
Published in PLoS genetics (01.12.2015)
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Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence
Fletcher-Sananikone, Eliot, Kanji, Suman, Tomimatsu, Nozomi, Di Cristofaro, Luis Fernando Macedo, Kollipara, Rahul K, Saha, Debabrata, Floyd, John R, Sung, Patrick, Hromas, Robert, Burns, Terry C, Kittler, Ralf, Habib, Amyn A, Mukherjee, Bipasha, Burma, Sandeep
Published in Cancer research (Chicago, Ill.) (01.12.2021)
Published in Cancer research (Chicago, Ill.) (01.12.2021)
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Synthetic lethality: exploiting the addiction of cancer to DNA repair
Shaheen, Montaser, Allen, Christopher, Nickoloff, Jac A., Hromas, Robert
Published in Blood (09.06.2011)
Published in Blood (09.06.2011)
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Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity
Lv, Dongwen, Pal, Pratik, Liu, Xingui, Jia, Yannan, Thummuri, Dinesh, Zhang, Peiyi, Hu, Wanyi, Pei, Jing, Zhang, Qi, Zhou, Shuo, Khan, Sajid, Zhang, Xuan, Hua, Nan, Yang, Qingping, Arango, Sebastian, Zhang, Weizhou, Nayak, Digant, Olsen, Shaun K., Weintraub, Susan T., Hromas, Robert, Konopleva, Marina, Yuan, Yaxia, Zheng, Guangrong, Zhou, Daohong
Published in Nature communications (25.11.2021)
Published in Nature communications (25.11.2021)
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Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Yonghan, Khan, Sajid, Huo, Zhiguang, Lv, Dongwen, Zhang, Xuan, Liu, Xingui, Yuan, Yaxia, Hromas, Robert, Xu, Mingjiang, Zheng, Guangrong, Zhou, Daohong
Published in Journal of hematology and oncology (27.07.2020)
Published in Journal of hematology and oncology (27.07.2020)
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DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response
Liang, Fengshan, Miller, Adam S., Longerich, Simonne, Tang, Caroline, Maranon, David, Williamson, Elizabeth A., Hromas, Robert, Wiese, Claudia, Kupfer, Gary M., Sung, Patrick
Published in Nature communications (28.06.2019)
Published in Nature communications (28.06.2019)
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Roles of homologous recombination in response to ionizing radiation-induced DNA damage
Nickoloff, Jac A., Sharma, Neelam, Allen, Christopher P., Taylor, Lynn, Allen, Sage J., Jaiswal, Aruna S., Hromas, Robert
Published in International journal of radiation biology (03.06.2023)
Published in International journal of radiation biology (03.06.2023)
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Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining
Fnu, Sheema, Williamson, Elizabeth A., De Haro, Leyma P., Brenneman, Mark, Wray, Justin, Shaheen, Montaser, Radhakrishnan, Krishnan, Lee, Suk-Hee, Nickoloff, Jac A., Hromas, Robert, Kolodner, Richard D.
Published in Proceedings of the National Academy of Sciences - PNAS (11.01.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (11.01.2011)
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Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL
Nayak, Digant, Lv, Dongwen, Yuan, Yaxia, Zhang, Peiyi, Hu, Wanyi, Nayak, Anindita, Ruben, Eliza A., Lv, Zongyang, Sung, Patrick, Hromas, Robert, Zheng, Guangrong, Zhou, Daohong, Olsen, Shaun K.
Published in Nature communications (29.03.2024)
Published in Nature communications (29.03.2024)
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Targeting pheochromocytoma/paraganglioma with polyamine inhibitors
Rai, Sudhir Kumar, Bril, Fernando, Hatch, Heather M., Xu, Yiling, Shelton, Laura, Kalavalapalli, Srilaxmi, Click, Arielle, Lee, Douglas, Beecher, Chris, Kirby, Austin, Kong, Kimi, Trevino, Jose, Jha, Abhishek, Jatav, Shashank, Kriti, Kriti, Luthra, Soumya, Garrett, Timothy J., Guingab-Cagmat, Joy, Plant, Daniel, Bose, Prodip, Cusi, Kenneth, Hromas, Robert A., Tischler, Arthur S., Powers, James F., Gupta, Priyanka, Bibb, James, Beuschlein, Felix, Robledo, Mercedes, Calsina, Bruna, Timmers, Henri, Taieb, David, Kroiss, Matthias, Richter, Susan, Langton, Katharina, Eisenhofer, Graeme, Bergeron, Raymond, Pacak, Karel, Tevosian, Sergei G., Ghayee, Hans K.
Published in Metabolism, clinical and experimental (01.09.2020)
Published in Metabolism, clinical and experimental (01.09.2020)
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Cellular Responses to Widespread DNA Replication Stress
Nickoloff, Jac A, Jaiswal, Aruna S, Sharma, Neelam, Williamson, Elizabeth A, Tran, Manh T, Arris, Dominic, Yang, Ming, Hromas, Robert
Published in International journal of molecular sciences (01.12.2023)
Published in International journal of molecular sciences (01.12.2023)
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Journal Article
DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation
Kwon, Youngho, Rösner, Heike, Zhao, Weixing, Selemenakis, Platon, He, Zhuoling, Kawale, Ajinkya S., Katz, Jeffrey N., Rogers, Cody M., Neal, Francisco E., Badamchi Shabestari, Aida, Petrosius, Valdemaras, Singh, Akhilesh K., Joel, Marina Z., Lu, Lucy, Holloway, Stephen P., Burma, Sandeep, Mukherjee, Bipasha, Hromas, Robert, Mazin, Alexander, Wiese, Claudia, Sørensen, Claus S., Sung, Patrick
Published in Nature communications (26.01.2023)
Published in Nature communications (26.01.2023)
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RNA binding to human METTL3-METTL14 restricts N 6 -deoxyadenosine methylation of DNA in vitro
Qi, Shan, Mota, Javier, Chan, Siu-Hong, Villarreal, Johanna, Dai, Nan, Arya, Shailee, Hromas, Robert A, Rao, Manjeet K, Corrêa, Jr, Ivan R, Gupta, Yogesh K
Published in eLife (21.01.2022)
Published in eLife (21.01.2022)
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Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
Sullivan, Katherine, Cramer-Morales, Kimberly, McElroy, Daniel L, Ostrov, David A, Haas, Kimberly, Childers, Wayne, Hromas, Robert, Skorski, Tomasz
Published in PloS one (19.01.2016)
Published in PloS one (19.01.2016)
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Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions
Daley, James M., Tomimatsu, Nozomi, Hooks, Grace, Wang, Weibin, Miller, Adam S., Xue, Xiaoyu, Nguyen, Kevin A., Kaur, Hardeep, Williamson, Elizabeth, Mukherjee, Bipasha, Hromas, Robert, Burma, Sandeep, Sung, Patrick
Published in Nature communications (18.06.2020)
Published in Nature communications (18.06.2020)
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