P53: A Guardian of Immunity Becomes Its Saboteur through Mutation
Agupitan, Arjelle Decasa, Neeson, Paul, Williams, Scott, Howitt, Jason, Haupt, Sue, Haupt, Ygal
Published in International journal of molecular sciences (13.05.2020)
Published in International journal of molecular sciences (13.05.2020)
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Journal Article
The tumor suppressor PTEN is exported in exosomes and has phosphatase activity in recipient cells
Putz, Ulrich, Howitt, Jason, Doan, Anh, Goh, Choo-Peng, Low, Ley-Hian, Silke, John, Tan, Seong-Seng
Published in Science signaling (25.09.2012)
Published in Science signaling (25.09.2012)
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Journal Article
Oligomerization‐driven MLKL ubiquitylation antagonizes necroptosis
Liu, Zikou, Dagley, Laura F, Shield‐Artin, Kristy, Young, Samuel N, Bankovacki, Aleksandra, Wang, Xiangyi, Tang, Michelle, Howitt, Jason, Stafford, Che A, Nachbur, Ueli, Fitzgibbon, Cheree, Garnish, Sarah E, Webb, Andrew I, Komander, David, Murphy, James M, Hildebrand, Joanne M, Silke, John
Published in The EMBO journal (01.12.2021)
Published in The EMBO journal (01.12.2021)
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Journal Article
Nedd4 Family-interacting Protein 1 (Ndfip1) Is Required for the Exosomal Secretion of Nedd4 Family Proteins
Putz, Ulrich, Howitt, Jason, Lackovic, Jenny, Foot, Natalie, Kumar, Sharad, Silke, John, Tan, Seong-Seng
Published in The Journal of biological chemistry (21.11.2008)
Published in The Journal of biological chemistry (21.11.2008)
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Journal Article
Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia
Howitt, Jason, Lackovic, Jenny, Low, Ley-Hian, Naguib, Adam, Macintyre, Alison, Goh, Choo-Peng, Callaway, Jennifer K, Hammond, Vicki, Thomas, Tim, Dixon, Matthew, Putz, Ulrich, Silke, John, Bartlett, Perry, Yang, Baoli, Kumar, Sharad, Trotman, Lloyd C, Tan, Seong-Seng
Published in The Journal of cell biology (09.01.2012)
Published in The Journal of cell biology (09.01.2012)
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Journal Article
Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons
Howitt, Jason, Putz, Ulrich, Lackovic, Jenny, Doan, Anh, Dorstyn, Loretta, Cheng, Hong, Yang, Baoli, Chan-Ling, Tailoi, Silke, John, Kumar, Sharad, Tan, Seong-Seng
Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2009)
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Journal Article
Increased Ndfip1 in the substantia nigra of Parkinsonian brains is associated with elevated iron levels
Howitt, Jason, Gysbers, Amanda M, Ayton, Scott, Carew-Jones, Francine, Putz, Ulrich, Finkelstein, David I, Halliday, Glenda M, Tan, Seong-Seng
Published in PloS one (24.01.2014)
Published in PloS one (24.01.2014)
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Journal Article
The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8+ T Cell Tolerance Checkpoint to High-Dose Antigen
Wagle, Mayura V., Marchingo, Julia M., Howitt, Jason, Tan, Seong-Seng, Goodnow, Christopher C., Parish, Ian A.
Published in Cell reports (Cambridge) (17.07.2018)
Published in Cell reports (Cambridge) (17.07.2018)
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Journal Article
A Molecular Mechanism for the Heparan Sulfate Dependence of Slit-Robo Signaling
Hussain, Sadaf-Ahmahni, Piper, Michael, Fukuhara, Noémi, Strochlic, Laure, Cho, Gian, Howitt, Jason A., Ahmed, Yassir, Powell, Andrew K., Turnbull, Jeremy E., Holt, Christine E., Hohenester, Erhard
Published in The Journal of biological chemistry (22.12.2006)
Published in The Journal of biological chemistry (22.12.2006)
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Journal Article
Rab5 and Ndfip1 Are Involved in Pten Ubiquitination and Nuclear Trafficking
Li, Yijia, Low, Ley‐Hian, Putz, Ulrich, Goh, Choo‐Peng, Tan, Seong‐Seng, Howitt, Jason
Published in Traffic (Copenhagen, Denmark) (01.07.2014)
Published in Traffic (Copenhagen, Denmark) (01.07.2014)
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Journal Article
Ndfip1 is required for the development of pyramidal neuron dendrites and spines in the neocortex
Hammond, Vicki E, Gunnersen, Jenny M, Goh, Choo-Peng, Low, Ley-Hian, Hyakumura, Tomoko, Tang, Michelle M, Britto, Joanne M, Putz, Ulrich, Howitt, Jason A, Tan, Seong-Seng
Published in Cerebral cortex (New York, N.Y. 1991) (01.12.2014)
Published in Cerebral cortex (New York, N.Y. 1991) (01.12.2014)
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Journal Article
BDNF Exerts Contrasting Effects on Peripheral Myelination of NGF-Dependent and BDNF-Dependent DRG Neurons
Xiao, Junhua, Wong, Agnes W, Willingham, Melanie M, Kaasinen, Selma K, Hendry, Ian A, Howitt, Jason, Putz, Ulrich, Barrett, Graham L, Kilpatrick, Trevor J, Murray, Simon S
Published in The Journal of neuroscience (01.04.2009)
Published in The Journal of neuroscience (01.04.2009)
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Journal Article
Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4⁺ T cells
Altin, John A., Daley, Stephen R., Howitt, Jason, Rickards, Helen J., Batkin, Alison K., Horikawa, Keisuke, Prasad, Simon J., Nelms, Keats A., Kumar, Sharad, Wu, Lawren C., Tan, Seong-Seng, Cook, Matthew C., Goodnow, Christopher C.
Published in Proceedings of the National Academy of Sciences - PNAS (11.02.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (11.02.2014)
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Journal Article
Engineered Exosomes as Vehicles for Biologically Active Proteins
Sterzenbach, Ulrich, Putz, Ulrich, Low, Ley-Hian, Silke, John, Tan, Seong-Seng, Howitt, Jason
Published in Molecular therapy (07.06.2017)
Published in Molecular therapy (07.06.2017)
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