High-throughput salting-out assisted liquid-liquid extraction using a 3D printed device and its application in the quantification of ibrutinib and its metabolite PCI-45227 in human serum
Écsiová, Dominika, Šimkovič, Martin, Uher, Martin, Hroch, Miloš
Published in Journal of pharmaceutical and biomedical analysis (20.09.2022)
Published in Journal of pharmaceutical and biomedical analysis (20.09.2022)
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Synthesis of [13C6]‐ibrutinib
Kriegelstein, Michal, Hroch, Miloš, Marek, Aleš
Published in Journal of labelled compounds & radiopharmaceuticals (01.11.2021)
Published in Journal of labelled compounds & radiopharmaceuticals (01.11.2021)
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Direct Multi‐Deuterium Labelling of Pirtobrutinib
Kriegelstein, Michal, Hojcsková, Jana, Hroch, Miloš, Marek, Aleš
Published in Journal of labelled compounds & radiopharmaceuticals (01.07.2024)
Published in Journal of labelled compounds & radiopharmaceuticals (01.07.2024)
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Semisynthetic derivatives of haemanthamine and their in vitro antiproliferative activity evaluation against a panel of human cell lines
Uher, Martin, Hroch, Miloš, Peřinová, Rozálie, Havelek, Radim, Křoustková, Jana, Řezáčová, Martina, Muthná, Darina, Koutová, Darja, Kuneš, Jiří, Cahlíková, Lucie
Published in Arabian journal of chemistry (01.05.2022)
Published in Arabian journal of chemistry (01.05.2022)
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Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis
Lastuvkova, Hana, Faradonbeh, Fatemeh Alaei, Schreiberova, Jolana, Hroch, Milos, Mokry, Jaroslav, Faistova, Hana, Nova, Zuzana, Hyspler, Radomír, Igreja Sa, Ivone Cristina, Nachtigal, Petr, Stefela, Alzbeta, Pavek, Petr, Micuda, Stanislav
Published in International journal of molecular sciences (16.06.2021)
Published in International journal of molecular sciences (16.06.2021)
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In vitro and in vivo metabolism of 3-quinuclidinyl benzilate by high-resolution mass spectrometry
Uher, Martin, Mžik, Martin, Karasová, Jana Žďárová, Herman, David, Čechová, Lenka, Dlabková, Alžběta, Mrkvicová, Alena, Hroch, Miloš
Published in Journal of pharmaceutical and biomedical analysis (25.10.2020)
Published in Journal of pharmaceutical and biomedical analysis (25.10.2020)
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Multidrug Resistance-Associated Protein 2 Deficiency Aggravates Estrogen-Induced Impairment of Bile Acid Metabolomics in Rats
Alaei Faradonbeh, Fatemeh, Lastuvkova, Hana, Cermanova, Jolana, Hroch, Milos, Nova, Zuzana, Uher, Martin, Hirsova, Petra, Pavek, Petr, Micuda, Stanislav
Published in Frontiers in physiology (21.03.2022)
Published in Frontiers in physiology (21.03.2022)
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Labetalol and soluble endoglin aggravate bile acid retention in mice with ethinylestradiol-induced cholestasis
Cristina Igreja Sá, Ivone, Tripska, Katarina, Alaei Faradonbeh, Fatemeh, Hroch, Milos, Lastuvkova, Hana, Schreiberova, Jolana, Kacerovsky, Marian, Pericacho, Miguel, Nachtigal, Petr, Micuda, Stanislav
Published in Frontiers in pharmacology (26.01.2023)
Published in Frontiers in pharmacology (26.01.2023)
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Soluble Endoglin as a Potential Biomarker of Nonalcoholic Steatohepatitis (NASH) Development, Participating in Aggravation of NASH-Related Changes in Mouse Liver
Igreja Sá, Ivone Cristina, Tripska, Katarina, Hroch, Milos, Hyspler, Radomir, Ticha, Alena, Lastuvkova, Hana, Schreiberova, Jolana, Dolezelova, Eva, Eissazadeh, Samira, Vitverova, Barbora, Najmanova, Iveta, Vasinova, Martina, Pericacho, Miguel, Micuda, Stanislav, Nachtigal, Petr
Published in International journal of molecular sciences (27.11.2020)
Published in International journal of molecular sciences (27.11.2020)
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Development of an HPLC fluorescence method for determination of boldine in plasma, bile and urine of rats and identification of its major metabolites by LC–MS/MS
Hroch, Miloš, Mičuda, Stanislav, Cermanová, Jolana, Chládek, Jaroslav, Tomšík, Pavel
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.10.2013)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.10.2013)
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Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats
Dolezelova, Eva, Prasnicka, Alena, Cermanova, Jolana, Carazo, Alejandro, Hyrsova, Lucie, Hroch, Milos, Mokry, Jaroslav, Adamcova, Michaela, Mrkvicova, Alena, Pavek, Petr, Micuda, Stanislav
Published in World journal of gastroenterology : WJG (21.11.2017)
Published in World journal of gastroenterology : WJG (21.11.2017)
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Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane
Lenčová-Popelová, Olga, Jirkovský, Eduard, Jansová, Hana, Jirkovská-Vávrová, Anna, Vostatková-Tichotová, Lucie, Mazurová, Yvona, Adamcová, Michaela, Chládek, Jaroslav, Hroch, Miloš, Pokorná, Zuzana, Geršl, Vladimír, Šimůnek, Tomáš, Štěrba, Martin
Published in Journal of molecular and cellular cardiology (01.02.2016)
Published in Journal of molecular and cellular cardiology (01.02.2016)
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Boldine Inhibits Mouse Mammary Carcinoma In Vivo and Human MCF-7 Breast Cancer Cells In Vitro
Tomšík, Pavel, Mičuda, Stanislav, Muthná, Darina, Čermáková, Eva, Havelek, Radim, Rudolf, Emil, Hroch, Miloš, Kadová, Zuzana, Řezáčová, Martina, Ćmielová, Jana, Živný, Pavel
Published in Planta medica (01.11.2016)
Published in Planta medica (01.11.2016)
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Chronic anthracycline cardiotoxicity: molecular and functional analysis with focus on nuclear factor erythroid 2-related factor 2 and mitochondrial biogenesis pathways
Jirkovsky, Eduard, Popelová, Olga, Kriváková-Stanková, Pavla, Vávrová, Anna, Hroch, Milos, Hasková, Pavlína, Brcáková-Dolezelová, Eva, Micuda, Stanislav, Adamcová, Michaela, Simůnek, Tomás, Cervinková, Zuzana, Gersl, Vladimír, Sterba, Martin
Published in The Journal of pharmacology and experimental therapeutics (01.11.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2012)
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Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits
Jirkovský, Eduard, Lenčová-Popelová, Olga, Hroch, Miloš, Adamcová, Michaela, Mazurová, Yvona, Vávrová, Jaroslava, Mičuda, Stanislav, Šimůnek, Tomáš, Geršl, Vladimír, Štěrba, Martin
Published in Toxicology (Amsterdam) (15.09.2013)
Published in Toxicology (Amsterdam) (15.09.2013)
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[(p-MeC6H4Pr )2Ru2(SC6H4-p-Bu )3]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study
Tomšík, Pavel, Muthná, Darina, Řezáčová, Martina, Mičuda, Stanislav, Ćmielová, Jana, Hroch, Miloš, Endlicher, René, Červinková, Zuzana, Rudolf, Emil, Hann, Stephan, Stíbal, David, Therrien, Bruno, Süss-Fink, Georg
Published in Journal of organometallic chemistry (15.04.2015)
Published in Journal of organometallic chemistry (15.04.2015)
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HPLC determination of arginases inhibitor N-(ω)-hydroxy-nor-l-arginine using core–shell particle column and LC–MS/MS identification of principal metabolite in rat plasma
Hroch, Miloš, Havlínová, Zuzana, Nobilis, Milan, Chládek, Jaroslav
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.01.2012)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.01.2012)
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