A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis
Magliozzi, Roberta, Howell, Owain W., Reeves, Cheryl, Roncaroli, Federico, Nicholas, Richard, Serafini, Barbara, Aloisi, Francesca, Reynolds, Richard
Published in Annals of neurology (01.10.2010)
Published in Annals of neurology (01.10.2010)
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Journal Article
Inflammatory intrathecal profiles and cortical damage in multiple sclerosis
Magliozzi, Roberta, Howell, Owain W., Nicholas, Richard, Cruciani, Carolina, Castellaro, Marco, Romualdi, Chiara, Rossi, Stefania, Pitteri, Marco, Benedetti, Maria Donata, Gajofatto, Alberto, Pizzini, Francesca B., Montemezzi, Stefania, Rasia, Sarah, Capra, Ruggero, Bertoldo, Alessandra, Facchiano, Francesco, Monaco, Salvatore, Reynolds, Richard, Calabrese, Massimiliano
Published in Annals of neurology (01.04.2018)
Published in Annals of neurology (01.04.2018)
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Journal Article
Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism
Yutuc, Eylan, Angelini, Roberto, Baumert, Mark, Mast, Natalia, Pikuleva, Irina, Newton, Jillian, Clench, Malcolm R., Skibinski, David O. F., Howell, Owain W., Wang, Yuqin, Griffiths, William J.
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2020)
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Journal Article
Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier
Gallego-Delgado, Patricia, James, Rachel, Browne, Eleanor, Meng, Joanna, Umashankar, Swetha, Tan, Li, Picon, Carmen, Mazarakis, Nicholas D, Faisal, A Aldo, Howell, Owain W, Reynolds, Richard
Published in PLoS biology (01.12.2020)
Published in PLoS biology (01.12.2020)
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Journal Article
Complement activation and increased anaphylatoxin receptor expression are associated with cortical grey matter lesions and the compartmentalised inflammatory response of multiple sclerosis
Evans, Rhian, Watkins, Lewis M, Hawkins, Kristen, Santiago, Gabriella, Demetriou, Constantinos, Naughton, Michelle, Dittmer, Marie, Rees, Mark I, Fitzgerald, Denise, Morgan, B Paul, Neal, James W, Howell, Owain W
Published in Frontiers in cellular neuroscience (22.03.2023)
Published in Frontiers in cellular neuroscience (22.03.2023)
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Journal Article
Two binding sites for [ H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation
Owen, David R, Howell, Owain W, Tang, Sac-Pham, Wells, Lisa A, Bennacef, Idriss, Bergstrom, Mats, Gunn, Roger N, Rabiner, Eugenii A, Wilkins, Martin R, Reynolds, Richard, Matthews, Paul M, Parker, Christine A
Published in Journal of cerebral blood flow and metabolism (01.09.2010)
Published in Journal of cerebral blood flow and metabolism (01.09.2010)
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Journal Article
Metabolic profiling in serum, cerebrospinal fluid, and brain of patients with cerebrotendinous xanthomatosis
Höflinger, Philip, Hauser, Stefan, Yutuc, Eylan, Hengel, Holger, Griffiths, Lauren, Radelfahr, Florentine, Howell, Owain W., Wang, Yuqin, Connor, Sonja L., Duell, P. Barton, DeBarber, Andrea E., Martus, Peter, Lütjohann, Dieter, Griffiths, William J., Schöls, Ludger
Published in Journal of lipid research (01.01.2021)
Published in Journal of lipid research (01.01.2021)
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Journal Article
Complement activation in multiple sclerosis plaques: an immunohistochemical analysis
Ingram, Gillian, Loveless, Sam, Howell, Owain W, Hakobyan, Svetlana, Dancey, Bethan, Harris, Claire L, Robertson, Neil P, Neal, James W, Morgan, B Paul
Published in Acta neuropathologica communications (09.05.2014)
Published in Acta neuropathologica communications (09.05.2014)
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Journal Article
Analysis of target mRNAs in the fixed-frozen human brain using a modified BaseScope-ISH Assay protocol
Carisì, M. Carla, Howell, Owain W., Morgan, Alwena H., Davies, Jeffrey S.
Published in STAR protocols (16.12.2022)
Published in STAR protocols (16.12.2022)
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Journal Article
B cell rich meningeal inflammation associates with increased spinal cord pathology in multiple sclerosis
Reali, Camilla, Magliozzi, Roberta, Roncaroli, Federico, Nicholas, Richard, Howell, Owain W., Reynolds, Richard
Published in Brain pathology (Zurich, Switzerland) (01.07.2020)
Published in Brain pathology (Zurich, Switzerland) (01.07.2020)
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Journal Article
Neuropeptide Y stimulates neuronal precursor proliferation in the post‐natal and adult dentate gyrus
Howell, Owain W., Doyle, Kharen, Goodman, Jeffrey H., Scharfman, Helen E., Herzog, Herbert, Pringle, Ashley, Beck‐Sickinger, Annette G., Gray, William P.
Published in Journal of neurochemistry (01.05.2005)
Published in Journal of neurochemistry (01.05.2005)
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Journal Article
Neuropeptide Y is important for basal and seizure-induced precursor cell proliferation in the hippocampus
Howell, Owain W, Silva, Sharmalene, Scharfman, Helen E, Sosunov, Alexander A, Zaben, Malik, Shatya, Anan, Mckhann, Guy, Herzog, Herbert, Laskowski, Alexandra, Gray, William P
Published in Neurobiology of disease (01.04.2007)
Published in Neurobiology of disease (01.04.2007)
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Journal Article
Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development
Hennegan, James, Bryant, Aled H., Griffiths, Lauren, Trigano, Matthieu, Bartley, Oliver J.M., Bartlett, Joanna J., Minahan, Carys, Abreu de Oliveira, Willy Antoni, Yutuc, Eylan, Ntikas, Sotirios, Bartsocas, Christos S., Markouri, Margarita, Antoniadou, Eleni, Laina, Ioanna, Howell, Owain W., Li, Meng, Wang, Yuqin, Griffiths, William J., Lane, Emma L., Lelos, Mariah J., Theofilopoulos, Spyridon
Published in iScience (19.01.2024)
Published in iScience (19.01.2024)
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Journal Article
Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis
Howell, Owain W., Reeves, Cheryl A., Nicholas, Richard, Carassiti, Daniele, Radotra, Bishan, Gentleman, Steve M., Serafini, Barbara, Aloisi, Francesca, Roncaroli, Federico, Magliozzi, Roberta, Reynolds, Richard
Published in Brain (London, England : 1878) (01.09.2011)
Published in Brain (London, England : 1878) (01.09.2011)
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Journal Article
Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats
GARDNER, Christopher, MAGLIOZZI, Roberta, DURRENBERGER, Pascal F, HOWELL, Owain W, RUNDLE, Jon, REYNOLDS, Richard
Published in Brain (London, England : 1878) (01.12.2013)
Published in Brain (London, England : 1878) (01.12.2013)
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Journal Article
Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis
CHOI, Sung R, HOWELL, Owain W, CARASSITI, Daniele, MAGLIOZZI, Roberta, GVERIC, Djordje, MURARO, Paolo A, NICHOLAS, Richard, RONCAROLI, Federico, REYNOLDS, Richard
Published in Brain (London, England : 1878) (01.10.2012)
Published in Brain (London, England : 1878) (01.10.2012)
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Journal Article
Meningeal inflammation and cortical demyelination in acute multiple sclerosis
Bevan, Ryan J., Evans, Rhian, Griffiths, Lauren, Watkins, Lewis M., Rees, Mark I., Magliozzi, Roberta, Allen, Ingrid, McDonnell, Gavin, Kee, Rachel, Naughton, Michelle, Fitzgerald, Denise C., Reynolds, Richard, Neal, James W., Howell, Owain W.
Published in Annals of neurology (01.12.2018)
Published in Annals of neurology (01.12.2018)
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